Role of Preablation Neutrophil/Lymphocyte Ratio on Outcomes of Cryoballoon-Based Atrial Fibrillation Ablation

Role of Preablation Neutrophil/Lymphocyte Ratio on Outcomes of Cryoballoon-Based Atrial Fibrillation Ablation

The neutrophil/lymphocyte ratio (NLR) has recently emerged as better indicator of inflammation and oxidative stress and has been widely studied in several cardiovascular diseases. In the present study, we evaluated the role of the preablation NLR in atrial fibrillation (AF) recurrence after cryoball...

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Veröffentlicht in:The American journal of cardiology 2013-08, Vol.112 (4), p.513-519
Hauptverfasser: Canpolat, Uğur, MD, Aytemir, Kudret, MD, Yorgun, Hikmet, MD, Şahiner, Levent, MD, Kaya, Ergün Barış, MD, Kabakçı, Giray, MD, Tokgözoğlu, Lale, MD, Oto, Ali, MD
Format: Artikel
Sprache:eng
Schlagworte:
Age
Anticoagulants - administration & dosage
Area Under Curve
Atrial Fibrillation - blood
Atrial Fibrillation - surgery
Blood clots
C-Reactive Protein - metabolism
Cardiac arrhythmia
Cardiovascular
Cardiovascular disease
Catheters
Comorbidity
Coronary vessels
Cryosurgery - instrumentation
Cryosurgery - methods
Family medical history
Female
Heart attacks
Humans
Lymphocytes
Lymphocytes - pathology
Male
Middle Aged
Neutrophils - pathology
Oxidative Stress
Prospective Studies
Proteins
Recurrence
Regression Analysis
Risk Factors
ROC Curve
Sensitivity and Specificity
Treatment Outcome
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Zusammenfassung:The neutrophil/lymphocyte ratio (NLR) has recently emerged as better indicator of inflammation and oxidative stress and has been widely studied in several cardiovascular diseases. In the present study, we evaluated the role of the preablation NLR in atrial fibrillation (AF) recurrence after cryoballoon-based catheter ablation. A total of 251 patients (47.8% women, age 54.12 ± 10.9 years, 80.1% with paroxysmal AF) with symptomatic AF underwent cryoablation. At a mean follow-up of 19.0 ± 6.6 months, 60 patients (23.9%) had developed AF recurrence. The patients who developed AF recurrence had had a greater preablation NLR (3.53 ± 0.95 vs 2.65 ± 0.23, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2013.04.015