Transplants of embryonic brainstem containing the locus coeruleus into spinal cord enhance the hindlimb flexion reflex in adult rats

Cell suspensions of embryonic brainstem containing the locus coeruleus were injected intervertebrally into the lumbar spinal cord of adult rats whose descending catecholamine (CA) fibers had been lesioned with intracisternal injection of 6-hydroxydopamine. Up to 1100 CA cells were found 2 and 4 mont...

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Veröffentlicht in:	Brain research 1986-09, Vol.381 (2), p.225-236
Hauptverfasser:	Buchanan, James T., Nornes, Howard O.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-hydroxydopamine Animals Biological and medical sciences brainstem catecholamine reinnervation Catecholamines - metabolism cell suspension Female Fundamental and applied biological sciences. Psychology General aspects. Models. Methods Hindlimb - innervation hindlimb flexion reflex Hydroxydopamines locus coeruleus Locus Coeruleus - transplantation lumbar spinal cord neural transplant Oxidopamine Rats Rats, Inbred Strains Reflex, Abnormal - therapy Spinal Cord - metabolism Spinal Cord Diseases - chemically induced Spinal Cord Diseases - metabolism Spinal Cord Diseases - therapy Vertebrates: nervous system and sense organs
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