Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema
Purpose Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized, as current reports of its clinical features show. To determine CPFE’s physiologic and radiologic features, we conducted quantitative assessment of computed tomography scans to compare with those of chronic obstructi...
Gespeichert in:
| Veröffentlicht in: | Lung 2013-12, Vol.191 (6), p.585-591 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 591 |
|---|---|
| container_issue | 6 |
| container_start_page | 585 |
| container_title | Lung |
| container_volume | 191 |
| creator | Ando, Katsutoshi Sekiya, Mitsuaki Tobino, Kazunori Takahashi, Kazuhisa |
| description | Purpose
Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized, as current reports of its clinical features show. To determine CPFE’s physiologic and radiologic features, we conducted quantitative assessment of computed tomography scans to compare with those of chronic obstructive pulmonary disease (COPD).
Methods
In 23 patients with CPFE and 42 patients with COPD, we measured the extent of emphysema (LAA %), parenchymal density, and total cross-sectional areas of pulmonary vessels smaller than 5 mm
2
(%CSA |
| doi_str_mv | 10.1007/s00408-013-9513-1 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1461337334</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A433047462</galeid><sourcerecordid>A433047462</sourcerecordid><originalsourceid>FETCH-LOGICAL-c710t-1cd876116550acfa537486da9dde3b11d83438618a6080288f33a76261fc13943</originalsourceid><addsrcrecordid>eNqNkl2L1DAUhoMo7jj6A7yRgiDedM3pST_mch12VVjxg_U6ZNLTmSxtMiatsv_e1K7SkXFZAgnkPO97DsnL2HPgp8B5-SZwLniVcsB0lccNHrAFCMxSKHP-kC04CkizyJywJyFccw5lAfljdpJFWY4ZX7D9V2pVb5wNO7NP3lL_k8gmXwZle9PHwg9K1lfJR-q90SFRtk4-D23nrPI3ycVg9ShNjE3WrtsYSwdls_EumEl13u13N4E69ZQ9alQb6NntuWTfLs6v1u_Ty0_vPqzPLlNdAu9T0HUVh4Uiz7nSjcqxFFVRq1VdE24A6goFVgVUquAVz6qqQVRlkRXQaMCVwCV7Pfnuvfs-UOhlZ4KmtlWW3BAkiAIQS8QRffkPeu0Gb-N0I8UFIMyprWpJGtu43is9msozgchFKYrsTgrjk0OG0W3J0iPUlix51TpLjYnXB6734ef-p0f4uGrqjD7a4F6CeYdXM8GOVNvvgmuH31E6dL4TnDvCBOqYmuCpkXtvuhgkCVyOcZdT3GWMuxzjLkfNi9ufGzYd1X8Vf_IdgWwCQizZLfnZ1_7X9RcqBgL4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1460413134</pqid></control><display><type>article</type><title>Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Ando, Katsutoshi ; Sekiya, Mitsuaki ; Tobino, Kazunori ; Takahashi, Kazuhisa</creator><creatorcontrib>Ando, Katsutoshi ; Sekiya, Mitsuaki ; Tobino, Kazunori ; Takahashi, Kazuhisa</creatorcontrib><description>Purpose
Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized, as current reports of its clinical features show. To determine CPFE’s physiologic and radiologic features, we conducted quantitative assessment of computed tomography scans to compare with those of chronic obstructive pulmonary disease (COPD).
Methods
In 23 patients with CPFE and 42 patients with COPD, we measured the extent of emphysema (LAA %), parenchymal density, and total cross-sectional areas of pulmonary vessels smaller than 5 mm
2
(%CSA <5) and 5–10 mm
2
(%CSA 5–10).
Results
For CPFE, airflow was better, but diffusing capacity for carbon monoxide (DL
CO
) was worse than for COPD, whereas LAA % was similar for both groups. The %CSA <5 was greater but %CSA5–10 was less in CPFE than COPD. COPD involved a negative correlation between DL
CO
and LAA % at all lung sites; those factors correlated for CPFE only in the upper lobe (
r
= −0.535). In contrast, CPFE had a negative correlation between DL
CO
and parenchymal density in lower lobes (
r
= −0.453), but COPD showed no correlation in any such sections. In CPFE, no correlation was apparent between LAA in upper lobes and parenchymal density in lower lobes. The annual rate of FVC decline (−169.26 ml/year) in CPFE patients correlated with parenchymal density (
r
= −0.714).
