Interaction between TGF-β1 (869C/T) polymorphism and biochemical risk factor for prediction of disease progression in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease. Transforming growth factor-β1 (TGF-β1) may be a promising candidate gene for susceptibility and severity in RA. We aimed to determine whether TGF-β1 polymorphism is associated with susceptibility to RA and progression of joint destruction,...

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Veröffentlicht in:	Gene 2014-02, Vol.536 (2), p.393-397
Hauptverfasser:	Hussein, Yousri M., Mohamed, Randa H., El-Shahawy, Eman E., Alzahrani, Saad S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Arthritis, Rheumatoid - genetics Bone erosion C-Reactive Protein - genetics Disease Progression Genetic Predisposition to Disease - genetics Genotype Humans Middle Aged Osteoporosis Osteoporosis - genetics Polymorphism, Single Nucleotide - genetics Rheumatoid arthritis Risk Factors TGF-β1 Transforming Growth Factor beta1 - genetics
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