Amidase encapsulated O-carboxymethyl chitosan nanoparticles for vaccine delivery

•Amidase encapsulated O-carboxymethyl chitosan nanoparticles were developed.•These nanoparticles were found to be hemo- and cyto-compatible.•A sustained release of amidase from O-CMC nanoparticles was observed.•This sustained release of amidase would prolong its immunogenicity.•These Ami-O-CMC nanop...

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Veröffentlicht in:	International journal of biological macromolecules 2014-02, Vol.63, p.154-157
Hauptverfasser:	Smitha, K.T., Sreelakshmi, M., Nisha, N., Jayakumar, R., Biswas, Raja
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidase encapsulation Amidohydrolases - chemistry Chitosan - administration & dosage Chitosan - analogs & derivatives Chitosan - chemistry Drug Delivery Systems Humans Immunogenicity Immunotherapy, Active Nanoparticles - administration & dosage Nanoparticles - chemistry Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcal Infections - pathology Staphylococcus aureus Staphylococcus aureus - drug effects
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