On-line measurement and control of penicillin V production in a tower loop reactor

Penicillin V was produced in a 98‐dm 3 tower loop reactor using a production strain of Penicillium chrysogenum in pellet form. By using control devices, the aeration, the only energy input in a tower loop reactor, decreased by an average of 75%. The amounts of precursor substance (phenoxyacetic acid...

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Veröffentlicht in:	Journal of chemical technology and biotechnology (1986) 1987, Vol.38 (1), p.41-53
Hauptverfasser:	Lorenz, Th, Diekmann, J., Frueh, K., Hiddessen, R., Moeller, J., Niehoff, J., Schügerl, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Biological and medical sciences bioreactors Biotechnology fermentation Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects on-line control osygen tension control P. chrysogenum Penicillin penicillin V Penicillium chrysogenum Production of active biomolecules tower loop reactor
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