Cytogenetics of human sperm: Meiotic segregation in two translocations carriers

Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8; 15)(p22; q21) and t(3; 16)(p23; q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternated a...

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Veröffentlicht in:American journal of human genetics 1986-01, Vol.38 (2), p.197-208
Hauptverfasser: Brandriff, B, Gordon, L, Ashworth, L K, Littman, V, Watchmaker, G, Carrano, A V
Format: Artikel
Sprache:eng
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Zusammenfassung:Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8; 15)(p22; q21) and t(3; 16)(p23; q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternated and adjacent 1 percentages were similar. The 3:1 segregation frequencies produced by the two translocations were 3.5% and 5.0%.
ISSN:0002-9297