Crystalline keratopathy due to kappa chains in a monoclonal gammopathy
The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this impor...
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| Veröffentlicht in: | Archivos de la Sociedad Española de Oftalmología 2013-12, Vol.88 (12), p.489-492 |
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| container_title | Archivos de la Sociedad Española de Oftalmología |
| container_volume | 88 |
| creator | Mesa-Gutiérrez, J C Rouras-López, A Amías-Lamana, V Hoyos-Chacón, J Cabiró-Badimón, I Porta-Monnet, J |
| description | The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this important association.
Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy. |
| doi_str_mv | 10.1016/j.oftal.2012.06.019 |
| format | Article |
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Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy.</description><identifier>EISSN: 1989-7286</identifier><identifier>DOI: 10.1016/j.oftal.2012.06.019</identifier><identifier>PMID: 24257260</identifier><language>spa</language><publisher>Spain</publisher><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Bence Jones Protein - urine ; Combined Modality Therapy ; Corneal Opacity - diagnosis ; Corneal Opacity - etiology ; Corneal Opacity - pathology ; Crystallization ; Cyclophosphamide - administration & dosage ; Diagnosis, Differential ; Hematopoietic Stem Cell Transplantation ; Humans ; Immunoglobulin kappa-Chains - analysis ; Kidney Failure, Chronic - etiology ; Male ; Melphalan - administration & dosage ; Middle Aged ; Paraproteinemias - complications ; Paraproteinemias - diagnosis ; Paraproteinemias - therapy ; Paraproteinemias - urine ; Paraproteins - analysis ; Phacoemulsification ; Postoperative Complications - diagnosis ; Prednisone - administration & dosage ; Slit Lamp ; Thalidomide - administration & dosage ; Thalidomide - analogs & derivatives</subject><ispartof>Archivos de la Sociedad Española de Oftalmología, 2013-12, Vol.88 (12), p.489-492</ispartof><rights>Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24257260$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mesa-Gutiérrez, J C</creatorcontrib><creatorcontrib>Rouras-López, A</creatorcontrib><creatorcontrib>Amías-Lamana, V</creatorcontrib><creatorcontrib>Hoyos-Chacón, J</creatorcontrib><creatorcontrib>Cabiró-Badimón, I</creatorcontrib><creatorcontrib>Porta-Monnet, J</creatorcontrib><title>Crystalline keratopathy due to kappa chains in a monoclonal gammopathy</title><title>Archivos de la Sociedad Española de Oftalmología</title><addtitle>Arch Soc Esp Oftalmol</addtitle><description>The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this important association.
Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy.</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Bence Jones Protein - urine</subject><subject>Combined Modality Therapy</subject><subject>Corneal Opacity - diagnosis</subject><subject>Corneal Opacity - etiology</subject><subject>Corneal Opacity - pathology</subject><subject>Crystallization</subject><subject>Cyclophosphamide - administration & dosage</subject><subject>Diagnosis, Differential</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Humans</subject><subject>Immunoglobulin kappa-Chains - analysis</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Male</subject><subject>Melphalan - administration & dosage</subject><subject>Middle Aged</subject><subject>Paraproteinemias - complications</subject><subject>Paraproteinemias - diagnosis</subject><subject>Paraproteinemias - therapy</subject><subject>Paraproteinemias - urine</subject><subject>Paraproteins - analysis</subject><subject>Phacoemulsification</subject><subject>Postoperative Complications - diagnosis</subject><subject>Prednisone - administration & dosage</subject><subject>Slit Lamp</subject><subject>Thalidomide - administration & dosage</subject><subject>Thalidomide - analogs & derivatives</subject><issn>1989-7286</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z71OwzAUBWALCdFSeAIk5JElwddx7HhEFQWkSizdoxv_0LROHOJk6NtTqWU6y3eOdAh5ApYDA_l6yKOfMOScAc-ZzBnoG7IEXelM8UouyH1KB8ZEUejqjiy44KXiki3JZj2e0rkZ2t7RoxtxigNO-xO1s6NTpEccBqRmj22faNtTpF3sowmxx0B_sOsu_IHcegzJPV5zRXab9936M9t-f3yt37bZUEqWGYOFsaxw2LjGWs7Bc4EcrbUetTJlI6xjjdVcOy9RSvTolW8AhPLKiWJFXi6zwxh_Z5emumuTcSFg7-KcahCaKeAA5Zk-X-ncdM7Ww9h2OJ7q_-vFH13DXQ4</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Mesa-Gutiérrez, J C</creator><creator>Rouras-López, A</creator><creator>Amías-Lamana, V</creator><creator>Hoyos-Chacón, J</creator><creator>Cabiró-Badimón, I</creator><creator>Porta-Monnet, J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201312</creationdate><title>Crystalline keratopathy due to kappa chains in a monoclonal gammopathy</title><author>Mesa-Gutiérrez, J C ; 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Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy.</abstract><cop>Spain</cop><pmid>24257260</pmid><doi>10.1016/j.oftal.2012.06.019</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1989-7286 |
| ispartof | Archivos de la Sociedad Española de Oftalmología, 2013-12, Vol.88 (12), p.489-492 |
| issn | 1989-7286 |
| language | spa |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bence Jones Protein - urine Combined Modality Therapy Corneal Opacity - diagnosis Corneal Opacity - etiology Corneal Opacity - pathology Crystallization Cyclophosphamide - administration & dosage Diagnosis, Differential Hematopoietic Stem Cell Transplantation Humans Immunoglobulin kappa-Chains - analysis Kidney Failure, Chronic - etiology Male Melphalan - administration & dosage Middle Aged Paraproteinemias - complications Paraproteinemias - diagnosis Paraproteinemias - therapy Paraproteinemias - urine Paraproteins - analysis Phacoemulsification Postoperative Complications - diagnosis Prednisone - administration & dosage Slit Lamp Thalidomide - administration & dosage Thalidomide - analogs & derivatives |
| title | Crystalline keratopathy due to kappa chains in a monoclonal gammopathy |
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