PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis

The mouse protein phosphatase gene Ppp1cc is essential for male fertility, with mutants displaying a failure in spermatogenesis including a widespread loss of post-meiotic germ cells and abnormalities in the mitochondrial sheath. This phenotype is hypothesized to be responsible for the loss of the t...

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Veröffentlicht in:	Reproduction (Cambridge, England) England), 2014-01, Vol.147 (1), p.1-12
Hauptverfasser:	MacLeod, Graham, Shang, Peng, Booth, Gregory T, Mastropaolo, Lucas A, Manafpoursakha, Niloufar, Vogl, A Wayne, Varmuza, Susannah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Male Mice Mice, Knockout Phosphoproteins - genetics Phosphoproteins - metabolism Phosphorylation Protein Phosphatase 1 - genetics Protein Phosphatase 1 - metabolism Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Spermatogenesis - physiology Testis - metabolism
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