Utility of α -methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas

Summary The expression of α -methylacyl-coenzyme-A racemase (AMACR) has previously been reported in 75% to 100% of urethral/bladder clear cell carcinomas, tumors that are known to display broad phenotypic overlap with their identically named müllerian counterparts. Herein, we assess the utility of A...

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Veröffentlicht in:	Human pathology 2013-12, Vol.44 (12), p.2814-2821
Hauptverfasser:	Fadare, Oluwole, MD, Parkash, Vinita, MD, Gwin, Katja, MD, PhD, Hanley, Krisztina Z., MD, Jarboe,, Elke A., MD, Liang, Sharon X., MD, PhD, Quick, Charles M., MD, Zheng, Wenxin, MD, Rawish, Kojo R., MD, PhD, Hecht, Jonathan L., MD, PhD, Desouki, Mohamed M., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Clear Cell - diagnosis Adenocarcinoma, Clear Cell - metabolism Adenocarcinoma, Clear Cell - pathology Aged Aged, 80 and over Alpha-methylacyl-CoA-racemase AMACR Biomarkers, Tumor - metabolism Carcinoma, Endometrioid - diagnosis Carcinoma, Endometrioid - metabolism Carcinoma, Endometrioid - pathology Cystadenocarcinoma, Serous - diagnosis Cystadenocarcinoma, Serous - metabolism Cystadenocarcinoma, Serous - pathology Diagnosis, Differential Endometrial clear cell carcinoma Endometrial Neoplasms - diagnosis Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Female Humans Immunohistochemistry Lymphatic Metastasis - pathology Middle Aged p504s Pathology Racemases and Epimerases - metabolism
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