Working Disability in Norwegian Patients with Vestibular Schwannoma: Vertigo Predicts Future Dependence

Objective We examined whether reduced hearing, tinnitus, dizziness, and unsteadiness affected the patients' ability to maintain work within a time frame of 2–10 years after diagnosis. Methods A total of 434 consecutive patients were followed at regular intervals. Data on symptoms were scored pr...

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Veröffentlicht in:World neurosurgery 2013-12, Vol.80 (6), p.e301-e305
Hauptverfasser: Breivik, Cathrine Nansdal, Nilsen, Roy Miodini, Myrseth, Erling, Finnkirk, Monica Katrine, Lund-Johansen, Morten
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container_end_page e305
container_issue 6
container_start_page e301
container_title World neurosurgery
container_volume 80
creator Breivik, Cathrine Nansdal
Nilsen, Roy Miodini
Myrseth, Erling
Finnkirk, Monica Katrine
Lund-Johansen, Morten
description Objective We examined whether reduced hearing, tinnitus, dizziness, and unsteadiness affected the patients' ability to maintain work within a time frame of 2–10 years after diagnosis. Methods A total of 434 consecutive patients were followed at regular intervals. Data on symptoms were scored prospectively and dichotomized by visual analog scales for tinnitus and vertigo. Study design is retrospective. Hearing acuity was scored according to the Gardner-Robertson scale, and unsteadiness was measured on a balance platform. Patients were asked about working status, and scored as receiving governmental compensation for disability. Results Two hundred six patients were eligible for study. Of these, one died and nine were lost to follow-up. Ninety-seven patients received conservative management, 49 patients recieved gamma knife radiosurgery, and 50 patients were treated by microsurgery. Mean follow-up time was 58.7 months (range, 20–132 months). There was a significant increase in the number of individuals receiving compensation during the study period ( P < 0.0001). At baseline, the proportion of pension receivers was within same range as that of the age- and sex-matched Norwegian population (5.61% vs. 6.91%; case-control odds ratio, 0.82; 95% confidence interval 0.45–1.49; P  = 0.51, not significant). At the final time point, the increase in the number of receivers deviated significantly from the reference population (case-control odds ratio, 3.80; 95% confidence interval 2.71–5.33; P ≤ 0.001). Examining symptoms at first presentation as predictors of future dependence revealed that vertigo and higher mean age were associated with a higher risk ( P < 0.001 and P  = 0.015, respectively). No other symptoms were predictive of dependence. Conclusions In a prospectively followed cohort of Norwegian patients with vestibular schwannoma, vestibular complaints were significant predictors for becoming dependant of disability pension.
doi_str_mv 10.1016/j.wneu.2013.03.069
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Methods A total of 434 consecutive patients were followed at regular intervals. Data on symptoms were scored prospectively and dichotomized by visual analog scales for tinnitus and vertigo. Study design is retrospective. Hearing acuity was scored according to the Gardner-Robertson scale, and unsteadiness was measured on a balance platform. Patients were asked about working status, and scored as receiving governmental compensation for disability. Results Two hundred six patients were eligible for study. Of these, one died and nine were lost to follow-up. Ninety-seven patients received conservative management, 49 patients recieved gamma knife radiosurgery, and 50 patients were treated by microsurgery. Mean follow-up time was 58.7 months (range, 20–132 months). There was a significant increase in the number of individuals receiving compensation during the study period ( P &lt; 0.0001). At baseline, the proportion of pension receivers was within same range as that of the age- and