Evaluation of the N Latex free light chain assay in the diagnosis and monitoring of AL amyloidosis

We compared a novel assay for free light chain (FLC) quantitation based on monoclonal antibodies (N-Latex, Siemens, Germany) to the established polyclonal antibody-based assay (Freelite , The Binding Site, UK) in AL amyloidosis. Sixty-two diagnostic samples were analysed on a BNII nephelometer, 32 o...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2013-12, Vol.51 (12), p.2303-2310
Hauptverfasser:	Mollee, Peter, Tate, Jill, Pretorius, Carel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AL amyloidosis Amyloidogenesis Amyloidosis Amyloidosis - blood Amyloidosis - diagnosis Amyloidosis - immunology Assaying Binding sites Chains Clinical Chemistry Tests diagnosis Diagnostic systems Electrophoresis free light chain assay Humans Immunoglobulin kappa-Chains - blood Immunoglobulin lambda-Chains - blood Latex Monitoring Monoclonal antibodies Quantitation Sensitivity Sensitivity and Specificity Survival Telemedicine
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