Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass

Abstract Objectives The aim of this study was to examine the effects of 45S5 bioactive glass (BAG) on the acid neutralizing, mechanical and physical properties of pit and fissure sealants. Methods 45S5BAG ( 0.05), except for BAG50. Significance The novel pit and fissure sealants neutralized the acid...

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Veröffentlicht in:Dental materials 2013-12, Vol.29 (12), p.1228-1235
Hauptverfasser: Yang, Song-Yi, Piao, Yin-Zhu, Kim, Sung-Min, Lee, Yong-Keun, Kim, Kyoung-Nam, Kim, Kwang-Mahn
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container_end_page 1235
container_issue 12
container_start_page 1228
container_title Dental materials
container_volume 29
creator Yang, Song-Yi
Piao, Yin-Zhu
Kim, Sung-Min
Lee, Yong-Keun
Kim, Kyoung-Nam
Kim, Kwang-Mahn
description Abstract Objectives The aim of this study was to examine the effects of 45S5 bioactive glass (BAG) on the acid neutralizing, mechanical and physical properties of pit and fissure sealants. Methods 45S5BAG ( 0.05), except for BAG50. Significance The novel pit and fissure sealants neutralized the acid solution (pH 4.0) and exhibited appropriate mechanical and physical properties. Therefore, these compounds are suitable candidates for caries-inhibiting dental materials.
doi_str_mv 10.1016/j.dental.2013.09.007
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Methods 45S5BAG (&lt;25 μm) was mixed with the silanized glass (180 ± 30 nm) and added into a resin matrix [Bis-GMA/TEGDMA 50/50 (wt%) containing 1% of DMAEMA/CQ 2:1 (wt%)] with varying filler proportions; 0% 45S5BAG + 50% glass (BAG0); 12.5% 45S5BAG + 37.5% glass (BAG12.5); 25% 45S5BAG + 25% glass (BAG25); 37.5% 45S5BAG + 12.5% glass (BAG37.5); and 50% 45S5BAG + 0% glass (BAG50). To evaluate the acid neutralizing properties, specimens were immersed in lactic acid solution (pH 4.0). Then, the change in pH and the time required to raise the pH from 4.0 to 5.5 were measured. In addition, flexural strength, water sorption and solubility were analyzed. Results The acid neutralizing properties of each group exhibited increasing pH values as more 45S5BAG was added, and the time required to raise the pH from 4.0 to 5.5 became shorter as the proportion of 45S5BAG increased ( P &lt; 0.05). Additionally, the flexural strength decreased according to the increasing proportions of 45S5BAG added ( P &lt; 0.05). Water sorption showed an increasing trend with increasing proportions of 45S5 BAG added ( P &lt; 0.05). However, the solubility results were similar among the groups ( P &gt; 0.05), except for BAG50. Significance The novel pit and fissure sealants neutralized the acid solution (pH 4.0) and exhibited appropriate mechanical and physical properties. Therefore, these compounds are suitable candidates for caries-inhibiting dental materials.</description><identifier>ISSN: 0109-5641</identifier><identifier>EISSN: 1879-0097</identifier><identifier>DOI: 10.1016/j.dental.2013.09.007</identifier><identifier>PMID: 24139755</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>45S5 bioactive glass ; Acid neutralizing property ; Acids - chemistry ; Advanced Basic Science ; Ceramics ; Dentistry ; Glass ; Materials Testing ; Mechanical property ; Physical property ; Pit and fissure sealant ; Pit and Fissure Sealants ; Solubility ; Water - chemistry</subject><ispartof>Dental materials, 2013-12, Vol.29 (12), p.1228-1235</ispartof><rights>Academy of Dental Materials</rights><rights>2013 Academy of Dental Materials</rights><rights>Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-8dfd8d7d035016767ffaed4cd2ac081bf0ffad6ea0dc60c4e50ea213362cc7313</citedby><cites>FETCH-LOGICAL-c483t-8dfd8d7d035016767ffaed4cd2ac081bf0ffad6ea0dc60c4e50ea213362cc7313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.dental.2013.09.