sex-matched Norwegian population (5.61% vs. 6.91%; case-control odds ratio, 0.82; 95% confidence interval 0.45–1.49; P  = 0.51, not significant). At the final time point, the increase in the number of receivers deviated significantly from the reference population (case-control odds ratio, 3.80; 95% confidence interval 2.71–5.33; P ≤ 0.001). Examining symptoms at first presentation as predictors of future dependence revealed that vertigo and higher mean age were associated with a higher risk ( P &lt; 0.001 and P  = 0.015, respectively). No other symptoms were predictive of dependence. Conclusions In a prospectively followed cohort of Norwegian patients with vestibular schwannoma, vestibular complaints were significant predictors for becoming dependant of disability pension.</description><identifier>ISSN: 1878-8750</identifier><identifier>EISSN: 1878-8769</identifier><identifier>DOI: 10.1016/j.wneu.2013.03.069</identifier><identifier>PMID: 23548845</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acoustic neurinoma ; Adolescent ; Adult ; Age Factors ; Case-Control Studies ; Confidence Intervals ; Disability Evaluation ; Disability pension ; Employment ; Female ; Follow-Up Studies ; Hearing Tests ; Humans ; Male ; Microsurgery ; Middle Aged ; Neurologic Examination ; Neuroma, Acoustic - complications ; Neuroma, Acoustic - physiopathology ; Neuroma, Acoustic - surgery ; Neurosurgery ; Neurosurgical Procedures ; Norway - epidemiology ; Odds Ratio ; Postural Balance ; Prospective Studies ; Radiosurgery ; Retrospective Studies ; Sex Factors ; Treatment Outcome ; Vertigo - etiology ; Vertigo - physiopathology ; Vestibular schwannoma ; Young Adult</subject><ispartof>World neurosurgery, 2013-12, Vol.80 (6), p.e301-e305</ispartof><rights>Elsevier Inc.</rights><rights>2013 Elsevier Inc.</rights><rights>Copyright © 2013 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-90686e3b011f19f14560577e7fa7b6c827f27470e2292e75fc7b741b9025a6bc3</citedby><cites>FETCH-LOGICAL-c411t-90686e3b011f19f14560577e7fa7b6c827f27470e2292e75fc7b741b9025a6bc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.wneu.2013.03.069$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23548845$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Breivik, Cathrine Nansdal</creatorcontrib><creatorcontrib>Nilsen, Roy Miodini</creatorcontrib><creatorcontrib>Myrseth, Erling</creatorcontrib><creatorcontrib>Finnkirk, Monica Katrine</creatorcontrib><creatorcontrib>Lund-Johansen, Morten</creatorcontrib><title>Working Disability in Norwegian Patients with Vestibular Schwannoma: Vertigo Predicts Future Dependence</title><title>World neurosurgery</title><addtitle>World Neurosurg</addtitle><description>Objective We examined whether reduced hearing, tinnitus, dizziness, and unsteadiness affected the patients' ability to maintain work within a time frame of 2–10 years after diagnosis. Methods A total of 434 consecutive patients were followed at regular intervals. Data on symptoms were scored prospectively and dichotomized by visual analog scales for tinnitus and vertigo. Study design is retrospective. Hearing acuity was scored according to the Gardner-Robertson scale, and unsteadiness was measured on a balance platform. Patients were asked about working status, and scored as receiving governmental compensation for disability. Results Two hundred six patients were eligible for study. Of these, one died and nine were lost to follow-up. Ninety-seven patients received conservative management, 49 patients recieved gamma knife radiosurgery, and 50 patients were treated by microsurgery. Mean follow-up time was 58.7 months (range, 20–132 months). There was a significant increase in the number of individuals receiving compensation during the study period ( P &lt; 0.0001). At baseline, the proportion of pension receivers was within same range as that of the age- and sex-matched Norwegian population (5.61% vs. 6.91%; case-control odds ratio, 0.82; 95% confidence interval 0.45–1.49; P  = 