Alvarado score: a guide to computed tomography utilization in appendicitis

Background Although useful in evaluation of suspected appendicitis, not all patients require computed tomography (CT) evaluation. Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into...

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Veröffentlicht in:ANZ journal of surgery 2013-10, Vol.83 (10), p.748-752
Hauptverfasser: Tan, Winson Jianhong, Pek, Wansze, Kabir, Tousif, Goh, Yaw Chong, Chan, Weng Hoong, Wong, Wai Keong, Ong, Hock Soo
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container_end_page 752
container_issue 10
container_start_page 748
container_title ANZ journal of surgery
container_volume 83
creator Tan, Winson Jianhong
Pek, Wansze
Kabir, Tousif
Goh, Yaw Chong
Chan, Weng Hoong
Wong, Wai Keong
Ong, Hock Soo
description Background Although useful in evaluation of suspected appendicitis, not all patients require computed tomography (CT) evaluation. Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into subgroups who benefit from CT evaluation and propose an objective algorithm with AS guiding CT utilization. Methods This study is a retrospective review of medical records of all patients admitted for suspected appendicitis over a 6‐month duration. Relevant data were recorded. The AS for each patient was determined retrospectively and correlated with histological and CT findings. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were determined for various ASs and for CT. Results Three hundred fifty‐eight patients were studied, with 167 males (46.6%) and 191 females (53.4%). Prevalence of appendicitis was 50% (179 patients). Two hundred fourteen patients (59.8%) had CT performed. Surgery was performed for 206 patients (57.5%). Overall negative appendicectomy rate was 13.1%. Patients who underwent CT evaluation had a negative appendicectomy rate of 5.7% compared to 17.9% in those without CT evaluation (P = 0.009). CT scan had a sensitivity and specificity of 92.6% and 96.9%, respectively. An AS greater than 3 had a sensitivity superior to CT (95.5%), while an AS of 9 or greater had a specificity superior to CT (100%). Conclusions In suspected appendicitis, patients who benefit from CT evaluation are those with the AS ranging from 4 to 8. We propose a management algorithm with the AS guiding the necessity for CT evaluation.
doi_str_mv 10.1111/ans.12076
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Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into subgroups who benefit from CT evaluation and propose an objective algorithm with AS guiding CT utilization. Methods This study is a retrospective review of medical records of all patients admitted for suspected appendicitis over a 6‐month duration. Relevant data were recorded. The AS for each patient was determined retrospectively and correlated with histological and CT findings. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were determined for various ASs and for CT. Results Three hundred fifty‐eight patients were studied, with 167 males (46.6%) and 191 females (53.4%). Prevalence of appendicitis was 50% (179 patients). Two hundred fourteen patients (59.8%) had CT performed. Surgery was performed for 206 patients (57.5%). Overall negative appendicectomy rate was 13.1%. Patients who underwent CT evaluation had a negative appendicectomy rate of 5.7% compared to 17.9% in those without CT evaluation (P = 0.009). CT scan had a sensitivity and specificity of 92.6% and 96.9%, respectively. An AS greater than 3 had a sensitivity superior to CT (95.5%), while an AS of 9 or greater had a specificity superior to CT (100%). Conclusions In suspected appendicitis, patients who benefit from CT evaluation are those with the AS ranging from 4 to 8. We propose a management algorithm with the AS guiding the necessity for CT evaluation.</description><identifier>ISSN: 1445-1433</identifier><identifier>EISSN: 1445-2197</identifier><identifier>DOI: 10.1111/ans.12076</identifier><identifier>PMID: 23351046</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Acute Disease ; Adult ; Algorithms ; Appendectomy - statistics &amp; numerical data ; Appendicitis ; Appendicitis - diagnostic imaging ; Appendicitis - surgery ; Computers ; Decision Support Techniques ; Diagnosis, Differential ; False Positive Reactions ; Female ; general surgery ; Humans ; Male ; Predictive Value of Tests ; Retrospective Studies ; Sensitivity and Specificity ; Tomography ; Tomography, X-Ray Computed ; Unnecessary Procedures - statistics &amp; numerical data</subject><ispartof>ANZ journal of surgery, 2013-10, Vol.83 (10), p.748-752</ispartof><rights>2013 The Authors. ANZ Journal of Surgery © 2013 Royal Australasian College of Surgeons</rights><rights>2013 The Authors. ANZ Journal of Surgery © 2013 Royal Australasian College of Surgeons.