Imaging brain iron and diffusion patterns: a follow-up study of Parkinson's disease in the initial stages

The aim of this study was to examine changes of brain iron content and diffusion patterns longitudinally in early-stage Parkinson's disease (PD) patients using T2- and T2*-based magnetic resonance imaging (MRI) over 2-year follow-up. We imaged 32 PD patients with tremor and 19 healthy controls....

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Veröffentlicht in:	Academic radiology 2014-01, Vol.21 (1), p.64-71
Hauptverfasser:	Rossi, Maija Elina, Ruottinen, Hanna, Saunamäki, Tiia, Elovaara, Irina, Dastidar, Prasun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anisotropy Biomarkers - metabolism Brain - metabolism Brain - pathology Caudate Nucleus - metabolism Diffusion Magnetic Resonance Imaging - methods Early Diagnosis Female Follow-Up Studies Globus Pallidus - metabolism Humans Iron - metabolism Male Middle Aged Parkinson Disease - diagnosis Parkinson Disease - metabolism Parkinson Disease - pathology Reproducibility of Results Sensitivity and Specificity Thalamus - metabolism Tissue Distribution
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