Conclusions
In CPFE, fibrosis and emphysema apparently existed independently, but both correlate with and likely contribute to the disproportionate reduction in gas exchange. Our study also suggested that pulmonary fibrotic changes may be more important contributors than emphysema for disease progression.</description><identifier>ISSN: 0341-2040</identifier><identifier>EISSN: 1432-1750</identifier><identifier>DOI: 10.1007/s00408-013-9513-1</identifier><identifier>PMID: 24085320</identifier><identifier>CODEN: LUNGD9</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aged ; Care and treatment ; Chronic obstructive pulmonary disease ; CT imaging ; Development and progression ; Diagnosis ; Disease Progression ; Emphysema ; Emphysema, Pulmonary ; Female ; Forced Expiratory Volume ; Humans ; Lung - diagnostic imaging ; Lung - physiopathology ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multidetector Computed Tomography ; Pneumology/Respiratory System ; Predictive Value of Tests ; Prognosis ; Pulmonary Diffusing Capacity ; Pulmonary Disease, Chronic Obstructive - diagnosis ; Pulmonary Disease, Chronic Obstructive - diagnostic imaging ; Pulmonary Disease, Chronic Obstructive - physiopathology ; Pulmonary Emphysema - complications ; Pulmonary Emphysema - diagnosis ; Pulmonary Emphysema - diagnostic imaging ; Pulmonary Emphysema - physiopathology ; Pulmonary fibrosis ; Pulmonary Fibrosis - complications ; Pulmonary Fibrosis - diagnosis ; Pulmonary Fibrosis - diagnostic imaging ; Pulmonary Fibrosis - physiopathology ; Respiratory Function Tests ; Retrospective Studies ; Risk factors ; Severity of Illness Index ; Tomography ; Vital Capacity</subject><ispartof>Lung, 2013-12, Vol.191 (6), p.585-591</ispartof><rights>Springer Science+Business Media New York 2013</rights><rights>COPYRIGHT 2013 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c710t-1cd876116550acfa537486da9dde3b11d83438618a6080288f33a76261fc13943</citedby><cites>FETCH-LOGICAL-c710t-1cd876116550acfa537486da9dde3b11d83438618a6080288f33a76261fc13943</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00408-013-9513-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00408-013-9513-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24085320$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ando, Katsutoshi</creatorcontrib><creatorcontrib>Sekiya, Mitsuaki</creatorcontrib><creatorcontrib>Tobino, Kazunori</creatorcontrib><creatorcontrib>Takahashi, Kazuhisa</creatorcontrib><title>Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema</title><title>Lung</title><addtitle>Lung</addtitle><addtitle>Lung</addtitle><description>Purpose
Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized, as current reports of its clinical features show. To determine CPFE’s physiologic and radiologic features, we conducted quantitative assessment of computed tomography scans to compare with those of chronic obstructive pulmonary disease (COPD).
Methods
In 23 patients with CPFE and 42 patients with COPD, we measured the extent of emphysema (LAA %), parenchymal density, and total cross-sectional areas of pulmonary vessels smaller than 5 mm
2
(%CSA <5) and 5–10 mm
2
(%CSA 5–10).
Results
For CPFE, airflow was better, but diffusing capacity for carbon monoxide (DL
CO
) was worse than for COPD, whereas LAA % was similar for both groups. The %CSA <5 was greater but %CSA5–10 was less in CPFE than COPD. COPD involved a negative correlation between DL
CO
and LAA % at all lung sites; those factors correlated for CPFE only in the upper lobe (
r
= −0.535). In contrast, CPFE had a negative correlation between DL
CO
and parenchymal density in lower lobes (
r
= −0.453), but COPD showed no correlation in any such sections. In CPFE, no correlation was apparent between LAA in upper lobes and parenchymal density in lower lobes. The annual rate of FVC decline (−169.26 ml/year) in CPFE patients correlated with parenchymal density (
r
= −0.714).
