Experience of using of octreotide-depot in prevention of the development and treatment of external pancreatic fistulas of different genesis
In the period from 2011 till 2012 the Otcreotide-depot was used by the authors in treatment of 34 patients. The patients were divided into two groups: the first group--the prevention of development and the second group--the treatment of external pancreatic fistulas. Ocreotide-depot was applied in 17...
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| Veröffentlicht in: | Vestnik hirurgii im. I.I. Grekova 2013, Vol.172 (3), p.94-96 |
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| container_title | Vestnik hirurgii im. I.I. Grekova |
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| creator | Kabanov, M Iu Solov'ev, I A Iakovleva, D M Sementsov, K V Kradenov, A V |
| description | In the period from 2011 till 2012 the Otcreotide-depot was used by the authors in treatment of 34 patients. The patients were divided into two groups: the first group--the prevention of development and the second group--the treatment of external pancreatic fistulas. Ocreotide-depot was applied in 17 patient of the first group: as part of the complex therapy of severe pancreatitis in 4 patients and after pacreaticoduodenectomy in 13 patients. Ocreotide-depot was used in 17 patients of the second group: 7 cases of patients after different types of pancreatic resections and after external drainage of pancreatic cysts in 10 patients. The positive effect of using the drug was obtained in 30 patients (88.25%): the cases of preventive application of drug in 17 patients and during the treatment of external pancreatic fistulas in 13 patients. The preventive and therapeutic usage of Ocreotide-depot facilitated an uncomplicated postoperative period in 13 cases and the healing of the external pancreatic fistulas in terms from 5 till 7 days in 13 patients. The application of Ocreotide-depot could be recommended as a preventive measure against the incompetence of pancreaticojejunoanastomosis after pancreaticoduodenectomy in complex therapy of severe pancreatitis and also in treatment of external pancreatic fistulas after pancreaticoduodenectomy and percutaneous drainage of postnecrotic pseudocysts. |
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The application of Ocreotide-depot could be recommended as a preventive measure against the incompetence of pancreaticojejunoanastomosis after pancreaticoduodenectomy in complex therapy of severe pancreatitis and also in treatment of external pancreatic fistulas after pancreaticoduodenectomy and percutaneous drainage of postnecrotic pseudocysts.</description><identifier>ISSN: 0042-4625</identifier><identifier>PMID: 24340982</identifier><language>rus</language><publisher>Russia (Federation)</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cutaneous Fistula - etiology ; Cutaneous Fistula - therapy ; Dose-Response Relationship, Drug ; Drainage - methods ; Female ; Follow-Up Studies ; Gastrointestinal Agents - administration & dosage ; Humans ; Injections, Intramuscular ; Male ; Middle Aged ; Octreotide - administration & dosage ; Pancreatic Fistula - etiology ; Pancreatic Fistula - therapy ; Pancreatic Pseudocyst - complications ; Pancreaticoduodenectomy - methods ; Pancreatitis - complications ; Retrospective Studies ; Treatment Outcome</subject><ispartof>Vestnik hirurgii im. 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Grekova</title><addtitle>Vestn Khir Im I I Grek</addtitle><description>In the period from 2011 till 2012 the Otcreotide-depot was used by the authors in treatment of 34 patients. The patients were divided into two groups: the first group--the prevention of development and the second group--the treatment of external pancreatic fistulas. Ocreotide-depot was applied in 17 patient of the first group: as part of the complex therapy of severe pancreatitis in 4 patients and after pacreaticoduodenectomy in 13 patients. Ocreotide-depot was used in 17 patients of the second group: 7 cases of patients after different types of pancreatic resections and after external drainage of pancreatic cysts in 10 patients. The positive effect of using the drug was obtained in 30 patients (88.25%): the cases of preventive application of drug in 17 patients and during the treatment of external pancreatic fistulas in 13 patients. The preventive and therapeutic usage of Ocreotide-depot facilitated an uncomplicated postoperative period in 13 cases and the healing of the external pancreatic fistulas in terms from 5 till 7 days in 13 patients. The application of Ocreotide-depot could be recommended as a preventive measure against the incompetence of pancreaticojejunoanastomosis after pancreaticoduodenectomy in complex therapy of severe pancreatitis and also in treatment of external pancreatic fistulas after pancreaticoduodenectomy and percutaneous drainage of postnecrotic pseudocysts.