Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia
Antisera were produced against N-acetylaspartylglutamate (NAAG) and were used to localize the molecule within the retina and spinal sensory ganglia of Rana pipiens. NAAG immunoreactivity (IR) in the retina was confined to a subpopulation of amacrine and bipolar cells. The dipeptide was present in th...
Gespeichert in:
| Veröffentlicht in: | Brain research 1987-03, Vol.406 (1), p.397-401 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 401 |
|---|---|
| container_issue | 1 |
| container_start_page | 397 |
| container_title | Brain research |
| container_volume | 406 |
| creator | Kowalski, Michele M. Cassidy, Martha Namboodiri, M.A.A. Neale, Joseph H. |
| description | Antisera were produced against N-acetylaspartylglutamate (NAAG) and were used to localize the molecule within the retina and spinal sensory ganglia of
Rana pipiens. NAAG immunoreactivity (IR) in the retina was confined to a subpopulation of amacrine and bipolar cells. The dipeptide was present in the perikarya of these cells and their neurites which terminated in two discrete bands of the inner plexiform layer. Some NAAG-IR was also present in the outer plexiform layer and the inner segment layer. In spinal ganglia, a subpopulation of relatively large sensory neuron cell bodies expressed NAAG-IR. These data are consistent with the hypothesis that this dipeptide has a function which is specific to discrete subclasses of neurons. In the amphibian retina, the NAAG distribution can be related to the reported involvement of the N-methyl-
d-aspartate receptor in neurotransmission at the level of amacrine and ganglion cells. |
| doi_str_mv | 10.1016/0006-8993(87)90814-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_14704240</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0006899387908146</els_id><sourcerecordid>14704240</sourcerecordid><originalsourceid>FETCH-LOGICAL-c463t-afa01a073f0177734bf57cad959446ad183e33f86153a639dcad2b3ebd7bd6e33</originalsourceid><addsrcrecordid>eNp9kM2OFCEURolxMrajb6AJC2N0USMUNFAbE9PxL5mMG12TW3CrxVBUCVUmPU8vbXd66epCvnO_wCHkBWe3nHH1jjGmGtN14o3RbztmuGzUI7LhRreNaiV7TDYX5Al5WsqvehWiY9fkujWmNS3fENhhjGuETOPkIIYHWMKU6DTQ-wYcLocIZYZc5z6uC4ywIA2Jwjj_DH2ARDMuIQGF5GmZ6ynSgqlM-UD3kPYxwDNyNUAs-Pw8b8iPTx-_7740d98-f919uGucVGJpYADGgWkxMK61FrIfttqB77adlAo8NwKFGIziWwFKdL5mbS-w97r3qkY35PWpd87T7xXLYsdQXP0dJJzWYrnUTFYtFZQn0OWplIyDnXMYIR8sZ_Zo1h612aM2a7T9Z9aquvby3L_2I_rL0lllzV-dcyjV5JAhuVAuWC1plTIVe3_CsLr4EzDb4gImhz5kdIv1U_j_O_4CT9aWSA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14704240</pqid></control><display><type>article</type><title>Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Kowalski, Michele M. ; Cassidy, Martha ; Namboodiri, M.A.A. ; Neale, Joseph H.</creator><creatorcontrib>Kowalski, Michele M. ; Cassidy, Martha ; Namboodiri, M.A.A. ; Neale, Joseph H.</creatorcontrib><description>Antisera were produced against N-acetylaspartylglutamate (NAAG) and were used to localize the molecule within the retina and spinal sensory ganglia of
Rana pipiens. NAAG immunoreactivity (IR) in the retina was confined to a subpopulation of amacrine and bipolar cells. The dipeptide was present in the perikarya of these cells and their neurites which terminated in two discrete bands of the inner plexiform layer. Some NAAG-IR was also present in the outer plexiform layer and the inner segment layer. In spinal ganglia, a subpopulation of relatively large sensory neuron cell bodies expressed NAAG-IR. These data are consistent with the hypothesis that this dipeptide has a function which is specific to discrete subclasses of neurons. In the amphibian retina, the NAAG distribution can be related to the reported involvement of the N-methyl-