Conclusions
In CPFE, fibrosis and emphysema apparently existed independently, but both correlate with and likely contribute to the disproportionate reduction in gas exchange. Our study also suggested that pulmonary fibrotic changes may be more important contributors than emphysema for disease progression.</description><subject>Aged</subject><subject>Care and treatment</subject><subject>Chronic obstructive pulmonary disease</subject><subject>CT imaging</subject><subject>Development and progression</subject><subject>Diagnosis</subject><subject>Disease Progression</subject><subject>Emphysema</subject><subject>Emphysema, Pulmonary</subject><subject>Female</subject><subject>Forced Expiratory Volume</subject><subject>Humans</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - physiopathology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multidetector Computed Tomography</subject><subject>Pneumology/Respiratory System</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Pulmonary Diffusing Capacity</subject><subject>Pulmonary Disease, Chronic Obstructive - diagnosis</subject><subject>Pulmonary Disease, Chronic Obstructive - diagnostic imaging</subject><subject>Pulmonary Disease, Chronic Obstructive - physiopathology</subject><subject>Pulmonary Emphysema - complications</subject><subject>Pulmonary Emphysema - diagnosis</subject><subject>Pulmonary Emphysema - diagnostic imaging</subject><subject>Pulmonary Emphysema - physiopathology</subject><subject>Pulmonary fibrosis</subject><subject>Pulmonary Fibrosis - complications</subject><subject>Pulmonary Fibrosis - diagnosis</subject><subject>Pulmonary Fibrosis - diagnostic imaging</subject><subject>Pulmonary Fibrosis - physiopathology</subject><subject>Respiratory Function Tests</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Severity of Illness Index</subject><subject>Tomography</subject><subject>Vital Capacity</subject><issn>0341-2040</issn><issn>1432-1750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkl2L1DAUhoMo7jj6A7yRgiDedM3pST_mch12VVjxg_U6ZNLTmSxtMiatsv_e1K7SkXFZAgnkPO97DsnL2HPgp8B5-SZwLniVcsB0lccNHrAFCMxSKHP-kC04CkizyJywJyFccw5lAfljdpJFWY4ZX7D9V2pVb5wNO7NP3lL_k8gmXwZle9PHwg9K1lfJR-q90SFRtk4-D23nrPI3ycVg9ShNjE3WrtsYSwdls_EumEl13u13N4E69ZQ9alQb6NntuWTfLs6v1u_Ty0_vPqzPLlNdAu9T0HUVh4Uiz7nSjcqxFFVRq1VdE24A6goFVgVUquAVz6qqQVRlkRXQaMCVwCV7Pfnuvfs-UOhlZ4KmtlWW3BAkiAIQS8QRffkPeu0Gb-N0I8UFIMyprWpJGtu43is9msozgchFKYrsTgrjk0OG0W3J0iPUlix51TpLjYnXB6734ef-p0f4uGrqjD7a4F6CeYdXM8GOVNvvgmuH31E6dL4TnDvCBOqYmuCpkXtvuhgkCVyOcZdT3GWMuxzjLkfNi9ufGzYd1X8Vf_IdgWwCQizZLfnZ1_7X9RcqBgL4</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Ando, Katsutoshi</creator><creator>Sekiya, Mitsuaki</creator><creator>Tobino, Kazunori</creator><creator>Takahashi, Kazuhisa</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20131201</creationdate><title>Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema</title><author>Ando, Katsutoshi ; Sekiya, Mitsuaki ; Tobino, Kazunori ; Takahashi, Kazuhisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c710t-1cd876116550acfa537486da9dde3b11d83438618a6080288f33a76261fc13943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Care and treatment</topic><topic>Chronic obstructive pulmonary disease</topic><topic>CT imaging</topic><topic>Development and progression</topic><topic>Diagnosis</topic><topic>Disease Progression</topic><topic>Emphysema</topic><topic>Emphysema, Pulmonary</topic><topic>Female</topic><topic>Forced Expiratory Volume</topic><topic>Humans</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - physiopathology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multidetector Computed Tomography</topic><topic>Pneumology/Respiratory System</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Pulmonary Diffusing Capacity</topic><topic>Pulmonary Disease, Chronic Obstructive - diagnosis</topic><topic>Pulmonary Disease, Chronic Obstructive - diagnostic imaging</topic><topic>Pulmonary Disease, Chronic Obstructive - physiopathology</topic><topic>Pulmonary Emphysema - complications</topic><topic>Pulmonary Emphysema - diagnosis</topic><topic>Pulmonary Emphysema - diagnostic imaging</topic><topic>Pulmonary Emphysema - physiopathology</topic><topic>Pulmonary fibrosis</topic><topic>Pulmonary Fibrosis - complications</topic><topic>Pulmonary Fibrosis - diagnosis</topic><topic>Pulmonary Fibrosis - diagnostic imaging</topic><topic>Pulmonary Fibrosis - physiopathology</topic><topic>Respiratory Function Tests</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Severity of Illness Index</topic><topic>Tomography</topic><topic>Vital Capacity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ando, Katsutoshi</creatorcontrib><creatorcontrib>Sekiya, Mitsuaki</creatorcontrib><creatorcontrib>Tobino, Kazunori</creatorcontrib><creatorcontrib>Takahashi, Kazuhisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Lung</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ando, Katsutoshi</au><au>Sekiya, Mitsuaki</au><au>Tobino, Kazunori</au><au>Takahashi, Kazuhisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema</atitle><jtitle>Lung</jtitle><stitle>Lung</stitle><addtitle>Lung</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>191</volume><issue>6</issue><spage>585</spage><epage>591</epage><pages>585-591</pages><issn>0341-2040</issn><eissn>1432-1750</eissn><coden>LUNGD9</coden><abstract>Purpose
Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized, as current reports of its clinical features show. To determine CPFE’s physiologic and radiologic features, we conducted quantitative assessment of computed tomography scans to compare with those of chronic obstructive pulmonary disease (COPD).
