Why does the bone marrow fail in Fanconi anemia?

The inherited bone marrow failure (BMF) syndromes are a rare and diverse group of genetic disorders that ultimately result in the loss of blood production. The molecular defects underlying many of these conditions have been elucidated, and great progress has been made toward understanding the normal...

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Veröffentlicht in:	Blood 2014-01, Vol.123 (1), p.26-34
Hauptverfasser:	Garaycoechea, Juan I., Patel, K.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow - physiopathology Bone Marrow Diseases - genetics Bone Marrow Diseases - physiopathology Bone Marrow Transplantation - methods Cross-Linking Reagents - chemistry DNA Damage DNA Repair Fanconi Anemia - genetics Fanconi Anemia - physiopathology Fanconi Anemia Complementation Group Proteins - genetics Fanconi Anemia Complementation Group Proteins - physiology Humans Mice Stem Cells - cytology
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