Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study

Summary Objectives The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design This study included...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Osteoarthritis and cartilage 2014-01, Vol.22 (1), p.104-110
Hauptverfasser: Teraguchi, M, Yoshimura, N, Hashizume, H, Muraki, S, Yamada, H, Minamide, A, Oka, H, Ishimoto, Y, Nagata, K, Kagotani, R, Takiguchi, N, Akune, T, Kawaguchi, H, Nakamura, K, Yoshida, M
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 110
container_issue 1
container_start_page 104
container_title Osteoarthritis and cartilage
container_volume 22
creator Teraguchi, M
Yoshimura, N
Hashizume, H
Muraki, S
Yamada, H
Minamide, A
Oka, H
Ishimoto, Y
Nagata, K
Kagotani, R
Takiguchi, N
Akune, T
Kawaguchi, H
Nakamura, K
Yoshida, M
description Summary Objectives The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design This study included 975 participants (324 men, mean age of 67.2 years; 651 women, mean age of 66.0 years) with an age range of 21–97 years in the Wakayama Spine Study. DD on MRI was classified into Pfirrmann's system (grades 4 and 5 indicating DD). We assessed the prevalence of DD at each level in the cervical, thoracic, and lumbar regions and the entire spine, and examined DD-associated factors and symptoms. Results The prevalence of DD over the entire spine was 71% in men and 77% in women aged 90% in both men and women aged >50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). Age and obesity were associated with the presence of DD in all regions. Low back pain was associated with the presence of DD in the lumbar region. Conclusion The current study established the baseline data of DD over the entire spine in a large population of elderly individuals. These data provide the foundation for elucidating the causes and mechanisms of DD.
doi_str_mv 10.1016/j.joca.2013.10.019
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1490702542</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1063458413010029</els_id><sourcerecordid>1490702542</sourcerecordid><originalsourceid>FETCH-LOGICAL-c529t-8ec3da5a17c2e35c79b8f5d05d844e9d881690cfc6f5bcac739324789952b6df3</originalsourceid><addsrcrecordid>eNp9ks2KFDEUhYMoztj6Ai4kSzfV5qdSVRERhsE_GFBoxWVIJbec1FQnZZJq6HfwoU11jy5cuEq49zsX7jkXoeeUbCmhzatxOwajt4xQXgpbQuUDdEkFY5VsBH9Y_qThVS26-gI9SWkkhHBKyWN0wWrGpaz5Jfr1JcJBT-ANYO0tti7l6Polu-BxGLDzGeIBYoY-6mltG2zhB3iI-syUJs63gMFnFwGn2XkoMqzxHOZlOlFVrxNYbMJtiPn1Cf-u7_RR7zXenQS7vNjjU_Ro0FOCZ_fvBn17_-7r9cfq5vOHT9dXN5URTOaqA8OtFpq2hgEXppV9NwhLhO3qGqTtOtpIYgbTDKI32rRccla3nZSC9Y0d-Aa9PM-dY_i5QMpqX_aCadIewpIUrSVpCRPFpQ1iZ9TEkFKEQc3R7XU8KkrUmoIa1ZqCWlNYayWFInpxP3_p92D_Sv7YXoA3ZwDKlgcHUSXj1gxssdBkZYP7__y3_8jN5LwzerqDI6QxLNEX_xRViSmidusdrGdAOaGEMMl_A9d3sDs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1490702542</pqid></control><display><type>article</type><title>Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Teraguchi, M ; Yoshimura, N ; Hashizume, H ; Muraki, S ; Yamada, H ; Minamide, A ; Oka, H ; Ishimoto, Y ; Nagata, K ; Kagotani, R ; Takiguchi, N ; Akune, T ; Kawaguchi, H ; Nakamura, K ; Yoshida, M</creator><creatorcontrib>Teraguchi, M ; Yoshimura, N ; Hashizume, H ; Muraki, S ; Yamada, H ; Minamide, A ; Oka, H ; Ishimoto, Y ; Nagata, K ; Kagotani, R ; Takiguchi, N ; Akune, T ; Kawaguchi, H ; Nakamura, K ; Yoshida, M</creatorcontrib><description>Summary Objectives The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design This study included 975 participants (324 men, mean age of 67.2 years; 651 women, mean age of 66.0 years) with an age range of 21–97 years in the Wakayama Spine Study. DD on MRI was classified into Pfirrmann's system (grades 4 and 5 indicating DD). We assessed the prevalence of DD at each level in the cervical, thoracic, and lumbar regions and the entire spine, and examined