0.51, not significant). At the final time point, the increase in the number of receivers deviated significantly from the reference population (case-control odds ratio, 3.80; 95% confidence interval 2.71–5.33; P ≤ 0.001). Examining symptoms at first presentation as predictors of future dependence revealed that vertigo and higher mean age were associated with a higher risk ( P &lt; 0.001 and P  = 0.015, respectively). No other symptoms were predictive of dependence. Conclusions In a prospectively followed cohort of Norwegian patients with vestibular schwannoma, vestibular complaints were significant predictors for becoming dependant of disability pension.</description><subject>Acoustic neurinoma</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Case-Control Studies</subject><subject>Confidence Intervals</subject><subject>Disability Evaluation</subject><subject>Disability pension</subject><subject>Employment</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hearing Tests</subject><subject>Humans</subject><subject>Male</subject><subject>Microsurgery</subject><subject>Middle Aged</subject><subject>Neurologic Examination</subject><subject>Neuroma, Acoustic - complications</subject><subject>Neuroma, Acoustic - physiopathology</subject><subject>Neuroma, Acoustic - surgery</subject><subject>Neurosurgery</subject><subject>Neurosurgical Procedures</subject><subject>Norway - epidemiology</subject><subject>Odds Ratio</subject><subject>Postural Balance</subject><subject>Prospective Studies</subject><subject>Radiosurgery</subject><subject>Retrospective Studies</subject><subject>Sex Factors</subject><subject>Treatment Outcome</subject><subject>Vertigo - etiology</subject><subject>Vertigo - physiopathology</subject><subject>Vestibular schwannoma</subject><subject>Young Adult</subject><issn>1878-8750</issn><issn>1878-8769</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kV1rFDEUhoMottT-AS8kl97sNh-TZEZEkNZWoWihflyGTObM9mxnM9sk47L_3gxbe-GF4UDC4X1fcp5DyGvOlpxxfbZe7gJMS8G4XLJSunlGjnlt6kVtdPP86a3YETlNac3KkbyqjXxJjoRUVV1X6pisfo3xHsOKXmByLQ6Y9xQD_TrGHazQBXrjMkLIie4w39GfkDK20-AivfV3OxfCuHHvSjtmXI30JkKHvogvpzxFoBewhdBB8PCKvOjdkOD08T4hPy4_fT__vLj-dvXl_OP1wlec50XDdK1Btozznjc9r5RmyhgwvTOt9rUwvTCVYSBEI8Co3pvWVLxtmFBOt16ekLeH3G0cH6byW7vB5GEYXIBxSpZXWksjZWOKVBykPo4pRejtNuLGxb3lzM6M7drOjO3M2LJSuimmN4_5U7uB7snyl2gRvD8IoEz5GyHa5HEm0GEEn2034v_zP_xj9wMG9G64hz2k9TjFUPhZbpOwzN7OW56XzCVjSish_wDnQaJ1</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Breivik, Cathrine Nansdal</creator><creator>Nilsen, Roy Miodini</creator><creator>Myrseth, Erling</creator><creator>Finnkirk, Monica Katrine</creator><creator>Lund-Johansen, Morten</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20131201</creationdate><title>Working Disability in Norwegian Patients with Vestibular Schwannoma: Vertigo Predicts Future Dependence</title><author>Breivik, Cathrine Nansdal ; Nilsen, Roy Miodini ; Myrseth, Erling ; Finnkirk, Monica Katrine ; Lund-Johansen, Morten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-90686e3b011f19f14560577e7fa7b6c827f27470e2292e75fc7b741b9025a6bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acoustic neurinoma</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Case-Control Studies</topic><topic>Confidence Intervals</topic><topic>Disability Evaluation</topic><topic>Disability pension</topic><topic>Employment</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hearing Tests</topic><topic>Humans</topic><topic>Male</topic><topic>Microsurgery</topic><topic>Middle Aged</topic><topic>Neurologic Examination</topic><topic>Neuroma, Acoustic - complications</topic><topic>Neuroma, Acoustic - physiopathology</topic><topic>Neuroma, Acoustic - surgery</topic><topic>Neurosurgery</topic><topic>Neurosurgical Procedures</topic><topic>Norway - epidemiology</topic><topic>Odds Ratio</topic><topic>Postural Balance</topic><topic>Prospective Studies</topic><topic>Radiosurgery</topic><topic>Retrospective Studies</topic><topic>Sex Factors</topic><topic>Treatment