Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population

High-mobility group AT-hook 1 (HMGA1) is an important regulator of the insulin receptor gene. We have previously shown in three populations of white European ancestry that the HMGA1 gene variant rs146052672 (also designated IVS5-13insC) is associated with type 2 diabetes mellitus (T2DM). The aim of...

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Veröffentlicht in:	Metabolic syndrome and related disorders 2014-02, Vol.12 (1), p.25-30
Hauptverfasser:	Pullinger, Clive R, Goldfine, Ira D, Tanyolaç, Sinan, Movsesyan, Irina, Faynboym, Mark, Durlach, Vincent, Chiefari, Eusebio, Foti, Daniela P, Frost, Philip H, Malloy, Mary J, Brunetti, Antonio, Kane, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiposity - genetics Aged Anthropometry Body Mass Index Cholesterol, HDL - blood Diabetes Mellitus, Type 2 - ethnology Diabetes Mellitus, Type 2 - genetics Female Genetic Variation Genotype Hispanic Americans HMGA1a Protein - genetics Humans Insulin Resistance - genetics Lipids - blood Lipoproteins - blood Male Mexico Middle Aged Receptor, Insulin - genetics Retrospective Studies
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