Disease susceptibility in California sea lions
Evidence from a wide range of research has indicated that inbreeding within animal populations can lead to substantial increases in their susceptibility to pathogens. Findings are reported from a study investigating rescued California sea lions (Zalophus californianus) impacted by a variety of diffe...
Gespeichert in:
Veröffentlicht in: | Nature (London) 2003-03, Vol.422 (6927), p.35-35 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 35 |
---|---|
container_issue | 6927 |
container_start_page | 35 |
container_title | Nature (London) |
container_volume | 422 |
creator | Acevedo-Whitehouse, Karina Gulland, Frances Greig, Denise Amos, William |
description | Evidence from a wide range of research has indicated that inbreeding within animal populations can lead to substantial increases in their susceptibility to pathogens. Findings are reported from a study investigating rescued California sea lions (Zalophus californianus) impacted by a variety of different pathogens. Results from the study indicated that sick animals typically exhibited a higher-than-normal level of parental relatedness. These findings suggested that mortality patterns in natural populations of wild animals may not be entirely random. Evidence also suggested that inbred individuals may sesrve as more effective reservoirs of infectious agents. Implications of these findings for the debate over the role of genetics in demography and conservation are discussed. |
doi_str_mv | 10.1038/422035a |
format | Article |
fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_14651269</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>887915811</sourcerecordid><originalsourceid>FETCH-LOGICAL-p244t-b69d666e955c28c78188321ef1a7e0fe2e8ccf4b0533156c1b79444924985bcb3</originalsourceid><addsrcrecordid>eNpdj81KxDAURoMoOI7iKxQX7jrem9z8LaU6Kgy40XVJYgoZYlubduHbW9CVq29z-DiHsWuEHYIwd8Q5COlO2AZJq5qU0adsA8BNDUaoc3ZRyhEAJGrasN1DKtGVWJWlhDjOyaec5u8q9VXjcuqGqU-uWpEqp6Evl-ysc7nEq7_dsvf941vzXB9en16a-0M9cqK59sp-KKWilTJwE7RBYwTH2KHTEbrIowmhIw9SCJQqoNeWiCwna6QPXmzZ7e_vOA1fSyxz-5lWv5xdH4eltEhKIld2BW_-gcdhmfrVreVAEuxaKn4ArGdPZg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>204509000</pqid></control><display><type>article</type><title>Disease susceptibility in California sea lions</title><source>Nature</source><source>Alma/SFX Local Collection</source><creator>Acevedo-Whitehouse, Karina ; Gulland, Frances ; Greig, Denise ; Amos, William</creator><creatorcontrib>Acevedo-Whitehouse, Karina ; Gulland, Frances ; Greig, Denise ; Amos, William</creatorcontrib><description>Evidence from a wide range of research has indicated that inbreeding within animal populations can lead to substantial increases in their susceptibility to pathogens. Findings are reported from a study investigating rescued California sea lions (Zalophus californianus) impacted by a variety of different pathogens. Results from the study indicated that sick animals typically exhibited a higher-than-normal level of parental relatedness. These findings suggested that mortality patterns in natural populations of wild animals may not be entirely random. Evidence also suggested that inbred individuals may sesrve as more effective reservoirs of infectious agents. Implications of these findings for the debate over the role of genetics in demography and conservation are discussed.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/422035a</identifier><identifier>CODEN: NATUAS</identifier><language>eng</language><publisher>London: Nature Publishing Group</publisher><subject>Bacterial infections ; Cancer ; Generalized linear models ; Infections ; Infectious diseases ; Marine mammals ; Mortality ; Pathogens ; Sea lions ; Variance analysis</subject><ispartof>Nature (London), 2003-03, Vol.422 (6927), p.35-35</ispartof><rights>Copyright Nature Publishing Group Mar 6, 2003</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Acevedo-Whitehouse, Karina</creatorcontrib><creatorcontrib>Gulland, Frances</creatorcontrib><creatorcontrib>Greig, Denise</creatorcontrib><creatorcontrib>Amos, William</creatorcontrib><title>Disease susceptibility in California sea lions</title><title>Nature (London)</title><description>Evidence from a wide range of research has indicated that inbreeding within animal populations can lead to substantial increases in their susceptibility to pathogens. Findings are reported from a study investigating rescued California sea lions (Zalophus californianus) impacted by a variety of different pathogens. Results from the study indicated that sick animals typically exhibited a higher-than-normal level of parental relatedness. These findings suggested that mortality patterns in natural populations of wild animals may not be entirely random. Evidence also suggested that inbred individuals may sesrve as more effective reservoirs of infectious agents. Implications of these findings for the debate over the role of genetics in demography and conservation are discussed.