In Vivo Multimodality Imaging and Cancer Therapy by Near-Infrared Light-Triggered trans-Platinum Pro-Drug-Conjugated Upconverison Nanoparticles

Controlling anticancer drug activity and release on demand is very significant in cancer therapy. The photoactivated platinum(IV) pro-drug is stable in the dark and can be activated by UV light. In this study, we develop a multi­functional drug delivery system combining upconversion luminescence/mag...

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Veröffentlicht in:	Journal of the American Chemical Society 2013-12, Vol.135 (50), p.18920-18929
Hauptverfasser:	Dai, Yunlu, Xiao, Haihua, Liu, Jianhua, Yuan, Qinghai, Ma, Ping’an, Yang, Dongmei, Li, Chunxia, Cheng, Ziyong, Hou, Zhiyao, Yang, Piaoping, Lin, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Magnetic Resonance Imaging Microscopy, Electron, Transmission Multimodal Imaging Nanoparticles Neoplasms - therapy Platinum - administration & dosage Prodrugs - administration & dosage Spectrophotometry, Ultraviolet Tomography, X-Ray Computed
Online-Zugang:	Volltext
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