Quantitative on-line vs. off-line NIR analysis of fluidized bed drying with consideration of the spectral background

Quantitative dehydration studies of dibasic calcium phosphate anhydrous (DCPA) in a small-scale cold-model fluidized bed dryer with process air control were conducted. Near-infrared spectroscopy (NIRS) with partial least squares regression (PLSR) was used to predict DCPAs’ residual moisture content....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2013-11, Vol.85 (3), p.1064-1074
Hauptverfasser:	Heigl, Nicolas, Koller, Daniel M., Glasser, Benjamin J., Muzzio, Fernando J., Khinast, Johannes G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Buffers Calcium Phosphates - chemistry Calibration Chemistry, Pharmaceutical - methods Dibasic calcium phosphate anhydrous Excipients - chemistry Fluidized bed Least-Squares Analysis Multivariate Analysis Near-infrared spectroscopy Off-line On-line Partial least squares regression Polymethyl Methacrylate - chemistry Reference Values Reproducibility of Results Software Spectral background Spectroscopy, Near-Infrared - methods Technology, Pharmaceutical - instrumentation Technology, Pharmaceutical - methods Temperature Time Factors Water - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!