Combination of CK20 and Ki-67 Immunostaining Analysis Predicts Recurrence, Progression, and Cancer-Specific Survival in pT1 Urothelial Bladder Cancer

Abstract Background The prognostic value of CK20, Ki-67, and p53 has been investigated for non–muscle-invasive urothelial bladder cancers but not for the distinct and clinically challenging subset of pT1 bladder cancers. Objective To evaluate the prognostic value of CK20, Ki-67, and p53 within the l...

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Veröffentlicht in:	European urology 2014-01, Vol.65 (1), p.218-226
Hauptverfasser:	Bertz, Simone, Otto, Wolfgang, Denzinger, Stefan, Wieland, Wolf F, Burger, Maximilian, Stöhr, Robert, Link, Stefan, Hofstädter, Ferdinand, Hartmann, Arndt
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Transitional Cell - chemistry Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - mortality Carcinoma, Transitional Cell - pathology Disease Progression Female Humans Immunohistochemistry Keratin-20 - analysis Keratin-20 - biosynthesis Ki-67 Antigen - analysis Ki-67 Antigen - biosynthesis Male Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Recurrence, Local - mortality Neoplasm Staging Nephrology. Urinary tract diseases Predictive Value of Tests Prognosis pT1 bladder cancer Recurrence Retrospective Studies Risk assessment Survival Rate Tumors Tumors of the urinary system Urinary bladder carcinoma Urinary Bladder Neoplasms - chemistry Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology Urinary tract. Prostate gland Urology
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