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cutaneous Fistula - etiology</subject><subject>Cutaneous Fistula - therapy</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drainage - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastrointestinal Agents - administration & dosage</subject><subject>Humans</subject><subject>Injections, Intramuscular</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Octreotide - administration & dosage</subject><subject>Pancreatic Fistula - etiology</subject><subject>Pancreatic Fistula - therapy</subject><subject>Pancreatic Pseudocyst - complications</subject><subject>Pancreaticoduodenectomy - methods</subject><subject>Pancreatitis - complications</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>0042-4625</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMtOwzAQRbMA0ar0F5CXbCL5lYeXqCoPqRIbWEeOPS5GiW1sB5Vv4KdJoKxm7r1n7mIuijXGnJa8ptWq2Kb0jjGmdUMZ5lfFinLGsWjpuvjenwJEC04B8gZNybrjsniVI_hsNZQags_IOhQifILL1ruFyG-A9GwMPoyzi6TTaL6R-VfNAJwyRCcHFKRTS2AVMjblaZBpybU1BuICH8FBsum6uDRySLA9z03xer9_2T2Wh-eHp93doQyE1rnUhAhoRNvXTa9IzRrSECykAgGEzLqvuDGGCkywZrqtKO9136uqxVRUvCVsU9z-9YboPyZIuRttUjAM0oGfUkd4LSjhrKYzenNGp34E3YVoRxm_uv8Hsh9buW6g</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Kabanov, M Iu</creator><creator>Solov'ev, I A</creator><creator>Iakovleva, D M</creator><creator>Sementsov, K V</creator><creator>Kradenov, A V</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2013</creationdate><title>Experience of using of octreotide-depot in prevention of the development and treatment of external pancreatic fistulas of different genesis</title><author>Kabanov, M Iu ; Solov'ev, I A ; Iakovleva, D M ; Sementsov, K V ; Kradenov, A V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-d119e798b67bc163717109ace9e11163b54fff29010d3d8524bdbbc5802954813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>rus</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cutaneous Fistula - etiology</topic><topic>Cutaneous Fistula - therapy</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drainage - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastrointestinal Agents - administration & dosage</topic><topic>Humans</topic><topic>Injections, Intramuscular</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Octreotide - administration & dosage</topic><topic>Pancreatic Fistula - etiology</topic><topic>Pancreatic Fistula - therapy</topic><topic>Pancreatic Pseudocyst - complications</topic><topic>Pancreaticoduodenectomy - methods</topic><topic>Pancreatitis - complications</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kabanov, M Iu</creatorcontrib><creatorcontrib>Solov'ev, I A</creatorcontrib><creatorcontrib>Iakovleva, D M</creatorcontrib><creatorcontrib>Sementsov, K V</creatorcontrib><creatorcontrib>Kradenov, A V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Vestnik hirurgii im. 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Ocreotide-depot was applied in 17 patient of the first group: as part of the complex therapy of severe pancreatitis in 4 patients and after pacreaticoduodenectomy in 13 patients. Ocreotide-depot was used in 17 patients of the second group: 7 cases of patients after different types of pancreatic resections and after external drainage of pancreatic cysts in 10 patients. The positive effect of using the drug was obtained in 30 patients (88.25%): the cases of preventive application of drug in 17 patients and during the treatment of external pancreatic fistulas in 13 patients. The preventive and therapeutic usage of Ocreotide-depot facilitated an uncomplicated postoperative period in 13 cases and the healing of the external pancreatic fistulas in terms from 5 till 7 days in 13 patients. The application of Ocreotide-depot could be recommended as a preventive measure against the incompetence of pancreaticojejunoanastomosis after pancreaticoduodenectomy in complex therapy of severe pancreatitis and also in treatment of external pancreatic fistulas after pancreaticoduodenectomy and percutaneous drainage of postnecrotic pseudocysts.</abstract><cop>Russia (Federation)</cop><pmid>24340982</pmid><tpages>3</tpages></addata></record> |
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| ispartof | Vestnik hirurgii im. I.I. Grekova, 2013, Vol.172 (3), p.94-96 |
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| language | rus |
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| source | MEDLINE; DOAJ Directory of Open Access Journals |
| subjects | Adult Aged Aged, 80 and over Cutaneous Fistula - etiology Cutaneous Fistula - therapy Dose-Response Relationship, Drug Drainage - methods Female Follow-Up Studies Gastrointestinal Agents - administration & dosage Humans Injections, Intramuscular Male Middle Aged Octreotide - administration & dosage Pancreatic Fistula - etiology Pancreatic Fistula - therapy Pancreatic Pseudocyst - complications Pancreaticoduodenectomy - methods Pancreatitis - complications Retrospective Studies Treatment Outcome |
| title | Experience of using of octreotide-depot in prevention of the development and treatment of external pancreatic fistulas of different genesis |
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