Outcome</topic><topic>Vertigo - etiology</topic><topic>Vertigo - physiopathology</topic><topic>Vestibular schwannoma</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Breivik, Cathrine Nansdal</creatorcontrib><creatorcontrib>Nilsen, Roy Miodini</creatorcontrib><creatorcontrib>Myrseth, Erling</creatorcontrib><creatorcontrib>Finnkirk, Monica Katrine</creatorcontrib><creatorcontrib>Lund-Johansen, Morten</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>World neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Breivik, Cathrine Nansdal</au><au>Nilsen, Roy Miodini</au><au>Myrseth, Erling</au><au>Finnkirk, Monica Katrine</au><au>Lund-Johansen, Morten</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Working Disability in Norwegian Patients with Vestibular Schwannoma: Vertigo Predicts Future Dependence</atitle><jtitle>World neurosurgery</jtitle><addtitle>World Neurosurg</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>80</volume><issue>6</issue><spage>e301</spage><epage>e305</epage><pages>e301-e305</pages><issn>1878-8750</issn><eissn>1878-8769</eissn><abstract>Objective We examined whether reduced hearing, tinnitus, dizziness, and unsteadiness affected the patients' ability to maintain work within a time frame of 2–10 years after diagnosis. Methods A total of 434 consecutive patients were followed at regular intervals. Data on symptoms were scored prospectively and dichotomized by visual analog scales for tinnitus and vertigo. Study design is retrospective. Hearing acuity was scored according to the Gardner-Robertson scale, and unsteadiness was measured on a balance platform. Patients were asked about working status, and scored as receiving governmental compensation for disability. Results Two hundred six patients were eligible for study. Of these, one died and nine were lost to follow-up. Ninety-seven patients received conservative management, 49 patients recieved gamma knife radiosurgery, and 50 patients were treated by microsurgery. Mean follow-up time was 58.7 months (range, 20–132 months). There was a significant increase in the number of individuals receiving compensation during the study period ( P &lt; 0.0001). At baseline, the proportion of pension receivers was within same range as that of the age- and sex-matched Norwegian population (5.61% vs. 6.91%; case-control odds ratio, 0.82; 95% confidence interval 0.45–1.49; P  = 0.51, not significant). At the final time point, the increase in the number of receivers deviated significantly from the reference population (case-control odds ratio, 3.80; 95% confidence interval 2.71–5.33; P ≤ 0.001). Examining symptoms at first presentation as predictors of future dependence revealed that vertigo and higher mean age were associated with a higher risk ( P &lt; 0.001 and P  = 0.015, respectively). No other symptoms were predictive of dependence. Conclusions In a prospectively followed cohort of Norwegian patients with vestibular schwannoma, vestibular complaints were significant predictors for becoming dependant of disability pension.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>23548845</pmid><doi>10.1016/j.wneu.2013.03.069</doi></addata></record>
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subjects Acoustic neurinoma
Adolescent
Adult
Age Factors
Case-Control Studies
Confidence Intervals
Disability Evaluation
Disability pension
Employment
Female
Follow-Up Studies
Hearing Tests
Humans
Male
Microsurgery
Middle Aged
Neurologic Examination
Neuroma, Acoustic - complications
Neuroma, Acoustic - physiopathology
Neuroma, Acoustic - surgery
Neurosurgery
Neurosurgical Procedures
Norway - epidemiology
Odds Ratio
Postural Balance
Prospective Studies
Radiosurgery
Retrospective Studies
Sex Factors
Treatment Outcome
Vertigo - etiology
Vertigo - physiopathology
Vestibular schwannoma
Young Adult
title Working Disability in Norwegian Patients with Vestibular Schwannoma: Vertigo Predicts Future Dependence
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