</description><subject>Bacterial infections</subject><subject>Cancer</subject><subject>Generalized linear models</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Marine mammals</subject><subject>Mortality</subject><subject>Pathogens</subject><subject>Sea lions</subject><subject>Variance analysis</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdj81KxDAURoMoOI7iKxQX7jrem9z8LaU6Kgy40XVJYgoZYlubduHbW9CVq29z-DiHsWuEHYIwd8Q5COlO2AZJq5qU0adsA8BNDUaoc3ZRyhEAJGrasN1DKtGVWJWlhDjOyaec5u8q9VXjcuqGqU-uWpEqp6Evl-ysc7nEq7_dsvf941vzXB9en16a-0M9cqK59sp-KKWilTJwE7RBYwTH2KHTEbrIowmhIw9SCJQqoNeWiCwna6QPXmzZ7e_vOA1fSyxz-5lWv5xdH4eltEhKIld2BW_-gcdhmfrVreVAEuxaKn4ArGdPZg</recordid><startdate>20030306</startdate><enddate>20030306</enddate><creator>Acevedo-Whitehouse, Karina</creator><creator>Gulland, Frances</creator><creator>Greig, Denise</creator><creator>Amos, William</creator><general>Nature Publishing Group</general><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T5</scope><scope>7TG</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>R05</scope><scope>RC3</scope><scope>S0X</scope><scope>SOI</scope></search><sort><creationdate>20030306</creationdate><title>Disease susceptibility in California sea lions</title><author>Acevedo-Whitehouse, Karina ; Gulland, Frances ; Greig, Denise ; Amos, William</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p244t-b69d666e955c28c78188321ef1a7e0fe2e8ccf4b0533156c1b79444924985bcb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Bacterial infections</topic><topic>Cancer</topic><topic>Generalized linear models</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Marine mammals</topic><topic>Mortality</topic><topic>Pathogens</topic><topic>Sea lions</topic><topic>Variance analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Acevedo-Whitehouse, Karina</creatorcontrib><creatorcontrib>Gulland, Frances</creatorcontrib><creatorcontrib>Greig, Denise</creatorcontrib><creatorcontrib>Amos, William</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>University of Michigan</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>Environment Abstracts</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Acevedo-Whitehouse, Karina</au><au>Gulland, Frances</au><au>Greig, Denise</au><au>Amos, William</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disease susceptibility in California sea lions</atitle><jtitle>Nature (London)</jtitle><date>2003-03-06</date><risdate>2003</risdate><volume>422</volume><issue>6927</issue><spage>35</spage><epage>35</epage><pages>35-35</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><coden>NATUAS</coden><abstract>Evidence from a wide range of research has indicated that inbreeding within animal populations can lead to substantial increases in their susceptibility to pathogens. Findings are reported from a study investigating rescued California sea lions (Zalophus californianus) impacted by a variety of different pathogens. Results from the study indicated that sick animals typically exhibited a higher-than-normal level of parental relatedness. These findings suggested that mortality patterns in natural populations of wild animals may not be entirely random. Evidence also suggested that inbred individuals may sesrve as more effective reservoirs of infectious agents. Implications of these findings for the debate over the role of genetics in demography and conservation are discussed.</abstract><cop>London</cop><pub>Nature Publishing Group</pub><doi>10.1038/422035a</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0028-0836 |
ispartof | Nature (London), 2003-03, Vol.422 (6927), p.35-35 |
issn | 0028-0836 1476-4687 |
language | eng |
recordid | cdi_proquest_miscellaneous_14651269 |
source | Nature; Alma/SFX Local Collection |
subjects | Bacterial infections Cancer Generalized linear models Infections Infectious diseases Marine mammals Mortality Pathogens Sea lions Variance analysis |
title | Disease susceptibility in California sea lions |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T08%3A49%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Disease%20susceptibility%20in%20California%20sea%20lions&rft.jtitle=Nature%20(London)&rft.au=Acevedo-Whitehouse,%20Karina&rft.date=2003-03-06&rft.volume=422&rft.issue=6927&rft.spage=35&rft.epage=35&rft.pages=35-35&rft.issn=0028-0836&rft.eissn=1476-4687&rft.coden=NATUAS&rft_id=info:doi/10.1038/422035a&rft_dat=%3Cproquest%3E887915811%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=204509000&rft_id=info:pmid/&rfr_iscdi=true |