Dectin-2-Dependent NKT Cell Activation and Serotype-Specific Antibody Production in Mice Immunized with Pneumococcal Polysaccharide Vaccine: e78611

Although thymus-independent type 2 antigens generally do not undergo Ig class switching from IgM to IgG, pneumococcal polysaccharide vaccine (PPV) induces the production of serotype-specific IgG. How this happens remains unclear, however. In the present study, PPV immunization induced production of...

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Veröffentlicht in:PloS one 2013-10, Vol.8 (10)
Hauptverfasser: Miyasaka, Tomomitsu, Akahori, Yukiko, Toyama, Masahiko, Miyamura, Namiko, Ishii, Keiko, Saijo, Shinobu, Iwakura, Yoichiro, Kinjo, Yuki, Miyazaki, Yoshitsugu, Oishi, Kazunori
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