Bactericidal/permeability-increasing protein in host defense and its efficacy in the treatment of bacterial sepsis

The 55-kD bactericidal/permeability-increasing protein (BPI) is a neutrophil-derived polypeptide belonging to a family of lipid and endotoxin binding proteins. BPI is composed of two functionally distinct structural domains: a potently antibacterial and antiendotoxin ∼ 20-kD aminoterminal half, and...

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Veröffentlicht in:Current infectious disease reports 2007-10, Vol.3 (5), p.407-412
Hauptverfasser: Levy, Ofer, Elsbach, Peter
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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