Micropit surfaces designed for accelerating osteogenic differentiation of murine mesenchymal stem cells via enhancing focal adhesion and actin polymerization

Abstract Recent reports demonstrate that enhanced focal adhesion (FA) between cells and the extracellular matrix (ECM) and intracellular actin polymerization (AP) upregulates cellular functions such as proliferation, stem-cell fate and differentiation. Purposed to accelerate osteogenic differentiati...

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Veröffentlicht in:Biomaterials 2014-02, Vol.35 (7), p.2245-2252
Hauptverfasser: Seo, Chang Ho, Jeong, Heonuk, Feng, Yue, Montagne, Kevin, Ushida, Takashi, Suzuki, Yuji, Furukawa, Katsuko S
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Sprache:eng
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