Adrenal and pituitary incidentalomas in a case of Cushing's syndrome
Cushing's syndrome is a pathological condition where surgery may be lifesaving. The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors an...
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| Veröffentlicht in: | Chirurgia (Bucharest, Romania : 1990) Romania : 1990), 2013-11, Vol.108 (6), p.886-891 |
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| container_title | Chirurgia (Bucharest, Romania : 1990) |
| container_volume | 108 |
| creator | Poiană, C Chiriţă, C Carşote, M Hortopan, D Ioachim, D Corneci, C M Stănescu, B |
| description | Cushing's syndrome is a pathological condition where surgery may be lifesaving. The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and a high dose Dexamethasone test. She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. Two years after the intervention, she still requires adrenal substitution therapy. Acute adrenal crisis is a serious complication of adrenal surgery, with high mortality if unrecognized. |
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The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and a high dose Dexamethasone test. She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. Two years after the intervention, she still requires adrenal substitution therapy. Acute adrenal crisis is a serious complication of adrenal surgery, with high mortality if unrecognized.</description><identifier>ISSN: 1221-9118</identifier><identifier>PMID: 24331331</identifier><language>eng</language><publisher>Romania</publisher><subject>Adenoma - complications ; Adenoma - diagnosis ; Adenoma - surgery ; Adrenal Gland Neoplasms - complications ; Adrenal Gland Neoplasms - diagnosis ; Adrenal Gland Neoplasms - surgery ; Adrenal Insufficiency - drug therapy ; Adrenal Insufficiency - etiology ; Adrenalectomy - adverse effects ; Adult ; Body Mass Index ; Cushing Syndrome - complications ; Cushing Syndrome - diagnosis ; Cushing Syndrome - surgery ; Diabetes Mellitus, Type 2 - complications ; Drug Therapy, Combination ; Female ; Follow-Up Studies ; Glucocorticoids - therapeutic use ; Humans ; Hypertension - complications ; Hypoglycemic Agents - therapeutic use ; Incidental Findings ; Laparoscopy ; Metformin - therapeutic use ; Obesity - complications ; Pituitary Neoplasms - complications ; Pituitary Neoplasms - diagnosis ; Risk Factors ; Treatment Outcome ; Treatment Refusal</subject><ispartof>Chirurgia (Bucharest, Romania : 1990), 2013-11, Vol.108 (6), p.886-891</ispartof><rights>Celsius.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24331331$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Poiană, C</creatorcontrib><creatorcontrib>Chiriţă, C</creatorcontrib><creatorcontrib>Carşote, M</creatorcontrib><creatorcontrib>Hortopan, D</creatorcontrib><creatorcontrib>Ioachim, D</creatorcontrib><creatorcontrib>Corneci, C M</creatorcontrib><creatorcontrib>Stănescu, B</creatorcontrib><title>Adrenal and pituitary incidentalomas in a case of Cushing's syndrome</title><title>Chirurgia (Bucharest, Romania : 1990)</title><addtitle>Chirurgia (Bucur)</addtitle><description>Cushing's syndrome is a pathological condition where surgery may be lifesaving. The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and a high dose Dexamethasone test. She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. Two years after the intervention, she still requires adrenal substitution therapy. Acute adrenal crisis is a serious complication of adrenal surgery, with high mortality if unrecognized.</description><subject>Adenoma - complications</subject><subject>Adenoma - diagnosis</subject><subject>Adenoma - surgery</subject><subject>Adrenal Gland Neoplasms - complications</subject><subject>Adrenal Gland Neoplasms - diagnosis</subject><subject>Adrenal Gland Neoplasms - surgery</subject><subject>Adrenal Insufficiency - drug therapy</subject><subject>Adrenal Insufficiency - etiology</subject><subject>Adrenalectomy - adverse effects</subject><subject>Adult</subject><subject>Body Mass Index</subject><subject>Cushing Syndrome - complications</subject><subject>Cushing Syndrome - diagnosis</subject><subject>Cushing Syndrome - surgery</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>Incidental Findings</subject><subject>Laparoscopy</subject><subject>Metformin - therapeutic use</subject><subject>Obesity - complications</subject><subject>Pituitary Neoplasms - complications</subject><subject>Pituitary Neoplasms - diagnosis</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><subject>Treatment Refusal</subject><issn>1221-9118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j09LxDAUxHNQ3GXdryC56aWQlzRNe1zqv4UFL3our82LRtq0Nu1hv70B12FgGBh-MFdsC1JCVgGUG7aP8VskFUIKoW7YRuZKQfKWPR7sTAF7jsHyyS-rX3A-cx86byks2I8DxlQ58g4j8dHxeo1fPnzeRx7Pwc7jQLfs2mEfaX_JHft4fnqvX7PT28uxPpyySQIsGRgLQkmRC9d1kBetkhIVOitbZQqNwiog0pRXpdHGOQNVobXJQZAVuSW1Yw9_3Gkef1aKSzP42FHfY6BxjU1iVhK0KGWa3l2mazuQbabZD-lY8_9c_QK_9FLp</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>Poiană, C</creator><creator>Chiriţă, C</creator><creator>Carşote, M</creator><creator>Hortopan, D</creator><creator>Ioachim, D</creator><creator>Corneci, C M</creator><creator>Stănescu, B</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20131101</creationdate><title>Adrenal and pituitary incidentalomas in a case of Cushing's syndrome</title><author>Poiană, C ; 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The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and a high dose Dexamethasone test. She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. Two years after the intervention, she still requires adrenal substitution therapy. Acute adrenal crisis is a serious complication of adrenal surgery, with high mortality if unrecognized.</abstract><cop>Romania</cop><pmid>24331331</pmid><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 1221-9118 |
| ispartof | Chirurgia (Bucharest, Romania : 1990), 2013-11, Vol.108 (6), p.886-891 |
| issn | 1221-9118 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adenoma - complications Adenoma - diagnosis Adenoma - surgery Adrenal Gland Neoplasms - complications Adrenal Gland Neoplasms - diagnosis Adrenal Gland Neoplasms - surgery Adrenal Insufficiency - drug therapy Adrenal Insufficiency - etiology Adrenalectomy - adverse effects Adult Body Mass Index Cushing Syndrome - complications Cushing Syndrome - diagnosis Cushing Syndrome - surgery Diabetes Mellitus, Type 2 - complications Drug Therapy, Combination Female Follow-Up Studies Glucocorticoids - therapeutic use Humans Hypertension - complications Hypoglycemic Agents - therapeutic use Incidental Findings Laparoscopy Metformin - therapeutic use Obesity - complications Pituitary Neoplasms - complications Pituitary Neoplasms - diagnosis Risk Factors Treatment Outcome Treatment Refusal |
| title | Adrenal and pituitary incidentalomas in a case of Cushing's syndrome |
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