The recent multi-ethnic global lung initiative 2012 (GLI2012 ) reference values don't reflect contemporary adult's North African spirometry

Summary Background The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. Objective To ascertain how well the recent ERS/GLI reference equations fit con...

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Veröffentlicht in:Respiratory medicine 2013-12, Vol.107 (12), p.2000-2008
Hauptverfasser: Ben Saad, Helmi, El Attar, Mohamed Nour, Hadj Mabrouk, Khaoula, Abdelaziz, Ahmed Ben, Abdelghani, Ahmed, Bousarssar, Mohamed, Limam, Khélifa, Maatoug, Chiraz, Bouslah, Hmida, Charrada, Ameur, Rouatbi, Sonia
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container_end_page 2008
container_issue 12
container_start_page 2000
container_title Respiratory medicine
container_volume 107
creator Ben Saad, Helmi
El Attar, Mohamed Nour
Hadj Mabrouk, Khaoula
Abdelaziz, Ahmed Ben
Abdelghani, Ahmed
Bousarssar, Mohamed
Limam, Khélifa
Maatoug, Chiraz
Bouslah, Hmida
Charrada, Ameur
Rouatbi, Sonia
description Summary Background The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. Objective To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. Population and methods Spirometric data were recorded from 1192 consecutive spirometry procedures in adults aged 18–60 years. Reference values and lower limits of normality (LLN) were calculated using the local and the ERS/GLI reference equations. Applied definitions : large airway obstructive ventilatory defect ( LAOVD ): FEV1 /FVC 
doi_str_mv 10.1016/j.rmed.2013.10.015
format Article
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Objective To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. Population and methods Spirometric data were recorded from 1192 consecutive spirometry procedures in adults aged 18–60 years. Reference values and lower limits of normality (LLN) were calculated using the local and the ERS/GLI reference equations. Applied definitions : large airway obstructive ventilatory defect ( LAOVD ): FEV1 /FVC &lt; LLN. Tendency to a restrictive ventilatory defect ( TRVD ): FEV1 and FVC &lt; LLN and FEV1 /FVC ≥ LLN. The spirometric profile, according to the two reference equations, was determined. Z-scores for spirometry from North African healthy subjects ( n  = 489) were calculated. If the average Z-score deviated by &lt;±0.5 from the overall mean, the ERS/GLI reference equations would be considered as reflective of contemporary Tunisian spirometry. Results Using Tunisian reference equations, 71.31%, 6.71% and 19.04% of spirometry records were interpreted as normal, and as having, LAOVD and TRVD, respectively. Using the ERS/GLI reference equations, these figures were respectively, 85.82%, 4.19% and 8.39%. The mean ± SD Z-scores for the contemporary healthy North African subject's data were −0.55 ± 0.87 for FEV1 , −0.62 ± 0.86 for FVC and 0.10 ± 0.73 for FEV1 /FVC. Conclusion The present study don't recommend the use of the recent ERS/GLI reference equations to interpret spirometry in North African adult population.</description><identifier>ISSN: 0954-6111</identifier><identifier>EISSN: 1532-3064</identifier><identifier>DOI: 10.1016/j.rmed.2013.10.015</identifier><identifier>PMID: 24231283</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Age ; Age Distribution ; Agreements ; Algeria - ethnology ; Body mass index ; Caucasian race ; Confidence intervals ; Cross-Sectional Studies ; Defects ; Ethnic groups ; European Continental Ancestry Group - ethnology ; Female ; Forced Expiratory Volume - physiology ; Humans ; Lung - physiology ; Male ; Middle Aged ; North Africa ; Nutrition research ; Pulmonary/Respiratory ; Reference Values ; Respiratory system ; Sex Distribution ; Spirometry ; Spirometry - standards ; Studies ; Task forces ; Tunisia - ethnology ; Values ; Vital Capacity - physiology ; Workers ; Young Adult</subject><ispartof>Respiratory