Efficacy and Safety of Rabeprazole in Children (1–11 Years) With Gastroesophageal Reflux Disease

ABSTRACT Objective: Evaluate the efficacy and safety of rabeprazole in children, 1 to 11 years old, with endoscopically/histologically proven gastroesophageal reflux disease (GERD). Methods: Children were randomized to 0.5‐ or 1.0‐mg/kg rabeprazole granule formulation for 12 weeks. The dose was furt...

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Veröffentlicht in:	Journal of pediatric gastroenterology and nutrition 2013-12, Vol.57 (6), p.798-807
Hauptverfasser:	Haddad, Ibrahim, Kierkus, Jaroslaw, Tron, Eduardo, Ulmer, April, Hu, Peter, Sloan, Sheldon, Silber, Steven, Leitz, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Pain - drug therapy Abdominal Pain - etiology Biological and medical sciences Body Weight Child Child, Preschool Diarrhea - drug therapy Diarrhea - etiology Digestive system Dose-Response Relationship, Drug Esophagitis, Peptic - drug therapy Esophagitis, Peptic - etiology Esophagus Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - drug therapy Gastroesophageal Reflux - pathology gastroesophageal reflux disease Humans Infant Male Medical sciences Other diseases. Semiology pediatric Pharmacology. Drug treatments Proton Pump Inhibitors - administration & dosage Proton Pump Inhibitors - adverse effects Proton Pump Inhibitors - therapeutic use rabeprazole Rabeprazole - administration & dosage Rabeprazole - adverse effects Rabeprazole - therapeutic use Severity of Illness Index Treatment Outcome Vertebrates: anatomy and physiology, studies on body, several organs or systems Vomiting - drug therapy Vomiting - etiology
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