DD-associated factors and symptoms. Results The prevalence of DD over the entire spine was 71% in men and 77% in women aged &lt;50 years, and &gt;90% in both men and women aged &gt;50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). Age and obesity were associated with the presence of DD in all regions. Low back pain was associated with the presence of DD in the lumbar region. Conclusion The current study established the baseline data of DD over the entire spine in a large population of elderly individuals. These data provide the foundation for elucidating the causes and mechanisms of DD.</description><identifier>ISSN: 1063-4584</identifier><identifier>EISSN: 1522-9653</identifier><identifier>DOI: 10.1016/j.joca.2013.10.019</identifier><identifier>PMID: 24239943</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Body Mass Index ; Cervical Vertebrae - pathology ; Cohort Studies ; Distribution ; Entire spine ; Female ; Humans ; Intervertebral disc degeneration ; Intervertebral Disc Degeneration - epidemiology ; Intervertebral Disc Degeneration - etiology ; Intervertebral Disc Degeneration - pathology ; Japan - epidemiology ; Low Back Pain - epidemiology ; Low Back Pain - etiology ; Lumbar Vertebrae - pathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Obesity - complications ; Obesity - epidemiology ; Population-based cohort ; Prevalence ; Rheumatology ; Severity of Illness Index ; Sex Distribution ; Thoracic Vertebrae - pathology ; Young Adult</subject><ispartof>Osteoarthritis and cartilage, 2014-01, Vol.22 (1), p.104-110</ispartof><rights>Osteoarthritis Research Society International</rights><rights>2013 Osteoarthritis Research Society International</rights><rights>Copyright © 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c529t-8ec3da5a17c2e35c79b8f5d05d844e9d881690cfc6f5bcac739324789952b6df3</citedby><cites>FETCH-LOGICAL-c529t-8ec3da5a17c2e35c79b8f5d05d844e9d881690cfc6f5bcac739324789952b6df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1063458413010029$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24239943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Teraguchi, M</creatorcontrib><creatorcontrib>Yoshimura, N</creatorcontrib><creatorcontrib>Hashizume, H</creatorcontrib><creatorcontrib>Muraki, S</creatorcontrib><creatorcontrib>Yamada, H</creatorcontrib><creatorcontrib>Minamide, A</creatorcontrib><creatorcontrib>Oka, H</creatorcontrib><creatorcontrib>Ishimoto, Y</creatorcontrib><creatorcontrib>Nagata, K</creatorcontrib><creatorcontrib>Kagotani, R</creatorcontrib><creatorcontrib>Takiguchi, N</creatorcontrib><creatorcontrib>Akune, T</creatorcontrib><creatorcontrib>Kawaguchi, H</creatorcontrib><creatorcontrib>Nakamura, K</creatorcontrib><creatorcontrib>Yoshida, M</creatorcontrib><title>Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study</title><title>Osteoarthritis and cartilage</title><addtitle>Osteoarthritis Cartilage</addtitle><description>Summary Objectives The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design This study included 975 participants (324 men, mean age of 67.2 years; 651 women, mean age of 66.0 years) with an age range of 21–97 years in the Wakayama Spine Study. DD on MRI was classified into Pfirrmann's system (grades 4 and 5 indicating DD). We assessed the prevalence of DD at each level in the cervical, thoracic, and lumbar regions and the entire spine, and examined DD-associated factors and symptoms. Results The prevalence of DD over the entire spine was 71% in men and 77% in women aged &lt;50 years, and &gt;90% in both men and women aged &gt;50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). Age and obesity were associated with the presence of DD in all regions. Low back pain was associated with the presence of DD in the lumbar region. Conclusion The current study established the baseline data of DD over the entire spine in a large population of elderly individuals. These data provide the foundation for elucidating the causes and mechanisms of DD.