</rights><rights>ANZ Journal of Surgery © 2013 Royal Australasian College of Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fans.12076$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fans.12076$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23351046$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tan, Winson Jianhong</creatorcontrib><creatorcontrib>Pek, Wansze</creatorcontrib><creatorcontrib>Kabir, Tousif</creatorcontrib><creatorcontrib>Goh, Yaw Chong</creatorcontrib><creatorcontrib>Chan, Weng Hoong</creatorcontrib><creatorcontrib>Wong, Wai Keong</creatorcontrib><creatorcontrib>Ong, Hock Soo</creatorcontrib><title>Alvarado score: a guide to computed tomography utilization in appendicitis</title><title>ANZ journal of surgery</title><addtitle>ANZ J Surg</addtitle><description>Background Although useful in evaluation of suspected appendicitis, not all patients require computed tomography (CT) evaluation. Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into subgroups who benefit from CT evaluation and propose an objective algorithm with AS guiding CT utilization. Methods This study is a retrospective review of medical records of all patients admitted for suspected appendicitis over a 6‐month duration. Relevant data were recorded. The AS for each patient was determined retrospectively and correlated with histological and CT findings. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were determined for various ASs and for CT. Results Three hundred fifty‐eight patients were studied, with 167 males (46.6%) and 191 females (53.4%). Prevalence of appendicitis was 50% (179 patients). Two hundred fourteen patients (59.8%) had CT performed. Surgery was performed for 206 patients (57.5%). Overall negative appendicectomy rate was 13.1%. Patients who underwent CT evaluation had a negative appendicectomy rate of 5.7% compared to 17.9% in those without CT evaluation (P = 0.009). CT scan had a sensitivity and specificity of 92.6% and 96.9%, respectively. An AS greater than 3 had a sensitivity superior to CT (95.5%), while an AS of 9 or greater had a specificity superior to CT (100%). Conclusions In suspected appendicitis, patients who benefit from CT evaluation are those with the AS ranging from 4 to 8. We propose a management algorithm with the AS guiding the necessity for CT evaluation.</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Algorithms</subject><subject>Appendectomy - statistics &amp; numerical data</subject><subject>Appendicitis</subject><subject>Appendicitis - diagnostic imaging</subject><subject>Appendicitis - surgery</subject><subject>Computers</subject><subject>Decision Support Techniques</subject><subject>Diagnosis, Differential</subject><subject>False Positive Reactions</subject><subject>Female</subject><subject>general surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Predictive Value of Tests</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><subject>Unnecessary Procedures - statistics &amp; numerical data</subject><issn>1445-1433</issn><issn>1445-2197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1Lw0AQhhdRrFYP_gEJePGSdr-38dYWbZVSBSuCl2WTbOrWJBuziVp_vemHPXhyLvPCPO_AzAvAGYId1FRX5a6DMBR8DxwhSpmPUSD2txpRQlrg2LkFhIjzgB2CFiaEIUj5Ebjrpx-qVLH1XGRLfeUpb16bWHuV9SKbFXWl40Zndl6q4nXp1ZVJzbeqjM09k3uqKHQem8hUxp2Ag0SlTp9uexs83VzPhmN_cj-6HfYnviEMcp-HUS9ASSKCRIVKo0jBBApMCSYsjlWgGMVRKCiHgW7mYcg105TxsEdxqBkibXC52VuU9r3WrpKZcZFOU5VrWzuJKO8RQQP0H5QSCkWAew168Qdd2LrMm0NWFIR4u_B8S9VhpmNZlCZT5VL-PrQBuhvg06R6uZsjKFdJySYpuU5K9qePa9E4_I3DuEp_7RyqfJNcEMHk83Qkx7OX6eBhACUlPyCYk7g</recordid><startdate>201310</startdate><enddate>201310</enddate><creator>Tan, Winson Jianhong</creator><creator>Pek, Wansze</creator><creator>Kabir, Tousif</creator><creator>Goh, Yaw Chong</creator><creator>Chan, Weng Hoong</creator><creator>Wong, Wai Keong</creator><creator>Ong, Hock