Single nucleotide polymorphisms in arrhythmia genes modify the risk of cardiac events and sudden death in long QT syndrome

Background Disease-modifying single nucleotide polymorphisms (SNPs) can help explain incomplete penetrance and variable expressivity in congenital long QT syndrome (LQTS) by altering susceptibility to arrhythmias. Objective The purpose of this study was to assess multiple arrhythmia SNPs (in 16 gene...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Heart rhythm 2014, Vol.11 (1), p.76-82
Hauptverfasser:	Earle, Nikki, BSc (Hons), Yeo Han, Dug, PhD, Pilbrow, Anna, PhD, Crawford, Jackie, NZCS, Smith, Warren, FRACP, Shelling, Andrew N., PhD, Cameron, Vicky, PhD, Love, Donald R., PhD, Skinner, Jonathan R., FRACP, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alleles Arrhythmia Cardiovascular Death, Sudden, Cardiac - epidemiology Death, Sudden, Cardiac - etiology DNA - genetics Electrocardiography Female Genetics Genotype Humans Long QT syndrome Long QT Syndrome - complications Long QT Syndrome - genetics Long QT Syndrome - mortality Male Middle Aged New Zealand - epidemiology Polymorphism, Single Nucleotide Risk Factors Single nucleotide polymorphisms Sudden cardiac death Survival Rate - trends Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!