Design and Preparation of Single-Chain Nanocarriers Mimicking Disordered Proteins for Combined Delivery of Dermal Bioactive Cargos

Inspired by the multifunctionality of vitamin D‐binding protein and the multiple transient‐binding behavior of some intrinsically disordered proteins (IDPs), a polymeric platform is designed, prepared, and characterized for combined delivery of dermal protective and anticancer bioactive cargos on th...

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Veröffentlicht in:	Macromolecular rapid communications. 2013-11, Vol.34 (21), p.1681-1686
Hauptverfasser:	Sanchez-Sanchez, Ana, Akbari, Somayeh, Moreno, Angel J., Verso, Federica Lo, Arbe, Arantxa, Colmenero, Juan, Pomposo, José A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - administration & dosage Applied sciences Biological and medical sciences Cancer Cell Line, Tumor Chemical reactions and properties Crosslinking, vulcanization Drug Carriers - chemical synthesis Drug Carriers - chemistry drug delivery Exact sciences and technology Folic acid Folic Acid - administration & dosage Folic Acid - pharmacology General pharmacology Humans Intrinsically Disordered Proteins - chemical synthesis Intrinsically Disordered Proteins - chemistry Medical sciences Melanoma - drug therapy Melanoma - pathology Molecular Dynamics Simulation Molecular Mimicry Monoterpenes - administration & dosage nanocarriers nanomedicine nanoparticles Nanoparticles - chemistry Organic polymers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers Protective Agents - administration & dosage Protective Agents - pharmacology self-assembly Skin - drug effects Tropolone - administration & dosage Tropolone - analogs & derivatives Vitamin B
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