Neuroblastoma Presenting as Persistent Postprandial Emesis in a Neonate
ABSTRACTEarly identification and treatment of neuroblastoma, the most common malignant solid tumor in infants, (Atkinson et al. AJR Am J Roentgenol. 1986;146:113–117; Nuchtern. Semin Pediatr Surg. 2006;15:10–16; Lanzkowsky. Manual of Pediatric Hematology and Oncology. 4th ed. Burlington, MAElsevier...
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| Veröffentlicht in: | Pediatric emergency care 2013-12, Vol.29 (12), p.1273-1275 |
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| creator | Rezaimehr, Yalda Bhargava, Rishi |
| description | ABSTRACTEarly identification and treatment of neuroblastoma, the most common malignant solid tumor in infants, (Atkinson et al. AJR Am J Roentgenol. 1986;146:113–117; Nuchtern. Semin Pediatr Surg. 2006;15:10–16; Lanzkowsky. Manual of Pediatric Hematology and Oncology. 4th ed. Burlington, MAElsevier Academic Press; 2005:530–547) can improve prognosis of this illness. Benign emesis as an initial presentation of infantile neuroblastoma is rare (Isaacs. Fetal Pediatr Pathol. 2007;26:177–184). We report a case of a 17-day-old healthy male who presented to the emergency department with persistent, nonprojectile emesis after feedings. A diagnosis of nonresectable stage IV thoracoabdominal neuroblastoma with invasion to the spine was made. We concluded that oncological processes, such as neuroblastoma, should be included in the differential diagnosis of persistent emesis in the neonatal period. Emergency physicians may have the opportunity to detect neuroblastoma earlier by contemplating a broader differential diagnosis of a vomiting infant and initiating the appropriate workup in the emergency department. |
| doi_str_mv | 10.1097/PEC.0000000000000029 |
| format | Article |
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Emergency physicians may have the opportunity to detect neuroblastoma earlier by contemplating a broader differential diagnosis of a vomiting infant and initiating the appropriate workup in the emergency department.</description><identifier>ISSN: 0749-5161</identifier><identifier>EISSN: 1535-1815</identifier><identifier>DOI: 10.1097/PEC.0000000000000029</identifier><identifier>PMID: 24300469</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Biomarkers, Tumor - urine ; Cell Differentiation ; Dexamethasone - administration & dosage ; Diagnosis, Differential ; Emergencies ; Humans ; Infant, Newborn ; Male ; Mediastinal Neoplasms - complications ; Mediastinal Neoplasms - diagnosis ; Mediastinal Neoplasms - diagnostic imaging ; Mediastinal Neoplasms - drug therapy ; Mediastinal Neoplasms - pathology ; Neoplasm Invasiveness ; Neoplasm Staging ; Neoplasm, Residual ; Neuroblastoma - complications ; Neuroblastoma - diagnosis ; Neuroblastoma - diagnostic imaging ; Neuroblastoma - drug therapy ; Neuroblastoma - pathology ; Postprandial Period ; Spinal Cord Compression - etiology ; Thoracic Vertebrae ; Ultrasonography ; Vomiting - etiology</subject><ispartof>Pediatric emergency care, 2013-12, Vol.29 (12), p.1273-1275</ispartof><rights>2013 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3526-5499674f4d1c3ddd886d4680a97dfcb7b8c1205c29da086b4f96dc00398f89563</citedby><cites>FETCH-LOGICAL-c3526-5499674f4d1c3ddd886d4680a97dfcb7b8c1205c29da086b4f96dc00398f89563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24300469$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rezaimehr, Yalda</creatorcontrib><creatorcontrib>Bhargava, Rishi</creatorcontrib><title>Neuroblastoma Presenting as Persistent Postprandial Emesis in a Neonate</title><title>Pediatric emergency care</title><addtitle>Pediatr Emerg Care</addtitle><description>ABSTRACTEarly identification and treatment of neuroblastoma, the most common malignant solid tumor in infants, (Atkinson et al. AJR Am J Roentgenol. 1986;146:113–117; Nuchtern. Semin Pediatr Surg. 2006;15:10–16; Lanzkowsky. Manual of Pediatric Hematology and Oncology. 4th ed. Burlington, MAElsevier Academic Press; 2005:530–547) can improve prognosis of this illness. Benign emesis as an initial presentation of infantile neuroblastoma is rare (Isaacs. Fetal Pediatr Pathol. 2007;26:177–184). We report a case of a 17-day-old healthy male who presented to the emergency department with persistent, nonprojectile emesis after feedings. A diagnosis of nonresectable stage IV thoracoabdominal neuroblastoma with invasion to the spine was made. We concluded that oncological processes, such as neuroblastoma, should be included in the differential diagnosis of persistent emesis in the neonatal period. Emergency physicians may have the opportunity to detect neuroblastoma earlier by contemplating a broader differential diagnosis of a vomiting infant and initiating the appropriate workup in the emergency department.