First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry
The development of a multi-method for the detection of seven allergens based on liquid chromatography and triple-quadrupole tandem mass spectrometry in multiple reaction mode is described. It is based on extraction of the allergenic proteins from a food matrix, followed by enzymatic digestion with t...
Gespeichert in:
| Veröffentlicht in: | Journal of Chromatography A 2011-02, Vol.1218 (7), p.938-943 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 943 |
|---|---|
| container_issue | 7 |
| container_start_page | 938 |
| container_title | Journal of Chromatography A |
| container_volume | 1218 |
| creator | Heick, J. Fischer, M. Pöpping, B. |
| description | The development of a multi-method for the detection of seven allergens based on liquid chromatography and triple-quadrupole tandem mass spectrometry in multiple reaction mode is described. It is based on extraction of the allergenic proteins from a food matrix, followed by enzymatic digestion with trypsin. The chosen marker peptides were implemented into one method that is capable of the simultaneous detection of milk, egg, soy, hazelnut, peanut, walnut and almond. This method has been used to detect all seven allergenic commodities from incurred reference bread material, which was baked according to a standard recipe from the baking industry. Detected concentrations ranged from 10 to 1000μg/g, demonstrating that the mass spectrometric based method is a useful tool for allergen screening. |
| doi_str_mv | 10.1016/j.chroma.2010.12.067 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1464503390</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0021967310017619</els_id><sourcerecordid>1464503390</sourcerecordid><originalsourceid>FETCH-LOGICAL-c424t-ab32f8ef9bd853650d5bdabdbb45dc31774894473bf1c7b49aa18d243e4faf163</originalsourceid><addsrcrecordid>eNp9kEuLFDEURoMoTjv6D0SyEdx0m1dVqjaCDI4KA250HfK46U5TVenJTQ30v7eaanXn6sLlfPdxCHnL2Y4z3n487vyh5NHuBLu0xI61-hnZ8E7LrdS6e042jAm-7Vstb8grxCNjXDMtXpIbwYXQSnQbgvepYKXoC8CUpj0doR5yoDEXWg9AMY3zUO0EeUYaoIKvKU80R4rwBBO1wwBlDxNSd6ZDepxToOtdNe-LPR3OdLSIFE9LcmlDLefX5EW0A8Kba70lv-6__Lz7tn348fX73eeHrVdC1a11UsQOYu9C18i2YaFxwbrgnGqCl1xr1fVKaeki99qp3lreBaEkqGgjb-Ut-bDOPZX8OANWMyb0MAzrO4arVjVMyp4tqFpRXzJigWhOJY22nA1n5qLbHM36lrnoNlyYRfcSe3fdMLsRwt_QH78L8P4KWPR2iMVOPuE_Tnaia9p-4T6tHCw-nhIUgz7B5CGksogzIaf_X_IbrsqjGA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1464503390</pqid></control><display><type>article</type><title>First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Heick, J. ; Fischer, M. ; Pöpping, B.</creator><creatorcontrib>Heick, J. ; Fischer, M. ; Pöpping, B.</creatorcontrib><description>The development of a multi-method for the detection of seven allergens based on liquid chromatography and triple-quadrupole tandem mass spectrometry in multiple reaction mode is described. It is based on extraction of the allergenic proteins from a food matrix, followed by enzymatic digestion with trypsin. The chosen marker peptides were implemented into one method that is capable of the simultaneous detection of milk, egg, soy, hazelnut, peanut, walnut and almond. This method has been used to detect all seven allergenic commodities from incurred reference bread material, which was baked according to a standard recipe from the baking industry. Detected concentrations ranged from 10 to 1000μg/g, demonstrating that the mass spectrometric based method is a useful tool for allergen screening.</description><identifier>ISSN: 0021-9673</identifier><identifier>EISSN: 1873-3778</identifier><identifier>DOI: 10.1016/j.chroma.2010.12.067</identifier><identifier>PMID: 21227428</identifier><identifier>CODEN: JOCRAM</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Allergen ; Allergens - analysis ; Allergens - chemistry ; Amino Acid Sequence ; Animals ; Arachis hypogaea ; Biological and medical sciences ; Bread ; Bread - analysis ; Cereal and baking product industries ; Chromatography, Liquid - methods ; Corylus ; Eggs - analysis ; Food Analysis - methods ; Food industries ; Fundamental and applied biological sciences. Psychology ; General aspects ; Immunopathology ; Incurred reference material ; Juglans ; Liquid chromatography/tandem mass spectrometry ; Medical sciences ; Milk - chemistry ; Molecular Sequence Data ; Multi-method ; Multiple reaction mode (MRM) ; Nuts - chemistry ; Peptides - analysis ; Peptides - chemistry ; Prunus dulcis ; Soy Foods - analysis ; Tandem Mass Spectrometry - methods</subject><ispartof>Journal of Chromatography A, 2011-02, Vol.1218 (7), p.938-943</ispartof><rights>2010 Elsevier B.V.