Methods
In 23 patients with CPFE and 42 patients with COPD, we measured the extent of emphysema (LAA %), parenchymal density, and total cross-sectional areas of pulmonary vessels smaller than 5 mm
2
(%CSA <5) and 5–10 mm
2
(%CSA 5–10).
Results
For CPFE, airflow was better, but diffusing capacity for carbon monoxide (DL
CO
) was worse than for COPD, whereas LAA % was similar for both groups. The %CSA <5 was greater but %CSA5–10 was less in CPFE than COPD. COPD involved a negative correlation between DL
CO
and LAA % at all lung sites; those factors correlated for CPFE only in the upper lobe (
r
= −0.535). In contrast, CPFE had a negative correlation between DL
CO
and parenchymal density in lower lobes (
r
= −0.453), but COPD showed no correlation in any such sections. In CPFE, no correlation was apparent between LAA in upper lobes and parenchymal density in lower lobes. The annual rate of FVC decline (−169.26 ml/year) in CPFE patients correlated with parenchymal density (
r
= −0.714).
Conclusions
In CPFE, fibrosis and emphysema apparently existed independently, but both correlate with and likely contribute to the disproportionate reduction in gas exchange. Our study also suggested that pulmonary fibrotic changes may be more important contributors than emphysema for disease progression.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>24085320</pmid><doi>10.1007/s00408-013-9513-1</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0341-2040 |
| ispartof | Lung, 2013-12, Vol.191 (6), p.585-591 |
| issn | 0341-2040 1432-1750 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1461337334 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Aged Care and treatment Chronic obstructive pulmonary disease CT imaging Development and progression Diagnosis Disease Progression Emphysema Emphysema, Pulmonary Female Forced Expiratory Volume Humans Lung - diagnostic imaging Lung - physiopathology Male Medicine Medicine & Public Health Middle Aged Multidetector Computed Tomography Pneumology/Respiratory System Predictive Value of Tests Prognosis Pulmonary Diffusing Capacity Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - diagnostic imaging Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary Emphysema - complications Pulmonary Emphysema - diagnosis Pulmonary Emphysema - diagnostic imaging Pulmonary Emphysema - physiopathology Pulmonary fibrosis Pulmonary Fibrosis - complications Pulmonary Fibrosis - diagnosis Pulmonary Fibrosis - diagnostic imaging Pulmonary Fibrosis - physiopathology Respiratory Function Tests Retrospective Studies Risk factors Severity of Illness Index Tomography Vital Capacity |
| title | Relationship Between Quantitative CT Metrics and Pulmonary Function in Combined Pulmonary Fibrosis and Emphysema |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T05%3A10%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relationship%20Between%20Quantitative%20CT%20Metrics%20and%20Pulmonary%20Function%20in%20Combined%20Pulmonary%20Fibrosis%20and%20Emphysema&rft.jtitle=Lung&rft.au=Ando,%20Katsutoshi&rft.date=2013-12-01&rft.volume=191&rft.issue=6&rft.spage=585&rft.epage=591&rft.pages=585-591&rft.issn=0341-2040&rft.eissn=1432-1750&rft.coden=LUNGD9&rft_id=info:doi/10.1007/s00408-013-9513-1&rft_dat=%3Cgale_proqu%3EA433047462%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1460413134&rft_id=info:pmid/24085320&rft_galeid=A433047462&rfr_iscdi=true |