Genetic variability in deacetylation of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene in inbred strains of mice

Genetic variability in 2-acetylaminofluorene (AAF) and N-hydroxy-2-acetylaminofluorene (N-OH-AAF) deacetylase activities was examined in 19 inbred strains of mice. AAF deacetylase activities ranged from 0.60 to 1.33 nmol/min/mg protein, and there was an ˜2.5-fold difference in AAF deacetylase activi...

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Veröffentlicht in:	Carcinogenesis (New York) 1987-12, Vol.8 (12), p.1939-1941
Hauptverfasser:	Hultin, Theresa A., Weber, Wendell W.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetylaminofluorene - analogs & derivatives 2-Acetylaminofluorene - pharmacokinetics Amidohydrolases - metabolism Animals Biological and medical sciences Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Hydroxyacetylaminofluorene - pharmacokinetics Mice Mice, Inbred Strains - genetics Mice, Inbred Strains - metabolism Species Specificity Vertebrata
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