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body Mass Index</subject><subject>Cervical Vertebrae - pathology</subject><subject>Cohort Studies</subject><subject>Distribution</subject><subject>Entire spine</subject><subject>Female</subject><subject>Humans</subject><subject>Intervertebral disc degeneration</subject><subject>Intervertebral Disc Degeneration - epidemiology</subject><subject>Intervertebral Disc Degeneration - etiology</subject><subject>Intervertebral Disc Degeneration - pathology</subject><subject>Japan - epidemiology</subject><subject>Low Back Pain - epidemiology</subject><subject>Low Back Pain - etiology</subject><subject>Lumbar Vertebrae - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Population-based cohort</subject><subject>Prevalence</subject><subject>Rheumatology</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Thoracic Vertebrae - pathology</subject><subject>Young Adult</subject><issn>1063-4584</issn><issn>1522-9653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks2KFDEUhYMoztj6Ai4kSzfV5qdSVRERhsE_GFBoxWVIJbec1FQnZZJq6HfwoU11jy5cuEq49zsX7jkXoeeUbCmhzatxOwajt4xQXgpbQuUDdEkFY5VsBH9Y_qThVS26-gI9SWkkhHBKyWN0wWrGpaz5Jfr1JcJBT-ANYO0tti7l6Polu-BxGLDzGeIBYoY-6mltG2zhB3iI-syUJs63gMFnFwGn2XkoMqzxHOZlOlFVrxNYbMJtiPn1Cf-u7_RR7zXenQS7vNjjU_Ro0FOCZ_fvBn17_-7r9cfq5vOHT9dXN5URTOaqA8OtFpq2hgEXppV9NwhLhO3qGqTtOtpIYgbTDKI32rRccla3nZSC9Y0d-Aa9PM-dY_i5QMpqX_aCadIewpIUrSVpCRPFpQ1iZ9TEkFKEQc3R7XU8KkrUmoIa1ZqCWlNYayWFInpxP3_p92D_Sv7YXoA3ZwDKlgcHUSXj1gxssdBkZYP7__y3_8jN5LwzerqDI6QxLNEX_xRViSmidusdrGdAOaGEMMl_A9d3sDs</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Teraguchi, M</creator><creator>Yoshimura, N</creator><creator>Hashizume, H</creator><creator>Muraki, S</creator><creator>Yamada, H</creator><creator>Minamide, A</creator><creator>Oka, H</creator><creator>Ishimoto, Y</creator><creator>Nagata, K</creator><creator>Kagotani, R</creator><creator>Takiguchi, N</creator><creator>Akune, T</creator><creator>Kawaguchi, H</creator><creator>Nakamura, K</creator><creator>Yoshida, M</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140101</creationdate><title>Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study</title><author>Teraguchi, M ; Yoshimura, N ; Hashizume, H ; Muraki, S ; Yamada, H ; Minamide, A ; Oka, H ; Ishimoto, Y ; Nagata, K ; Kagotani, R ; Takiguchi, N ; Akune, T ; Kawaguchi, H ; Nakamura, K ; Yoshida, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c529t-8ec3da5a17c2e35c79b8f5d05d844e9d881690cfc6f5bcac739324789952b6df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body Mass Index</topic><topic>Cervical Vertebrae - pathology</topic><topic>Cohort Studies</topic><topic>Distribution</topic><topic>Entire spine</topic><topic>Female</topic><topic>Humans</topic><topic>Intervertebral disc degeneration</topic><topic>Intervertebral Disc Degeneration - epidemiology</topic><topic>Intervertebral Disc Degeneration - etiology</topic><topic>Intervertebral Disc Degeneration - pathology</topic><topic>Japan - epidemiology</topic><topic>Low Back Pain - epidemiology</topic><topic>Low Back Pain - etiology</topic><topic>Lumbar Vertebrae - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Population-based cohort</topic><topic>Prevalence</topic><topic>Rheumatology</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Thoracic Vertebrae - pathology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Teraguchi, M</creatorcontrib><creatorcontrib>Yoshimura, N</creatorcontrib><creatorcontrib>Hashizume, H</creatorcontrib><creatorcontrib>Muraki, S</creatorcontrib><creatorcontrib>Yamada, H</creatorcontrib><creatorcontrib>Minamide, A</creatorcontrib><creatorcontrib>Oka, H</creatorcontrib><creatorcontrib>Ishimoto, Y</creatorcontrib><creatorcontrib>Nagata, K</creatorcontrib><creatorcontrib>Kagotani, R</creatorcontrib><creatorcontrib>Takiguchi, N</creatorcontrib><creatorcontrib>Akune, T</creatorcontrib><creatorcontrib>Kawaguchi, H</creatorcontrib><creatorcontrib>Nakamura, K</creatorcontrib><creatorcontrib>Yoshida, M</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Osteoarthritis