The optimal morning:evening ratio in total dose of twice-daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24-week multi-centre prospective, randomized controlled, open-labelled clinical study

Aims Biphasic insulin analogues are widely used in patients with Type 2 diabetes mellitus suboptimally controlled on oral anti‐diabetic drugs. Several topics in this area remain controversial, including how to divide the daily dose of biphasic insulin analogue. We aimed to determine the optimal dosi...

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Veröffentlicht in:	Diabetic medicine 2014-01, Vol.31 (1), p.68-75
Hauptverfasser:	Jung, C. H., Park, J.-Y., Cho, J. H., Yoon, K.-H., Yang, H. K., Lee, Y.-H., Cha, B. S., Lee, B.-W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biphasic Insulins - administration & dosage Biphasic Insulins - pharmacokinetics Blood Glucose - drug effects Blood Glucose - metabolism Blood Glucose Self-Monitoring Diabetes Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetes. Impaired glucose tolerance Dose-Response Relationship, Drug Drug Administration Schedule Drug dosages Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Glycated Hemoglobin A - drug effects Glycated Hemoglobin A - metabolism Humans Hyperglycemia Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - pharmacokinetics Male Medical sciences Middle Aged Prospective Studies Republic of Korea Time Factors Treatment Outcome Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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