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-ab32f8ef9bd853650d5bdabdbb45dc31774894473bf1c7b49aa18d243e4faf163</citedby><cites>FETCH-LOGICAL-c424t-ab32f8ef9bd853650d5bdabdbb45dc31774894473bf1c7b49aa18d243e4faf163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chroma.2010.12.067$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23828569$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21227428$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heick, J.</creatorcontrib><creatorcontrib>Fischer, M.</creatorcontrib><creatorcontrib>Pöpping, B.</creatorcontrib><title>First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry</title><title>Journal of Chromatography A</title><addtitle>J Chromatogr A</addtitle><description>The development of a multi-method for the detection of seven allergens based on liquid chromatography and triple-quadrupole tandem mass spectrometry in multiple reaction mode is described. It is based on extraction of the allergenic proteins from a food matrix, followed by enzymatic digestion with trypsin. The chosen marker peptides were implemented into one method that is capable of the simultaneous detection of milk, egg, soy, hazelnut, peanut, walnut and almond. This method has been used to detect all seven allergenic commodities from incurred reference bread material, which was baked according to a standard recipe from the baking industry. Detected concentrations ranged from 10 to 1000μg/g, demonstrating that the mass spectrometric based method is a useful tool for allergen screening.</description><subject>Allergen</subject><subject>Allergens - analysis</subject><subject>Allergens - chemistry</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Arachis hypogaea</subject><subject>Biological and medical sciences</subject><subject>Bread</subject><subject>Bread - analysis</subject><subject>Cereal and baking product industries</subject><subject>Chromatography, Liquid - methods</subject><subject>Corylus</subject><subject>Eggs - analysis</subject><subject>Food Analysis - methods</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Immunopathology</subject><subject>Incurred reference material</subject><subject>Juglans</subject><subject>Liquid chromatography/tandem mass spectrometry</subject><subject>Medical sciences</subject><subject>Milk - chemistry</subject><subject>Molecular Sequence Data</subject><subject>Multi-method</subject><subject>Multiple reaction mode (MRM)</subject><subject>Nuts - chemistry</subject><subject>Peptides - analysis</subject><subject>Peptides - chemistry</subject><subject>Prunus dulcis</subject><subject>Soy Foods - analysis</subject><subject>Tandem Mass Spectrometry - methods</subject><issn>0021-9673</issn><issn>1873-3778</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEuLFDEURoMoTjv6D0SyEdx0m1dVqjaCDI4KA250HfK46U5TVenJTQ30v7eaanXn6sLlfPdxCHnL2Y4z3n487vyh5NHuBLu0xI61-hnZ8E7LrdS6e042jAm-7Vstb8grxCNjXDMtXpIbwYXQSnQbgvepYKXoC8CUpj0doR5yoDEXWg9AMY3zUO0EeUYaoIKvKU80R4rwBBO1wwBlDxNSd6ZDepxToOtdNe-LPR3OdLSIFE9LcmlDLefX5EW0A8Kba70lv-6__Lz7tn348fX73eeHrVdC1a11UsQOYu9C18i2YaFxwbrgnGqCl1xr1fVKaeki99qp3lreBaEkqGgjb-Ut-bDOPZX8OANWMyb0MAzrO4arVjVMyp4tqFpRXzJigWhOJY22nA1n5qLbHM36lrnoNlyYRfcSe3fdMLsRwt_QH78L8P4KWPR2iMVOPuE_Tnaia9p-4T6tHCw-nhIUgz7B5CGksogzIaf_X_IbrsqjGA</recordid><startdate>20110218</startdate><enddate>20110218</enddate><creator>Heick, J.</creator><creator>Fischer, M.</creator><creator>Pöpping, B.