Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies
Abstract Adrenal diseases—including disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyperaldosteronism and congenital adrenal hyperplasia—are relatively rare in pregnancy, but a timely diagnosis and proper treatment are critical because these disorders ca...
Gespeichert in:
| Veröffentlicht in: | The American journal of the medical sciences 2014-01, Vol.347 (1), p.64-73 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 73 |
|---|---|
| container_issue | 1 |
| container_start_page | 64 |
| container_title | The American journal of the medical sciences |
| container_volume | 347 |
| creator | Kamoun, Mahdi, MD Mnif, Mouna F., PhD Charfi, Nadia, PhD Kacem, Faten H., MD Naceur, Basma B., MD Mnif, Fatma, PhD Dammak, Mohamed, MD Rekik, Nabila, PhD Abid, Mohamed, PhD |
| description | Abstract Adrenal diseases—including disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyperaldosteronism and congenital adrenal hyperplasia—are relatively rare in pregnancy, but a timely diagnosis and proper treatment are critical because these disorders can cause maternal and fetal morbidity and mortality. Making the diagnosis of adrenal disorders in pregnancy is challenging as symptoms associated with pregnancy are also seen in adrenal diseases. in addition, pregnancy is marked by several endocrine changes, including activation of the renin-angiotensin-aldosterone system and the hypothalamic-pituitary-adrenal axis. The aim of this article was to review the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy. |
| doi_str_mv | 10.1097/MAJ.0b013e31828aaeee |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1490745673</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002962915304389</els_id><sourcerecordid>1490745673</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466e-2089df21e202f7095b3ecfb83bec08fd18f0cbad8795a32c9fe18d70fe8d55d23</originalsourceid><addsrcrecordid>eNqVkktv1DAUhSMEotPCP0AoSxakXNt52CyQRi3loVZUKoil5dg3Gbcee7ATqvx7PJrCgg1i5c13zpU-n6J4QeCUgOjeXK0_n0IPhCEjnHKlEPFRsSIN4xUVAh4XKwCglWipOCqOU7oFIJQT9rQ4oqwhdduRVfF9bSJ65cpzm1AlTOX5HK0fy-uIo1deL2_LazVtwm6zJBtcGJfXmVWjD8mmUnlTXimvRtyin8qbKaoJR4vpWfFkUC7h84f3pPh28f7r2cfq8suHT2fry0rXbYsVBS7MQAlSoEMHoukZ6qHnrEcNfDCED6B7ZXgnGsWoFgMSbjoYkJumMZSdFK8OvbsYfsyYJrm1SaNzymOYkyS1gK5u2o5ltD6gOoaUIg5yF-1WxUUSkHulMiuVfyvNsZcPF-Z-i-ZP6LfDDPADcB_chDHdufkeo9ygctPmX93vDlHMin7anEraotdobEQ9SRPs_xZoZ73Vyt3hguk2zDF_btYgE5Ugb_aL2A8irwRqxgX7Ba-OsTc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1490745673</pqid></control><display><type>article</type><title>Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies</title><source>Journals@Ovid Ovid Autoload</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Kamoun, Mahdi, MD ; Mnif, Mouna F., PhD ; Charfi, Nadia, PhD ; Kacem, Faten H., MD ; Naceur, Basma B., MD ; Mnif, Fatma, PhD ; Dammak, Mohamed, MD ; Rekik, Nabila, PhD ; Abid, Mohamed, PhD</creator><creatorcontrib>Kamoun, Mahdi, MD ; Mnif, Mouna F., PhD ; Charfi, Nadia, PhD ; Kacem, Faten H., MD ; Naceur, Basma B., MD ; Mnif, Fatma, PhD ; Dammak, Mohamed, MD ; Rekik, Nabila, PhD ; Abid, Mohamed, PhD</creatorcontrib><description>Abstract Adrenal diseases—including disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyperaldosteronism and congenital adrenal hyperplasia—are relatively rare in pregnancy, but a timely diagnosis and proper treatment are critical because these disorders can cause maternal and fetal morbidity and mortality. Making the diagnosis of adrenal disorders in pregnancy is challenging as symptoms associated with pregnancy are also seen in adrenal diseases. in addition, pregnancy is marked by several endocrine changes, including activation of the renin-angiotensin-aldosterone system and the hypothalamic-pituitary-adrenal axis. The aim of this article was to review the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy.</description><identifier>ISSN: 0002-9629</identifier><identifier>EISSN: 1538-2990</identifier><identifier>DOI: 10.1097/MAJ.0b013e31828aaeee</identifier><identifier>PMID: 23514671</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Addison Disease - diagnosis ; Addison Disease - physiopathology ; Addison Disease - therapy ; Adrenal Gland Diseases - diagnosis ; Adrenal Gland Diseases - physiopathology ; Adrenal Gland Diseases - therapy ; Adrenal Gland Neoplasms - diagnosis ; Adrenal Gland Neoplasms - physiopathology ; Adrenal Gland Neoplasms - therapy ; Adrenal insufficiency ; Congenital adrenal hyperplasia ; Cushing Syndrome - diagnosis ; Cushing Syndrome - physiopathology ; Cushing Syndrome - therapy ; Cushing's syndrome ; Disease Management ; Female ; Humans ; Hypothalamo-Hypophyseal System - physiopathology ; Internal Medicine ; Pheochromocytoma ; Pheochromocytoma - diagnosis ; Pheochromocytoma - physiopathology ; Pheochromocytoma - therapy ; Pituitary-Adrenal System - physiopathology ; Pregnancy ; Pregnancy adrenal disease ; Pregnancy Complications - diagnosis ; Pregnancy Complications - physiopathology ; Pregnancy Complications - therapy ; Primary hyperaldosteronism ; Renin-Angiotensin System - physiology</subject><ispartof>The American journal of the medical sciences, 2014-01, Vol.347 (1), p.64-73</ispartof><rights>Southern Society for Clinical Investigation</rights><rights>2013 Southern Society for Clinical Investigation</rights><rights>Copyright © 2014 by the Southern Society for Clinical Investigation.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466e-2089df21e202f7095b3ecfb83bec08fd18f0cbad8795a32c9fe18d70fe8d55d23</citedby><cites>FETCH-LOGICAL-c466e-2089df21e202f7095b3ecfb83bec08fd18f0cbad8795a32c9fe18d70fe8d55d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23514671$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamoun, Mahdi, MD</creatorcontrib><creatorcontrib>Mnif, Mouna F., PhD</creatorcontrib><creatorcontrib>Charfi, Nadia, PhD</creatorcontrib><creatorcontrib>Kacem, Faten H., MD</creatorcontrib><creatorcontrib>Naceur, Basma B., MD</creatorcontrib><creatorcontrib>Mnif, Fatma, PhD</creatorcontrib><creatorcontrib>Dammak, Mohamed, MD</creatorcontrib><creatorcontrib>Rekik, Nabila, PhD</creatorcontrib><creatorcontrib>Abid, Mohamed, PhD</creatorcontrib><title>Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies</title><title>The American journal of the medical sciences</title><addtitle>Am J Med Sci</addtitle><description>Abstract Adrenal diseases—including disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyperaldosteronism and congenital adrenal hyperplasia—are relatively rare in pregnancy, but a timely diagnosis and proper treatment are critical because these disorders can cause maternal and fetal morbidity and mortality. Making the diagnosis of adrenal disorders in pregnancy is challenging as symptoms associated with pregnancy are also seen in adrenal diseases. in addition, pregnancy is marked by several endocrine changes, including activation of the renin-angiotensin-aldosterone system and the hypothalamic-pituitary-adrenal axis. The aim of this article was to review the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy.</description><subject>Addison Disease - diagnosis</subject><subject>Addison Disease - physiopathology</subject><subject>Addison Disease - therapy</subject><subject>Adrenal Gland Diseases - diagnosis</subject><subject>Adrenal Gland Diseases - physiopathology</subject><subject>Adrenal Gland Diseases - therapy</subject><subject>Adrenal Gland Neoplasms - diagnosis</subject><subject>Adrenal Gland Neoplasms - physiopathology</subject><subject>Adrenal Gland Neoplasms - therapy</subject><subject>Adrenal insufficiency</subject><subject>Congenital adrenal hyperplasia</subject><subject>Cushing Syndrome - diagnosis</subject><subject>Cushing Syndrome - physiopathology</subject><subject>Cushing