Soo</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>201310</creationdate><title>Alvarado score: a guide to computed tomography utilization in appendicitis</title><author>Tan, Winson Jianhong ; Pek, Wansze ; Kabir, Tousif ; Goh, Yaw Chong ; Chan, Weng Hoong ; Wong, Wai Keong ; Ong, Hock Soo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i3506-6bc891ff79fabae1ca0f07243235dda9a542cb74609ebaebb6e5e456b842be513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acute Disease</topic><topic>Adult</topic><topic>Algorithms</topic><topic>Appendectomy - statistics &amp; numerical data</topic><topic>Appendicitis</topic><topic>Appendicitis - diagnostic imaging</topic><topic>Appendicitis - surgery</topic><topic>Computers</topic><topic>Decision Support Techniques</topic><topic>Diagnosis, Differential</topic><topic>False Positive Reactions</topic><topic>Female</topic><topic>general surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Predictive Value of Tests</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed</topic><topic>Unnecessary Procedures - statistics &amp; numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tan, Winson Jianhong</creatorcontrib><creatorcontrib>Pek, Wansze</creatorcontrib><creatorcontrib>Kabir, Tousif</creatorcontrib><creatorcontrib>Goh, Yaw Chong</creatorcontrib><creatorcontrib>Chan, Weng Hoong</creatorcontrib><creatorcontrib>Wong, Wai Keong</creatorcontrib><creatorcontrib>Ong, Hock Soo</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>ANZ journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tan, Winson Jianhong</au><au>Pek, Wansze</au><au>Kabir, Tousif</au><au>Goh, Yaw Chong</au><au>Chan, Weng Hoong</au><au>Wong, Wai Keong</au><au>Ong, Hock Soo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alvarado score: a guide to computed tomography utilization in appendicitis</atitle><jtitle>ANZ journal of surgery</jtitle><addtitle>ANZ J Surg</addtitle><date>2013-10</date><risdate>2013</risdate><volume>83</volume><issue>10</issue><spage>748</spage><epage>752</epage><pages>748-752</pages><issn>1445-1433</issn><eissn>1445-2197</eissn><abstract>Background Although useful in evaluation of suspected appendicitis, not all patients require computed tomography (CT) evaluation. Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into subgroups who benefit from CT evaluation and propose an objective algorithm with AS guiding CT utilization. Methods This study is a retrospective review of medical records of all patients admitted for suspected appendicitis over a 6‐month duration. Relevant data were recorded. The AS for each patient was determined retrospectively and correlated with histological and CT findings. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were determined for various ASs and for CT. Results Three hundred fifty‐eight patients were studied, with 167 males (46.6%) and 191 females (53.4%). Prevalence of appendicitis was 50% (179 patients). Two hundred fourteen patients (59.8%) had CT performed. Surgery was performed for 206 patients (57.5%). Overall negative appendicectomy rate was 13.1%. Patients who underwent CT evaluation had a negative appendicectomy rate of 5.7% compared to 17.9% in those without CT evaluation (P = 0.009). CT scan had a sensitivity and specificity of 92.6% and 96.9%, respectively. An AS greater than 3 had a sensitivity superior to CT (95.5%), while an AS of 9 or greater had a specificity superior to CT (100%). Conclusions In suspected appendicitis, patients who benefit from CT evaluation are those with the AS ranging from 4 to 8. We propose a management algorithm with the AS guiding the necessity for CT evaluation.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>23351046</pmid><doi>10.1111/ans.12076</doi><tpages>5</tpages></addata></record>
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subjects Acute Disease
Adult
Algorithms
Appendectomy - statistics & numerical data
Appendicitis
Appendicitis - diagnostic imaging
Appendicitis - surgery
Computers
Decision Support Techniques
Diagnosis, Differential
False Positive Reactions
Female
general surgery
Humans
Male
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Tomography
Tomography, X-Ray Computed
Unnecessary Procedures - statistics & numerical data
title Alvarado score: a guide to computed tomography utilization in appendicitis
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