The labile nature of the insulin signal(s) for the stimulation of DNA synthesis in mouse lens epithelial and 3T3 cells

A kinetic study was carried out to assess the stability of the intracellular signal(s) generated by insulin in quiescent cells for the stimulation of DNA synthesis. Using murine lens epithelial cells and Swiss 3T3 cells in culture, it was found that insulin stimulated DNA synthesis after a lag of 14...

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Veröffentlicht in:	The Journal of biological chemistry 1987-01, Vol.262 (1), p.229-233
Hauptverfasser:	Reid, T W, Reid, W A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line Cell physiology DNA - biosynthesis Drug Synergism Epithelium - metabolism Fundamental and applied biological sciences. Psychology Hormonal regulation Insulin - metabolism Insulin - pharmacology Kinetics Lens, Crystalline - drug effects Lens, Crystalline - metabolism Mice Molecular and cellular biology Receptor, Insulin - metabolism Time Factors Vanadates Vanadium - pharmacology
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