</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Biomarkers, Tumor - urine</subject><subject>Cell Differentiation</subject><subject>Dexamethasone - administration & dosage</subject><subject>Diagnosis, Differential</subject><subject>Emergencies</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Mediastinal Neoplasms - complications</subject><subject>Mediastinal Neoplasms - diagnosis</subject><subject>Mediastinal Neoplasms - diagnostic imaging</subject><subject>Mediastinal Neoplasms - drug therapy</subject><subject>Mediastinal Neoplasms - pathology</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Staging</subject><subject>Neoplasm, Residual</subject><subject>Neuroblastoma - complications</subject><subject>Neuroblastoma - diagnosis</subject><subject>Neuroblastoma - diagnostic imaging</subject><subject>Neuroblastoma - drug therapy</subject><subject>Neuroblastoma - pathology</subject><subject>Postprandial Period</subject><subject>Spinal Cord Compression - etiology</subject><subject>Thoracic Vertebrae</subject><subject>Ultrasonography</subject><subject>Vomiting - etiology</subject><issn>0749-5161</issn><issn>1535-1815</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkM1OwzAQhC0EoqXwBgjlyCVlHf_EPqKqFKSq5ADnyIkdGkjiYieqeHtMW0Cwl5VmZ2e1H0KXGKYYZHqTzWdT-FOJPEJjzAiLscDsGI0hpTJmmOMROvP-FSAMCTlFo4QSAMrlGC1WZnC2aJTvbauizBlvur7uXiLlo8w4X_s-CFFmfb9xqtO1aqJ5a4Ie1V2kopWxnerNOTqpVOPNxaFP0PPd_Gl2Hy8fFw-z22VcEpbwmFEpeUorqnFJtNZCcE25ACVTXZVFWogSJ8DKRGoFghe0klyXAESKSkjGyQRd73M3zr4Pxvd5W_vSNI3qjB18jilnOGVCyGCle2vprPfOVPnG1a1yHzmG_AthHhDm_xGGtavDhaFojf5Z-mb2m7u1TR8IvTXD1rh8bVTTr3d5nHEWJ4BJ-AUg3knkE3BHers</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Rezaimehr, Yalda</creator><creator>Bhargava, Rishi</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201312</creationdate><title>Neuroblastoma Presenting as Persistent Postprandial Emesis in a Neonate</title><author>Rezaimehr, Yalda ; Bhargava, Rishi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3526-5499674f4d1c3ddd886d4680a97dfcb7b8c1205c29da086b4f96dc00398f89563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Biomarkers, Tumor - urine</topic><topic>Cell Differentiation</topic><topic>Dexamethasone - administration & dosage</topic><topic>Diagnosis, Differential</topic><topic>Emergencies</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Mediastinal Neoplasms - complications</topic><topic>Mediastinal Neoplasms - diagnosis</topic><topic>Mediastinal Neoplasms - diagnostic imaging</topic><topic>Mediastinal Neoplasms - drug therapy</topic><topic>Mediastinal Neoplasms - pathology</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Staging</topic><topic>Neoplasm, Residual</topic><topic>Neuroblastoma - complications</topic><topic>Neuroblastoma - diagnosis</topic><topic>Neuroblastoma - diagnostic imaging</topic><topic>Neuroblastoma - drug therapy</topic><topic>Neuroblastoma - pathology</topic><topic>Postprandial Period</topic><topic>Spinal Cord Compression - etiology</topic><topic>Thoracic Vertebrae</topic><topic>Ultrasonography</topic><topic>Vomiting - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rezaimehr, Yalda</creatorcontrib><creatorcontrib>Bhargava, Rishi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric emergency care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rezaimehr, Yalda</au><au>Bhargava, Rishi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neuroblastoma Presenting as Persistent Postprandial Emesis in a Neonate</atitle><jtitle>Pediatric emergency care</jtitle><addtitle>Pediatr Emerg Care</addtitle><date>2013-12</date><risdate>2013</risdate><volume>29</volume><issue>12</issue><spage>1273</spage><epage>1275</epage><pages>1273-1275</pages><issn>0749-5161</issn><eissn>1535-1815</eissn><abstract>ABSTRACTEarly identification and treatment of neuroblastoma, the most common malignant solid tumor in infants, (Atkinson et al. AJR Am J Roentgenol. 1986;146:113–117; Nuchtern. Semin Pediatr Surg. 2006;15:10–16; Lanzkowsky. Manual of Pediatric Hematology and Oncology. 4th ed. Burlington, MAElsevier Academic Press; 2005:530–547) can improve prognosis of this illness. Benign emesis as an initial presentation of infantile neuroblastoma is rare (Isaacs. Fetal Pediatr Pathol. 2007;26:177–184). We report a case of a 17-day-old healthy male who presented to the emergency department with persistent, nonprojectile emesis after feedings. A diagnosis of nonresectable stage IV thoracoabdominal neuroblastoma with invasion to the spine was made. We concluded that oncological processes, such as neuroblastoma, should be included in the differential diagnosis of persistent emesis in the neonatal period. 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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomarkers, Tumor - urine Cell Differentiation Dexamethasone - administration & dosage Diagnosis, Differential Emergencies Humans Infant, Newborn Male Mediastinal Neoplasms - complications Mediastinal Neoplasms - diagnosis Mediastinal Neoplasms - diagnostic imaging Mediastinal Neoplasms - drug therapy Mediastinal Neoplasms - pathology Neoplasm Invasiveness Neoplasm Staging Neoplasm, Residual Neuroblastoma - complications Neuroblastoma - diagnosis Neuroblastoma - diagnostic imaging Neuroblastoma - drug therapy Neuroblastoma - pathology Postprandial Period Spinal Cord Compression - etiology Thoracic Vertebrae Ultrasonography Vomiting - etiology |
| title | Neuroblastoma Presenting as Persistent Postprandial Emesis in a Neonate |
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