Efficacy and Safety of Angiotensin-Converting Enzyme Inhibitors in Patients With Left Ventricular Systolic Dysfunction and Hyponatremia

Abstract Background The presence of hyponatremia has been perceived to increase the risk of adverse events on initiation of treatment with angiotensin-converting enzyme inhibition in heart failure patients. The aim of this study was to investigate if baseline hyponatremia (plasma Na+

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Veröffentlicht in:	Journal of cardiac failure 2013-11, Vol.19 (11), p.725-730
Hauptverfasser:	Balling, Louise, MD, Kober, Lars, MD, DMSc, Schou, Morten, MD, PhD, Torp-Pedersen, Christian, MD, DMSc, Gustafsson, Finn, MD, PhD, DMSc
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE-I Aged Aged, 80 and over Angiotensin-Converting Enzyme Inhibitors - adverse effects Angiotensin-Converting Enzyme Inhibitors - therapeutic use Cardiovascular Double-Blind Method Female Follow-Up Studies heart failure Humans hyponatremia Hyponatremia - drug therapy Hyponatremia - mortality Hypotension - chemically induced Hypotension - diagnosis Indoles - adverse effects Indoles - therapeutic use Male Middle Aged Prospective Studies Retrospective Studies Survival Rate - trends Treatment Outcome Ventricular Dysfunction, Left - drug therapy Ventricular Dysfunction, Left - mortality
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Zusammenfassung:	Abstract Background The presence of hyponatremia has been perceived to increase the risk of adverse events on initiation of treatment with angiotensin-converting enzyme inhibition in heart failure patients. The aim of this study was to investigate if baseline hyponatremia (plasma Na+
ISSN:	1071-9164 1532-8414
DOI:	10.1016/j.cardfail.2013.09.004