d-aspartate receptor in neurotransmission at the level of amacrine and ganglion cells.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(87)90814-6</identifier><identifier>PMID: 2882821</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Amphibian ; Animals ; Biological and medical sciences ; Central nervous system ; Central neurotransmission. Neuromudulation. Pathways and receptors ; Dipeptides - metabolism ; Fluorescent Antibody Technique ; Fundamental and applied biological sciences. Psychology ; Ganglia, Spinal - metabolism ; Immunohistochemistry ; N-Acetylaspartylglutamate ; Neuropeptide ; Neurotransmitter Agents - metabolism ; Rana pipiens ; Ranidae ; Retina ; Retina - metabolism ; Retinal Ganglion Cells - metabolism ; Spinal sensory neuron ; Superior Colliculi - metabolism ; Synaptic Transmission ; Vertebrates: nervous system and sense organs</subject><ispartof>Brain research, 1987-03, Vol.406 (1), p.397-401</ispartof><rights>1987 Elsevier Science Publishers B.V. (Biomedical Division)</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c463t-afa01a073f0177734bf57cad959446ad183e33f86153a639dcad2b3ebd7bd6e33</citedby><cites>FETCH-LOGICAL-c463t-afa01a073f0177734bf57cad959446ad183e33f86153a639dcad2b3ebd7bd6e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0006-8993(87)90814-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8142668$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2882821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kowalski, Michele M.</creatorcontrib><creatorcontrib>Cassidy, Martha</creatorcontrib><creatorcontrib>Namboodiri, M.A.A.</creatorcontrib><creatorcontrib>Neale, Joseph H.</creatorcontrib><title>Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Antisera were produced against N-acetylaspartylglutamate (NAAG) and were used to localize the molecule within the retina and spinal sensory ganglia of
Rana pipiens. NAAG immunoreactivity (IR) in the retina was confined to a subpopulation of amacrine and bipolar cells. The dipeptide was present in the perikarya of these cells and their neurites which terminated in two discrete bands of the inner plexiform layer. Some NAAG-IR was also present in the outer plexiform layer and the inner segment layer. In spinal ganglia, a subpopulation of relatively large sensory neuron cell bodies expressed NAAG-IR. These data are consistent with the hypothesis that this dipeptide has a function which is specific to discrete subclasses of neurons. In the amphibian retina, the NAAG distribution can be related to the reported involvement of the N-methyl-
d-aspartate receptor in neurotransmission at the level of amacrine and ganglion cells.</description><subject>Amphibian</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Central nervous system</subject><subject>Central neurotransmission. Neuromudulation. Pathways and receptors</subject><subject>Dipeptides - metabolism</subject><subject>Fluorescent Antibody Technique</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Ganglia, Spinal - metabolism</subject><subject>Immunohistochemistry</subject><subject>N-Acetylaspartylglutamate</subject><subject>Neuropeptide</subject><subject>Neurotransmitter Agents - metabolism</subject><subject>Rana pipiens</subject><subject>Ranidae</subject><subject>Retina</subject><subject>Retina - metabolism</subject><subject>Retinal Ganglion Cells - metabolism</subject><subject>Spinal sensory neuron</subject><subject>Superior Colliculi - metabolism</subject><subject>Synaptic Transmission</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM2OFCEURolxMrajb6AJC2N0USMUNFAbE9PxL5mMG12TW3CrxVBUCVUmPU8vbXd66epCvnO_wCHkBWe3nHH1jjGmGtN14o3RbztmuGzUI7LhRreNaiV7TDYX5Al5WsqvehWiY9fkujWmNS3fENhhjGuETOPkIIYHWMKU6DTQ-wYcLocIZYZc5z6uC4ywIA2Jwjj_DH2ARDMuIQGF5GmZ6ynSgqlM-UD3kPYxwDNyNUAs-Pw8b8iPTx-_7740d98-f919uGucVGJpYADGgWkxMK61FrIfttqB77adlAo8NwKFGIziWwFKdL5mbS-w97r3qkY35PWpd87T7xXLYsdQXP0dJJzWYrnUTFYtFZQn0OWplIyDnXMYIR8sZ_Zo1h612aM2a7T9Z9aquvby3L_2I_rL0lllzV-dcyjV5JAhuVAuWC1plTIVe3_CsLr4EzDb4gImhz5kdIv1U_j_O_4CT9aWSA</recordid><startdate>19870317</startdate><enddate>19870317</enddate><creator>Kowalski, Michele M.</creator><creator>Cassidy, Martha</creator><creator>Namboodiri, M.A.A.</creator><creator>Neale, Joseph H.