The neuroprotective effects of rituximab in rat spinal cord injury model: an immunohistochemical study

In the present study, we investigate the neuroprotective effects of rituximab, a monoclonal antibody directed towards B cell mediated humoral immunity, on a rat spinal cord injury (SCI) model with immunohistochemical methods. Twenty-four rats were used for the study. Rats were divided as control, SC...

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Veröffentlicht in:	Turkish neurosurgery 2013, Vol.23 (6), p.783-790
Hauptverfasser:	Menekse, Guner, Daglioglu, Ergun, Nacar, Osman Arikan, Polat, Ersin, Ozdol, Cagatay, Dalgic, Ali, Take, Gulnur, Okten, Ali Ihsan, Belen, Ahmet Deniz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal, Murine-Derived - pharmacology Antigens, CD20 - metabolism Antineoplastic Agents - pharmacology B-Lymphocytes - drug effects Enzyme-Linked Immunosorbent Assay Immunohistochemistry Interleukin-1 - metabolism Interleukin-6 - metabolism Male Microscopy, Electron, Transmission Neuroprotective Agents Rats Rats, Wistar Rituximab Spinal Cord Injuries - drug therapy Spinal Cord Injuries - pathology Tissue Fixation Tumor Necrosis Factor-alpha - metabolism
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