Development of a short-term model of decalin inhalation nephrotoxicity in the male rat

Fischer 344 male rats and C57BL/6 male mice were exposed ‘continuously’ (22 hr/day, 7 days/wk) for 20, 28 or 35 days to a model compound, decalin, at 0, 25, 62.5 or 125 ppm. Fischer 344 female rats were exposed ‘continuously’ to decalin at 0 or 125 ppm for 28 days. No histopathological changes were...

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