Enzymatic pH control for biomimetic deposition of calcium phosphate coatings

The current study examines the enzymatic decomposition of urea into carbon dioxide and ammonia as a means to increase the pH during biomimetic deposition of calcium phospate (CaP) onto implant surfaces. The kinetics of the enzymatically induced pH increase were studied by monitoring pH, calcium conc...

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Veröffentlicht in:	Acta biomaterialia 2014-02, Vol.10 (2), p.931-939
Hauptverfasser:	Nijhuis, Arnold W.G., Nejadnik, M. Reza, Nudelman, Fabio, Walboomers, X. Frank, te Riet, Joost, Habibovic, Pamela, Tahmasebi Birgani, Zeinab, Li, Yubao, Bomans, Paul H.H., Jansen, John A., Sommerdijk, Nico A.J.M., Leeuwenburgh, Sander C.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomimetic Materials - chemistry Calcification Calcium - analysis Calcium phosphate coating Calcium Phosphates - chemistry Coated Materials, Biocompatible - chemistry Cryoelectron Microscopy Electric Conductivity Hydrogen-Ion Concentration Hydroxyapatite Patterned surfaces Phosphates - analysis Polystyrenes - chemistry Pre-nucleation clusters Spectroscopy, Fourier Transform Infrared Titanium - chemistry Urease - metabolism X-Ray Diffraction
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