Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling: e1003652

Herpes Simplex Virus type 1 (HSV-1) has evolved to disable the cellular DNA damage response kinase, ATR. We have previously shown that HSV-1-infected cells are unable to phosphorylate the ATR substrate Chk1, even under conditions in which replication forks are stalled. Here we report that the HSV-1...

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Veröffentlicht in:	PLoS pathogens 2013-10, Vol.9 (10)
Hauptverfasser:	Mohni, Kareem N, Smith, Samantha, Dee, Alexander R, Schumacher, April J, Weller, Sandra K
Format:	Artikel
Sprache:	eng
Schlagworte:	Deoxyribonucleic acid DNA DNA damage DNA repair Herpes simplex virus 1 Kinases
Online-Zugang:	Volltext
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