Syndrome - therapy</subject><subject>Cushing's syndrome</subject><subject>Disease Management</subject><subject>Female</subject><subject>Humans</subject><subject>Hypothalamo-Hypophyseal System - physiopathology</subject><subject>Internal Medicine</subject><subject>Pheochromocytoma</subject><subject>Pheochromocytoma - diagnosis</subject><subject>Pheochromocytoma - physiopathology</subject><subject>Pheochromocytoma - therapy</subject><subject>Pituitary-Adrenal System - physiopathology</subject><subject>Pregnancy</subject><subject>Pregnancy adrenal disease</subject><subject>Pregnancy Complications - diagnosis</subject><subject>Pregnancy Complications - physiopathology</subject><subject>Pregnancy Complications - therapy</subject><subject>Primary hyperaldosteronism</subject><subject>Renin-Angiotensin System - physiology</subject><issn>0002-9629</issn><issn>1538-2990</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkktv1DAUhSMEotPCP0AoSxakXNt52CyQRi3loVZUKoil5dg3Gbcee7ATqvx7PJrCgg1i5c13zpU-n6J4QeCUgOjeXK0_n0IPhCEjnHKlEPFRsSIN4xUVAh4XKwCglWipOCqOU7oFIJQT9rQ4oqwhdduRVfF9bSJ65cpzm1AlTOX5HK0fy-uIo1deL2_LazVtwm6zJBtcGJfXmVWjD8mmUnlTXimvRtyin8qbKaoJR4vpWfFkUC7h84f3pPh28f7r2cfq8suHT2fry0rXbYsVBS7MQAlSoEMHoukZ6qHnrEcNfDCED6B7ZXgnGsWoFgMSbjoYkJumMZSdFK8OvbsYfsyYJrm1SaNzymOYkyS1gK5u2o5ltD6gOoaUIg5yF-1WxUUSkHulMiuVfyvNsZcPF-Z-i-ZP6LfDDPADcB_chDHdufkeo9ygctPmX93vDlHMin7anEraotdobEQ9SRPs_xZoZ73Vyt3hguk2zDF_btYgE5Ugb_aL2A8irwRqxgX7Ba-OsTc</recordid><startdate>201401</startdate><enddate>201401</enddate><creator>Kamoun, Mahdi, MD</creator><creator>Mnif, Mouna F., PhD</creator><creator>Charfi, Nadia, PhD</creator><creator>Kacem, Faten H., MD</creator><creator>Naceur, Basma B., MD</creator><creator>Mnif, Fatma, PhD</creator><creator>Dammak, Mohamed, MD</creator><creator>Rekik, Nabila, PhD</creator><creator>Abid, Mohamed, PhD</creator><general>Elsevier Inc</general><general>Copyright by the Southern Society for Clinical Investigation</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201401</creationdate><title>Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies</title><author>Kamoun, Mahdi, MD ; Mnif, Mouna F., PhD ; Charfi, Nadia, PhD ; Kacem, Faten H., MD ; Naceur, Basma B., MD ; Mnif, Fatma, PhD ; Dammak, Mohamed, MD ; Rekik, Nabila, PhD ; Abid, Mohamed, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466e-2089df21e202f7095b3ecfb83bec08fd18f0cbad8795a32c9fe18d70fe8d55d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Addison Disease - diagnosis</topic><topic>Addison Disease - physiopathology</topic><topic>Addison Disease - therapy</topic><topic>Adrenal Gland Diseases - diagnosis</topic><topic>Adrenal Gland Diseases - physiopathology</topic><topic>Adrenal Gland Diseases - therapy</topic><topic>Adrenal Gland Neoplasms - diagnosis</topic><topic>Adrenal Gland Neoplasms - physiopathology</topic><topic>Adrenal Gland Neoplasms - therapy</topic><topic>Adrenal insufficiency</topic><topic>Congenital adrenal hyperplasia</topic><topic>Cushing Syndrome - diagnosis</topic><topic>Cushing Syndrome - physiopathology</topic><topic>Cushing Syndrome - therapy</topic><topic>Cushing's syndrome</topic><topic>Disease Management</topic><topic>Female</topic><topic>Humans</topic><topic>Hypothalamo-Hypophyseal System - physiopathology</topic><topic>Internal Medicine</topic><topic>Pheochromocytoma</topic><topic>Pheochromocytoma - diagnosis</topic><topic>Pheochromocytoma - physiopathology</topic><topic>Pheochromocytoma - therapy</topic><topic>Pituitary-Adrenal System - physiopathology</topic><topic>Pregnancy</topic><topic>Pregnancy adrenal disease</topic><topic>Pregnancy Complications - diagnosis</topic><topic>Pregnancy Complications - physiopathology</topic><topic>Pregnancy Complications - therapy</topic><topic>Primary hyperaldosteronism</topic><topic>Renin-Angiotensin System - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamoun, Mahdi, MD</creatorcontrib><creatorcontrib>Mnif, Mouna