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24139755$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Song-Yi</creatorcontrib><creatorcontrib>Piao, Yin-Zhu</creatorcontrib><creatorcontrib>Kim, Sung-Min</creatorcontrib><creatorcontrib>Lee, Yong-Keun</creatorcontrib><creatorcontrib>Kim, Kyoung-Nam</creatorcontrib><creatorcontrib>Kim, Kwang-Mahn</creatorcontrib><title>Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass</title><title>Dental materials</title><addtitle>Dent Mater</addtitle><description>Abstract Objectives The aim of this study was to examine the effects of 45S5 bioactive glass (BAG) on the acid neutralizing, mechanical and physical properties of pit and fissure sealants. Methods 45S5BAG (&lt;25 μm) was mixed with the silanized glass (180 ± 30 nm) and added into a resin matrix [Bis-GMA/TEGDMA 50/50 (wt%) containing 1% of DMAEMA/CQ 2:1 (wt%)] with varying filler proportions; 0% 45S5BAG + 50% glass (BAG0); 12.5% 45S5BAG + 37.5% glass (BAG12.5); 25% 45S5BAG + 25% glass (BAG25); 37.5% 45S5BAG + 12.5% glass (BAG37.5); and 50% 45S5BAG + 0% glass (BAG50). To evaluate the acid neutralizing properties, specimens were immersed in lactic acid solution (pH 4.0). Then, the change in pH and the time required to raise the pH from 4.0 to 5.5 were measured. In addition, flexural strength, water sorption and solubility were analyzed. Results The acid neutralizing properties of each group exhibited increasing pH values as more 45S5BAG was added, and the time required to raise the pH from 4.0 to 5.5 became shorter as the proportion of 45S5BAG increased ( P &lt; 0.05). Additionally, the flexural strength decreased according to the increasing proportions of 45S5BAG added ( P &lt; 0.05). Water sorption showed an increasing trend with increasing proportions of 45S5 BAG added ( P &lt; 0.05). However, the solubility results were similar among the groups ( P &gt; 0.05), except for BAG50. Significance The novel pit and fissure sealants neutralized the acid solution (pH 4.0) and exhibited appropriate mechanical and physical properties. Therefore, these compounds are suitable candidates for caries-inhibiting dental materials.</description><subject>45S5 bioactive glass</subject><subject>Acid neutralizing property</subject><subject>Acids - chemistry</subject><subject>Advanced Basic Science</subject><subject>Ceramics</subject><subject>Dentistry</subject><subject>Glass</subject><subject>Materials Testing</subject><subject>Mechanical property</subject><subject>Physical property</subject><subject>Pit and fissure sealant</subject><subject>Pit and Fissure Sealants</subject><subject>Solubility</subject><subject>Water - chemistry</subject><issn>0109-5641</issn><issn>1879-0097</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUcFu1DAQtRCIbgt_gJCPHEgYx06cXJCqCihSpR7ani2vPWm9ZJPgcSotB74d727hwKUnazxv3sx7j7F3AkoBovm0KT2OyQ5lBUKW0JUA-gVbiVZ3BUCnX7IVCOiKulHihJ0SbQBAVZ14zU4qJWSn63rFfp-74PmIS4p2CL_CeP-Rb9E92DE4O3A7ej4_7OhQzHGaMaaAxKeezyEd2n0gWiJyQjvYMRF3Uz4rjJkqMw2p8BjDI3qu6puar8NkXco1vx8s0Rv2qrcD4dun94zdff1ye3FZXF1_-35xflU41cpUtL73rdceZJ2l60b3vUWvnK-sg1ase8gfvkEL3jXgFNaAthJSNpVzWgp5xj4cebOGnwtSMttADod8MU4LGaHqrm4qrSBD1RHq4kQUsTdzDFsbd0aA2TtvNubovNk7b6Az2fk89v5pw7Leov839NfqDPh8BGDW-RgwGnIBR4c-RHTJ-Ck8t-F_AjeEQ0w_cIe0mZY4Zg-NMFQZMDf79PfhC5lzl62WfwDB1a3p</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Yang, Song-Yi</creator><creator>Piao, Yin-Zhu</creator><creator>Kim, Sung-Min</creator><creator>Lee, Yong-Keun</creator><creator>Kim, Kyoung-Nam</creator><creator>Kim, Kwang-Mahn</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20131201</creationdate><title>Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass</title><author>Yang, Song-Yi ; Piao, Yin-Zhu ; Kim, Sung-Min ; Lee, Yong-Keun ; Kim, Kyoung-Nam ; Kim, Kwang-Mahn</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-8dfd8d7d035016767ffaed4cd2ac081bf0ffad6ea0dc60c4e50ea213362cc7313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>45S5 bioactive glass</topic><topic>Acid neutralizing property</topic><topic>Acids - chemistry</topic><topic>Advanced Basic Science</topic><topic>Ceramics</topic><topic>Dentistry</topic><topic>Glass</topic><topic>Materials Testing</topic><topic>Mechanical property</topic><topic>Physical property</topic><topic>Pit and fissure sealant</topic><topic>Pit and Fissure Sealants</topic><topic>Solubility</topic><topic>Water - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Song-Yi</creatorcontrib><creatorcontrib>Piao, Yin-Zhu</creatorcontrib><creatorcontrib>Kim, Sung-Min</creatorcontrib><creatorcontrib>Lee, Yong-Keun</creatorcontrib><creatorcontrib>Kim, Kyoung-Nam</creatorcontrib><creatorcontrib>Kim, Kwang-Mahn</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dental materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Song-Yi</au><au>Piao, Yin-Zhu</au><au>Kim, Sung-Min</au><au>Lee, Yong-Keun</au><au>Kim, Kyoung-Nam</au><au>Kim, Kwang-Mahn</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass</atitle><jtitle>Dental materials</jtitle><addtitle>Dent Mater</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>29</volume><issue>12</issue><spage>1228</spage><epage>1235</epage><pages>1228-1235</pages><issn>0109-5641</issn><eissn>1879-0097</eissn><abstract>Abstract Objectives The aim of this study was to examine the effects of 45S5 bioactive glass (BAG) on the acid neutralizing, mechanical and physical properties of pit and fissure sealants. Methods 45S5BAG (&lt;25 μm) was mixed with the silanized glass (180 ± 30 nm) and added into a resin matrix [Bis-GMA/TEGDMA 50/50 (wt%) containing 1% of DMAEMA/CQ 2:1 (wt%)] with varying filler proportions; 0% 45S5BAG + 50% glass (BAG0); 12.5% 45S5BAG + 37.5% glass (BAG12.5); 25% 45S5BAG + 25% glass (BAG25); 37.5% 45S5BAG + 12.5% glass (BAG37.5); and 50% 45S5BAG + 0% glass (BAG50). To evaluate the acid neutralizing properties, specimens were immersed in lactic acid solution (pH 4.0). Then, the change in pH and the time required to raise the pH from 4.0 to 5.5 were measured. In addition, flexural strength, water sorption and solubility were analyzed. Results The acid neutralizing properties of each group exhibited increasing pH values as more 45S5BAG was added, and the time required to raise the pH from 4.0 to 5.5 became shorter as the proportion of 45S5BAG increased ( P &lt; 0.05). Additionally, the flexural strength decreased according to the increasing proportions of 45S5BAG added ( P &lt; 0.05). Water sorption showed an increasing trend with increasing proportions of 45S5 BAG added ( P &lt; 0.05). However, the solubility results were similar among the groups ( P &gt; 0.05), except for BAG50. Significance The novel pit and fissure sealants neutralized the acid solution (pH 4.0) and exhibited appropriate mechanical and physical properties. Therefore, these compounds are suitable candidates for caries-inhibiting dental materials.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>24139755</pmid><doi>10.1016/j.dental.2013.09.007</doi><tpages>8</tpages></addata></record>
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subjects 45S5 bioactive glass
Acid neutralizing property
Acids - chemistry
Advanced Basic Science
Ceramics
Dentistry
Glass
Materials Testing
Mechanical property
Physical property
Pit and fissure sealant
Pit and Fissure Sealants
Solubility
Water - chemistry
title Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass
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