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope></search><sort><creationdate>19870317</creationdate><title>Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia</title><author>Kowalski, Michele M. ; Cassidy, Martha ; Namboodiri, M.A.A. ; Neale, Joseph H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c463t-afa01a073f0177734bf57cad959446ad183e33f86153a639dcad2b3ebd7bd6e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Amphibian</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Central nervous system</topic><topic>Central neurotransmission. Neuromudulation. Pathways and receptors</topic><topic>Dipeptides - metabolism</topic><topic>Fluorescent Antibody Technique</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Ganglia, Spinal - metabolism</topic><topic>Immunohistochemistry</topic><topic>N-Acetylaspartylglutamate</topic><topic>Neuropeptide</topic><topic>Neurotransmitter Agents - metabolism</topic><topic>Rana pipiens</topic><topic>Ranidae</topic><topic>Retina</topic><topic>Retina - metabolism</topic><topic>Retinal Ganglion Cells - metabolism</topic><topic>Spinal sensory neuron</topic><topic>Superior Colliculi - metabolism</topic><topic>Synaptic Transmission</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kowalski, Michele M.</creatorcontrib><creatorcontrib>Cassidy, Martha</creatorcontrib><creatorcontrib>Namboodiri, M.A.A.</creatorcontrib><creatorcontrib>Neale, Joseph H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kowalski, Michele M.</au><au>Cassidy, Martha</au><au>Namboodiri, M.A.A.</au><au>Neale, Joseph H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1987-03-17</date><risdate>1987</risdate><volume>406</volume><issue>1</issue><spage>397</spage><epage>401</epage><pages>397-401</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>Antisera were produced against N-acetylaspartylglutamate (NAAG) and were used to localize the molecule within the retina and spinal sensory ganglia of
Rana pipiens. NAAG immunoreactivity (IR) in the retina was confined to a subpopulation of amacrine and bipolar cells. The dipeptide was present in the perikarya of these cells and their neurites which terminated in two discrete bands of the inner plexiform layer. Some NAAG-IR was also present in the outer plexiform layer and the inner segment layer. In spinal ganglia, a subpopulation of relatively large sensory neuron cell bodies expressed NAAG-IR. These data are consistent with the hypothesis that this dipeptide has a function which is specific to discrete subclasses of neurons. In the amphibian retina, the NAAG distribution can be related to the reported involvement of the N-methyl-
d-aspartate receptor in neurotransmission at the level of amacrine and ganglion cells.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>2882821</pmid><doi>10.1016/0006-8993(87)90814-6</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 1987-03, Vol.406 (1), p.397-401 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_14704240 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Amphibian Animals Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Dipeptides - metabolism Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Ganglia, Spinal - metabolism Immunohistochemistry N-Acetylaspartylglutamate Neuropeptide Neurotransmitter Agents - metabolism Rana pipiens Ranidae Retina Retina - metabolism Retinal Ganglion Cells - metabolism Spinal sensory neuron Superior Colliculi - metabolism Synaptic Transmission Vertebrates: nervous system and sense organs |
| title | Cellular localization of N-acetylaspartylglutamate in amphibian retina and spinal sensory ganglia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T02%3A39%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cellular%20localization%20of%20N-acetylaspartylglutamate%20in%20amphibian%20retina%20and%20spinal%20sensory%20ganglia&rft.jtitle=Brain%20research&rft.au=Kowalski,%20Michele%20M.&rft.date=1987-03-17&rft.volume=406&rft.issue=1&rft.spage=397&rft.epage=401&rft.pages=397-401&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/0006-8993(87)90814-6&rft_dat=%3Cproquest_cross%3E14704240%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14704240&rft_id=info:pmid/2882821&rft_els_id=0006899387908146&rfr_iscdi=true |