Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics

Objective The downregulation of human leukocyte antigen class I (HLA-I) has been proposed to contribute to the immune evasion of cancer cells in some cancers. Meanwhile, transcriptional silencing by means of promoter methylation is now believed to be an important mechanism of carcinogenesis. The aim...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2011-03, Vol.141 (3), p.808-814
Hauptverfasser:	Qifeng, Sun, MD, Bo, Cong, MD, Xingtao, Jiang, MD, Chuanliang, Peng, MD, Xiaogang, Zhao, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigen processing ATP-Binding Cassette Sub-Family B Member 2 ATP-Binding Cassette Transporters - analysis Biological and medical sciences Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Cardiology. Vascular system Cardiothoracic Surgery Chi-Square Distribution China CpG Islands Cysteine Endopeptidases - analysis DNA Methylation Down-Regulation Esophageal Neoplasms - genetics Esophageal Neoplasms - immunology Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophagus Female Gastroenterology. Liver. Pancreas. Abdomen Genotype Histocompatibility Antigens Class I - analysis Histocompatibility Antigens Class I - genetics Humans Immunohistochemistry Lymphatic Metastasis Major Histocompatibility Complex Male Medical sciences Middle Aged Neoplasm Staging Phenotype Pneumology Polymerase Chain Reaction Prognosis Promoter Regions, Genetic Proportional Hazards Models Survival Analysis Time Factors Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!