19F/18F exchange synthesis for a novel [18F]S1P3-radiopharmaceutical

19F/18F isotope exchange is a useful method to label drug molecules containing 19F‐fluorine with 18F without modifying the drug molecule itself. Sphingosine‐1‐phosphate (S1P) is an important cellular mediator that functions by signaling through cell surface receptors. S1P is involved in several cell...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2013-06, Vol.56 (8), p.385-391
Hauptverfasser:	Rokka, Johanna, Federico, Cesare, Jurttila, Jori, Snellman, Anniina, Haaparanta, Merja, Rinne, Juha O., Solin, Olof
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorine Radioisotopes - chemistry Isotope Labeling Lysophospholipids - chemical synthesis nucleophilic 18F-fluorination PET chemistry radiolabelling Radiopharmaceuticals - chemical synthesis Receptors, Lysosphingolipid - metabolism S1P3 receptor Sphingosine - analogs & derivatives Sphingosine - chemical synthesis sphingosine-1-phosphate
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