A Dried Yeast Fermentate Selectively Modulates both the Luminal and Mucosal Gut Microbiota and Protects against Inflammation, As Studied in an Integrated in Vitro Approach

EpiCor, derived from Saccharomyces cerevisiae, has been shown to have immunomodulating properties in human clinical trials and in vitro. However, the underlying mechanisms behind its immune protection via the gut remain largely unknown. Therefore, the aim of this study was to use an integrated in vi...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2013-10, Vol.61 (39), p.9380-9392
Hauptverfasser:	Possemiers, Sam, Pinheiro, Iris, Verhelst, An, Van den Abbeele, Pieter, Maignien, Lois, Laukens, Debby, Reeves, Stuart G, Robinson, Larry E, Raas, Thomas, Schneider, Yves-Jacques, Van de Wiele, Tom, Marzorati, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion anti-inflammatory activity Anti-Inflammatory Agents - metabolism Bacterial Adhesion Bifidobacterium - growth & development Bifidobacterium - immunology Bifidobacterium - metabolism Biological and medical sciences Cell Line clinical trials Clostridium - growth & development Clostridium - immunology Clostridium - metabolism Coculture Techniques community structure cytokines Cytokines - antagonists & inhibitors Cytokines - metabolism digestive system Enterobacteriaceae - growth & development Enterobacteriaceae - immunology Enterobacteriaceae - metabolism Enterocytes - immunology Enterocytes - metabolism Enterocytes - microbiology Enterocytes - secretion Fermentation Food industries Fundamental and applied biological sciences. Psychology human cell lines Humans Immunologic Factors - metabolism immunomodulators inflammation intestinal microorganisms Lactobacillaceae - growth & development Lactobacillaceae - immunology Lactobacillaceae - metabolism Lactobacillus metabolism Monocytes - immunology Monocytes - metabolism Monocytes - microbiology Monocytes - secretion mucus Mucus - secretion pathogens Prebiotics Saccharomyces cerevisiae Saccharomyces cerevisiae - metabolism yeasts
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