medicine, 2013-12, Vol.107 (12), p.2000-2008</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Dec 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-f2871143cb5a14fa04be4abdfa8d46899854004d9fa2bea5173ac950c90247d93</citedby><cites>FETCH-LOGICAL-c483t-f2871143cb5a14fa04be4abdfa8d46899854004d9fa2bea5173ac950c90247d93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0954611113004307$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24231283$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ben Saad, Helmi</creatorcontrib><creatorcontrib>El Attar, Mohamed Nour</creatorcontrib><creatorcontrib>Hadj Mabrouk, Khaoula</creatorcontrib><creatorcontrib>Abdelaziz, Ahmed Ben</creatorcontrib><creatorcontrib>Abdelghani, Ahmed</creatorcontrib><creatorcontrib>Bousarssar, Mohamed</creatorcontrib><creatorcontrib>Limam, Khélifa</creatorcontrib><creatorcontrib>Maatoug, Chiraz</creatorcontrib><creatorcontrib>Bouslah, Hmida</creatorcontrib><creatorcontrib>Charrada, Ameur</creatorcontrib><creatorcontrib>Rouatbi, Sonia</creatorcontrib><title>The recent multi-ethnic global lung initiative 2012 (GLI2012 ) reference values don't reflect contemporary adult's North African spirometry</title><title>Respiratory medicine</title><addtitle>Respir Med</addtitle><description>Summary Background The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. Objective To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. Population and methods Spirometric data were recorded from 1192 consecutive spirometry procedures in adults aged 18–60 years. Reference values and lower limits of normality (LLN) were calculated using the local and the ERS/GLI reference equations. Applied definitions : large airway obstructive ventilatory defect ( LAOVD ): FEV1 /FVC &lt; LLN. Tendency to a restrictive ventilatory defect ( TRVD ): FEV1 and FVC &lt; LLN and FEV1 /FVC ≥ LLN. The spirometric profile, according to the two reference equations, was determined. Z-scores for spirometry from North African healthy subjects ( n  = 489) were calculated. If the average Z-score deviated by &lt;±0.5 from the overall mean, the ERS/GLI reference equations would be considered as reflective of contemporary Tunisian spirometry. Results Using Tunisian reference equations, 71.31%, 6.71% and 19.04% of spirometry records were interpreted as normal, and as having, LAOVD and TRVD, respectively. Using the ERS/GLI reference equations, these figures were respectively, 85.82%, 4.19% and 8.39%. The mean ± SD Z-scores for the contemporary healthy North African subject's data were −0.55 ± 0.87 for FEV1 , −0.62 ± 0.86 for FVC and 0.10 ± 0.73 for FEV1 /FVC. 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El Attar, Mohamed Nour ; Hadj Mabrouk, Khaoula ; Abdelaziz, Ahmed Ben ; Abdelghani, Ahmed ; Bousarssar, Mohamed ; Limam, Khélifa ; Maatoug, Chiraz ; Bouslah, Hmida ; Charrada, Ameur ; Rouatbi, Sonia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-f2871143cb5a14fa04be4abdfa8d46899854004d9fa2bea5173ac950c90247d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Age Distribution</topic><topic>Agreements</topic><topic>Algeria - ethnology</topic><topic>Body mass index</topic><topic>Caucasian race</topic><topic>Confidence intervals</topic><topic>Cross-Sectional Studies</topic><topic>Defects</topic><topic>Ethnic groups</topic><topic>European Continental Ancestry Group - ethnology</topic><topic>Female</topic><topic>Forced Expiratory Volume - physiology</topic><topic>Humans</topic><topic>Lung - physiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>North Africa</topic><topic>Nutrition research</topic><topic>Pulmonary/Respiratory</topic><topic>Reference Values</topic><topic>Respiratory system</topic><topic>Sex Distribution</topic><topic>Spirometry</topic><topic>Spirometry - standards</topic><topic>Studies</topic><topic>Task forces</topic><topic>Tunisia - ethnology</topic><topic>Values</topic><topic>Vital