and cartilage</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Teraguchi, M</au><au>Yoshimura, N</au><au>Hashizume, H</au><au>Muraki, S</au><au>Yamada, H</au><au>Minamide, A</au><au>Oka, H</au><au>Ishimoto, Y</au><au>Nagata, K</au><au>Kagotani, R</au><au>Takiguchi, N</au><au>Akune, T</au><au>Kawaguchi, H</au><au>Nakamura, K</au><au>Yoshida, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study</atitle><jtitle>Osteoarthritis and cartilage</jtitle><addtitle>Osteoarthritis Cartilage</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>22</volume><issue>1</issue><spage>104</spage><epage>110</epage><pages>104-110</pages><issn>1063-4584</issn><eissn>1522-9653</eissn><abstract>Summary Objectives The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design This study included 975 participants (324 men, mean age of 67.2 years; 651 women, mean age of 66.0 years) with an age range of 21–97 years in the Wakayama Spine Study. DD on MRI was classified into Pfirrmann's system (grades 4 and 5 indicating DD). We assessed the prevalence of DD at each level in the cervical, thoracic, and lumbar regions and the entire spine, and examined DD-associated factors and symptoms. Results The prevalence of DD over the entire spine was 71% in men and 77% in women aged &lt;50 years, and &gt;90% in both men and women aged &gt;50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). Age and obesity were associated with the presence of DD in all regions. Low back pain was associated with the presence of DD in the lumbar region. Conclusion The current study established the baseline data of DD over the entire spine in a large population of elderly individuals. These data provide the foundation for elucidating the causes and mechanisms of DD.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>24239943</pmid><doi>10.1016/j.joca.2013.10.019</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1063-4584
ispartof Osteoarthritis and cartilage, 2014-01, Vol.22 (1), p.104-110
issn 1063-4584
1522-9653
language eng
recordid cdi_proquest_miscellaneous_1490702542
source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Adult
Age Distribution
Aged
Aged, 80 and over
Body Mass Index
Cervical Vertebrae - pathology
Cohort Studies
Distribution
Entire spine
Female
Humans
Intervertebral disc degeneration
Intervertebral Disc Degeneration - epidemiology
Intervertebral Disc Degeneration - etiology
Intervertebral Disc Degeneration - pathology
Japan - epidemiology
Low Back Pain - epidemiology
Low Back Pain - etiology
Lumbar Vertebrae - pathology
Magnetic Resonance Imaging
Male
Middle Aged
Obesity - complications
Obesity - epidemiology
Population-based cohort
Prevalence
Rheumatology
Severity of Illness Index
Sex Distribution
Thoracic Vertebrae - pathology
Young Adult
title Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T02%3A25%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20and%20distribution%20of%20intervertebral%20disc%20degeneration%20over%20the%20entire%20spine%20in%20a%20population-based%20cohort:%20the%20Wakayama%20Spine%20Study&rft.jtitle=Osteoarthritis%20and%20cartilage&rft.au=Teraguchi,%20M&rft.date=2014-01-01&rft.volume=22&rft.issue=1&rft.spage=104&rft.epage=110&rft.pages=104-110&rft.issn=1063-4584&rft.eissn=1522-9653&rft_id=info:doi/10.1016/j.joca.2013.10.019&rft_dat=%3Cproquest_cross%3E1490702542%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1490702542&rft_id=info:pmid/24239943&rft_els_id=1_s2_0_S1063458413010029&rfr_iscdi=true