F., PhD</creatorcontrib><creatorcontrib>Charfi, Nadia, PhD</creatorcontrib><creatorcontrib>Kacem, Faten H., MD</creatorcontrib><creatorcontrib>Naceur, Basma B., MD</creatorcontrib><creatorcontrib>Mnif, Fatma, PhD</creatorcontrib><creatorcontrib>Dammak, Mohamed, MD</creatorcontrib><creatorcontrib>Rekik, Nabila, PhD</creatorcontrib><creatorcontrib>Abid, Mohamed, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of the medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamoun, Mahdi, MD</au><au>Mnif, Mouna F., PhD</au><au>Charfi, Nadia, PhD</au><au>Kacem, Faten H., MD</au><au>Naceur, Basma B., MD</au><au>Mnif, Fatma, PhD</au><au>Dammak, Mohamed, MD</au><au>Rekik, Nabila, PhD</au><au>Abid, Mohamed, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies</atitle><jtitle>The American journal of the medical sciences</jtitle><addtitle>Am J Med Sci</addtitle><date>2014-01</date><risdate>2014</risdate><volume>347</volume><issue>1</issue><spage>64</spage><epage>73</epage><pages>64-73</pages><issn>0002-9629</issn><eissn>1538-2990</eissn><abstract>Abstract Adrenal diseases—including disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyperaldosteronism and congenital adrenal hyperplasia—are relatively rare in pregnancy, but a timely diagnosis and proper treatment are critical because these disorders can cause maternal and fetal morbidity and mortality. Making the diagnosis of adrenal disorders in pregnancy is challenging as symptoms associated with pregnancy are also seen in adrenal diseases. in addition, pregnancy is marked by several endocrine changes, including activation of the renin-angiotensin-aldosterone system and the hypothalamic-pituitary-adrenal axis. The aim of this article was to review the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>23514671</pmid><doi>10.1097/MAJ.0b013e31828aaeee</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9629 |
| ispartof | The American journal of the medical sciences, 2014-01, Vol.347 (1), p.64-73 |
| issn | 0002-9629 1538-2990 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1490745673 |
| source | Journals@Ovid Ovid Autoload; MEDLINE; Alma/SFX Local Collection |
| subjects | Addison Disease - diagnosis Addison Disease - physiopathology Addison Disease - therapy Adrenal Gland Diseases - diagnosis Adrenal Gland Diseases - physiopathology Adrenal Gland Diseases - therapy Adrenal Gland Neoplasms - diagnosis Adrenal Gland Neoplasms - physiopathology Adrenal Gland Neoplasms - therapy Adrenal insufficiency Congenital adrenal hyperplasia Cushing Syndrome - diagnosis Cushing Syndrome - physiopathology Cushing Syndrome - therapy Cushing's syndrome Disease Management Female Humans Hypothalamo-Hypophyseal System - physiopathology Internal Medicine Pheochromocytoma Pheochromocytoma - diagnosis Pheochromocytoma - physiopathology Pheochromocytoma - therapy Pituitary-Adrenal System - physiopathology Pregnancy Pregnancy adrenal disease Pregnancy Complications - diagnosis Pregnancy Complications - physiopathology Pregnancy Complications - therapy Primary hyperaldosteronism Renin-Angiotensin System - physiology |
| title | Adrenal Diseases During Pregnancy: Pathophysiology, Diagnosis and Management Strategies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T07%3A16%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adrenal%20Diseases%20During%20Pregnancy:%20Pathophysiology,%20Diagnosis%20and%20Management%20Strategies&rft.jtitle=The%20American%20journal%20of%20the%20medical%20sciences&rft.au=Kamoun,%20Mahdi,%20MD&rft.date=2014-01&rft.volume=347&rft.issue=1&rft.spage=64&rft.epage=73&rft.pages=64-73&rft.issn=0002-9629&rft.eissn=1538-2990&rft_id=info:doi/10.1097/MAJ.0b013e31828aaeee&rft_dat=%3Cproquest_cross%3E1490745673%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1490745673&rft_id=info:pmid/23514671&rft_els_id=1_s2_0_S0002962915304389&rfr_iscdi=true |