Capacity - physiology</topic><topic>Workers</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ben Saad, Helmi</creatorcontrib><creatorcontrib>El Attar, Mohamed Nour</creatorcontrib><creatorcontrib>Hadj Mabrouk, Khaoula</creatorcontrib><creatorcontrib>Abdelaziz, Ahmed Ben</creatorcontrib><creatorcontrib>Abdelghani, Ahmed</creatorcontrib><creatorcontrib>Bousarssar, Mohamed</creatorcontrib><creatorcontrib>Limam, Khélifa</creatorcontrib><creatorcontrib>Maatoug, Chiraz</creatorcontrib><creatorcontrib>Bouslah, Hmida</creatorcontrib><creatorcontrib>Charrada, Ameur</creatorcontrib><creatorcontrib>Rouatbi, Sonia</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Respiratory medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ben Saad, Helmi</au><au>El Attar, Mohamed Nour</au><au>Hadj Mabrouk, Khaoula</au><au>Abdelaziz, Ahmed Ben</au><au>Abdelghani, Ahmed</au><au>Bousarssar, Mohamed</au><au>Limam, Khélifa</au><au>Maatoug, Chiraz</au><au>Bouslah, Hmida</au><au>Charrada, Ameur</au><au>Rouatbi, Sonia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The recent multi-ethnic global lung initiative 2012 (GLI2012 ) reference values don't reflect contemporary adult's North African spirometry</atitle><jtitle>Respiratory medicine</jtitle><addtitle>Respir Med</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>107</volume><issue>12</issue><spage>2000</spage><epage>2008</epage><pages>2000-2008</pages><issn>0954-6111</issn><eissn>1532-3064</eissn><abstract>Summary Background The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. Objective To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. Population and methods Spirometric data were recorded from 1192 consecutive spirometry procedures in adults aged 18–60 years. Reference values and lower limits of normality (LLN) were calculated using the local and the ERS/GLI reference equations. Applied definitions : large airway obstructive ventilatory defect ( LAOVD ): FEV1 /FVC &lt; LLN. Tendency to a restrictive ventilatory defect ( TRVD ): FEV1 and FVC &lt; LLN and FEV1 /FVC ≥ LLN. The spirometric profile, according to the two reference equations, was determined. Z-scores for spirometry from North African healthy subjects ( n  = 489) were calculated. If the average Z-score deviated by &lt;±0.5 from the overall mean, the ERS/GLI reference equations would be considered as reflective of contemporary Tunisian spirometry. Results Using Tunisian reference equations, 71.31%, 6.71% and 19.04% of spirometry records were interpreted as normal, and as having, LAOVD and TRVD, respectively. Using the ERS/GLI reference equations, these figures were respectively, 85.82%, 4.19% and 8.39%. The mean ± SD Z-scores for the contemporary healthy North African subject's data were −0.55 ± 0.87 for FEV1 , −0.62 ± 0.86 for FVC and 0.10 ± 0.73 for FEV1 /FVC. Conclusion The present study don't recommend the use of the recent ERS/GLI reference equations to interpret spirometry in North African adult population.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>24231283</pmid><doi>10.1016/j.rmed.2013.10.015</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Adolescent
Adult
Age
Age Distribution
Agreements
Algeria - ethnology
Body mass index
Caucasian race
Confidence intervals
Cross-Sectional Studies
Defects
Ethnic groups
European Continental Ancestry Group - ethnology
Female
Forced Expiratory Volume - physiology
Humans
Lung - physiology
Male
Middle Aged
North Africa
Nutrition research
Pulmonary/Respiratory
Reference Values
Respiratory system
Sex Distribution
Spirometry
Spirometry - standards
Studies
Task forces
Tunisia - ethnology
Values
Vital Capacity - physiology
Workers
Young Adult
title The recent multi-ethnic global lung initiative 2012 (GLI2012 ) reference values don't reflect contemporary adult's North African spirometry
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