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7T5</scope><scope>7UA</scope><scope>C1K</scope><scope>F1W</scope><scope>H94</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20110218</creationdate><title>First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry</title><author>Heick, J. ; Fischer, M. ; Pöpping, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-ab32f8ef9bd853650d5bdabdbb45dc31774894473bf1c7b49aa18d243e4faf163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Allergen</topic><topic>Allergens - analysis</topic><topic>Allergens - chemistry</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Arachis hypogaea</topic><topic>Biological and medical sciences</topic><topic>Bread</topic><topic>Bread - analysis</topic><topic>Cereal and baking product industries</topic><topic>Chromatography, Liquid - methods</topic><topic>Corylus</topic><topic>Eggs - analysis</topic><topic>Food Analysis - methods</topic><topic>Food industries</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Immunopathology</topic><topic>Incurred reference material</topic><topic>Juglans</topic><topic>Liquid chromatography/tandem mass spectrometry</topic><topic>Medical sciences</topic><topic>Milk - chemistry</topic><topic>Molecular Sequence Data</topic><topic>Multi-method</topic><topic>Multiple reaction mode (MRM)</topic><topic>Nuts - chemistry</topic><topic>Peptides - analysis</topic><topic>Peptides - chemistry</topic><topic>Prunus dulcis</topic><topic>Soy Foods - analysis</topic><topic>Tandem Mass Spectrometry - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Heick, J.</creatorcontrib><creatorcontrib>Fischer, M.</creatorcontrib><creatorcontrib>Pöpping, B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Immunology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Journal of Chromatography A</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heick, J.</au><au>Fischer, M.</au><au>Pöpping, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry</atitle><jtitle>Journal of Chromatography A</jtitle><addtitle>J Chromatogr A</addtitle><date>2011-02-18</date><risdate>2011</risdate><volume>1218</volume><issue>7</issue><spage>938</spage><epage>943</epage><pages>938-943</pages><issn>0021-9673</issn><eissn>1873-3778</eissn><coden>JOCRAM</coden><abstract>The development of a multi-method for the detection of seven allergens based on liquid chromatography and triple-quadrupole tandem mass spectrometry in multiple reaction mode is described. It is based on extraction of the allergenic proteins from a food matrix, followed by enzymatic digestion with trypsin. The chosen marker peptides were implemented into one method that is capable of the simultaneous detection of milk, egg, soy, hazelnut, peanut, walnut and almond. This method has been used to detect all seven allergenic commodities from incurred reference bread material, which was baked according to a standard recipe from the baking industry. Detected concentrations ranged from 10 to 1000μg/g, demonstrating that the mass spectrometric based method is a useful tool for allergen screening.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>21227428</pmid><doi>10.1016/j.chroma.2010.12.067</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-9673 |
| ispartof | Journal of Chromatography A, 2011-02, Vol.1218 (7), p.938-943 |
| issn | 0021-9673 1873-3778 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1464503390 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Allergen Allergens - analysis Allergens - chemistry Amino Acid Sequence Animals Arachis hypogaea Biological and medical sciences Bread Bread - analysis Cereal and baking product industries Chromatography, Liquid - methods Corylus Eggs - analysis Food Analysis - methods Food industries Fundamental and applied biological sciences. Psychology General aspects Immunopathology Incurred reference material Juglans Liquid chromatography/tandem mass spectrometry Medical sciences Milk - chemistry Molecular Sequence Data Multi-method Multiple reaction mode (MRM) Nuts - chemistry Peptides - analysis Peptides - chemistry Prunus dulcis Soy Foods - analysis Tandem Mass Spectrometry - methods |
| title | First screening method for the simultaneous detection of seven allergens by liquid chromatography mass spectrometry |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T07%3A14%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=First%20screening%20method%20for%20the%20simultaneous%20detection%20of%20seven%20allergens%20by%20liquid%20chromatography%20mass%20spectrometry&rft.jtitle=Journal%20of%20Chromatography%20A&rft.au=Heick,%20J.&rft.date=2011-02-18&rft.volume=1218&rft.issue=7&rft.spage=938&rft.epage=943&rft.pages=938-943&rft.issn=0021-9673&rft.eissn=1873-3778&rft.coden=JOCRAM&rft_id=info:doi/10.1016/j.chroma.2010.12.067&rft_dat=%3Cproquest_cross%3E1464503390%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1464503390&rft_id=info:pmid/21227428&rft_els_id=S0021967310017619&rfr_iscdi=true |