Chemical and toxicological evaluation of transformation products during advanced oxidation processes
The entry of pharmaceuticals into the water cycle from sewage treatment plants is of growing concern because environmental effects are evident at trace levels. Ozonation, UV- and UV/H(2)O(2)-treatment were tested as an additional step in waste water treatment because they have been proven to be effe...
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Veröffentlicht in: | Water science and technology 2013-01, Vol.68 (9), p.1976-1983 |
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container_end_page | 1983 |
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container_issue | 9 |
container_start_page | 1976 |
container_title | Water science and technology |
container_volume | 68 |
creator | VOM EYSER, C BÖRGERS, A RICHARD, J DOPP, E JANZEN, N BESTER, K TUERK, J |
description | The entry of pharmaceuticals into the water cycle from sewage treatment plants is of growing concern because environmental effects are evident at trace levels. Ozonation, UV- and UV/H(2)O(2)-treatment were tested as an additional step in waste water treatment because they have been proven to be effective in eliminating aqueous organic contaminants. The pharmaceuticals carbamazepine, ciprofloxacin, diclofenac, metoprolol and sulfamethoxazole as well as the personal care products galaxolide and tonalide were investigated in terms of degradation efficiency and by-product formation in consideration of toxic effects. The substances were largely removed from treatment plant effluent by ozonation, UV- and UV/H(2)O(2)-treatment. Transformation products were detected in all tested treatment processes. Accompanying analysis showed no genotoxic, cytotoxic or estrogenic potential for the investigated compounds after oxidative treatment of real waste waters. The results indicate that by-product formation from ozonation and advanced oxidation processes does not have any negative environmental impact. |
doi_str_mv | 10.2166/wst.2013.452 |
format | Article |
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Ozonation, UV- and UV/H(2)O(2)-treatment were tested as an additional step in waste water treatment because they have been proven to be effective in eliminating aqueous organic contaminants. The pharmaceuticals carbamazepine, ciprofloxacin, diclofenac, metoprolol and sulfamethoxazole as well as the personal care products galaxolide and tonalide were investigated in terms of degradation efficiency and by-product formation in consideration of toxic effects. The substances were largely removed from treatment plant effluent by ozonation, UV- and UV/H(2)O(2)-treatment. Transformation products were detected in all tested treatment processes. Accompanying analysis showed no genotoxic, cytotoxic or estrogenic potential for the investigated compounds after oxidative treatment of real waste waters. The results indicate that by-product formation from ozonation and advanced oxidation processes does not have any negative environmental impact.</description><identifier>ISSN: 0273-1223</identifier><identifier>EISSN: 1996-9732</identifier><identifier>DOI: 10.2166/wst.2013.452</identifier><identifier>PMID: 24225097</identifier><identifier>CODEN: WSTED4</identifier><language>eng</language><publisher>London: International Water Association</publisher><subject>Animals ; Applied sciences ; Biodegradation ; Biological and medical sciences ; Byproducts ; Carbamazepine ; Chemical wastewater ; Chromatography, High Pressure Liquid ; Ciprofloxacin ; Consumer products ; Contaminants ; Cytotoxicity ; Diclofenac ; Drugs ; Environmental effects ; Environmental impact ; Environmental Monitoring ; Environmental pollutants toxicology ; Evaluation ; Exact sciences and technology ; Gas Chromatography-Mass Spectrometry ; General purification processes ; Genotoxicity ; Hydrogen peroxide ; Hydrogen Peroxide - chemistry ; Hydrologic cycle ; Hydrological cycle ; Medical sciences ; Metoprolol ; Organic contaminants ; Oxidation ; Oxidation-Reduction ; Ozonation ; Ozone - chemistry ; Ozonization ; Pharmaceutical Preparations - analysis ; Pharmaceutical Preparations - metabolism ; Pharmaceuticals ; Pollution ; Products ; Sewage ; Sewage treatment ; Sewage treatment plants ; Sulfamethoxazole ; Tonalide ; Toxicity Tests ; Toxicology ; Trace levels ; Ultraviolet radiation ; Waste Disposal, Fluid - methods ; Waste Water - analysis ; Waste Water - chemistry ; Wastewater ; Wastewater treatment ; Wastewater treatment plants ; Wastewaters ; Water ; Water Pollutants, Chemical - analysis ; Water Pollutants, Chemical - toxicity ; Water treatment ; Water treatment and pollution ; Xenoestrogens</subject><ispartof>Water science and technology, 2013-01, Vol.68 (9), p.1976-1983</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright IWA Publishing Nov 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-83ee63d38ba3d7aea442fb03c48cd6f894dab0cea383803f432684c0969ef0e73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28200212$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24225097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VOM EYSER, C</creatorcontrib><creatorcontrib>BÖRGERS, A</creatorcontrib><creatorcontrib>RICHARD, J</creatorcontrib><creatorcontrib>DOPP, E</creatorcontrib><creatorcontrib>JANZEN, N</creatorcontrib><creatorcontrib>BESTER, K</creatorcontrib><creatorcontrib>TUERK, J</creatorcontrib><title>Chemical and toxicological evaluation of transformation products during advanced oxidation processes</title><title>Water science and technology</title><addtitle>Water Sci Technol</addtitle><description>The entry of pharmaceuticals into the water cycle from sewage treatment plants is of growing concern because environmental effects are evident at trace levels. Ozonation, UV- and UV/H(2)O(2)-treatment were tested as an additional step in waste water treatment because they have been proven to be effective in eliminating aqueous organic contaminants. The pharmaceuticals carbamazepine, ciprofloxacin, diclofenac, metoprolol and sulfamethoxazole as well as the personal care products galaxolide and tonalide were investigated in terms of degradation efficiency and by-product formation in consideration of toxic effects. The substances were largely removed from treatment plant effluent by ozonation, UV- and UV/H(2)O(2)-treatment. Transformation products were detected in all tested treatment processes. Accompanying analysis showed no genotoxic, cytotoxic or estrogenic potential for the investigated compounds after oxidative treatment of real waste waters. The results indicate that by-product formation from ozonation and advanced oxidation processes does not have any negative environmental impact.</description><subject>Animals</subject><subject>Applied sciences</subject><subject>Biodegradation</subject><subject>Biological and medical sciences</subject><subject>Byproducts</subject><subject>Carbamazepine</subject><subject>Chemical wastewater</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Ciprofloxacin</subject><subject>Consumer products</subject><subject>Contaminants</subject><subject>Cytotoxicity</subject><subject>Diclofenac</subject><subject>Drugs</subject><subject>Environmental effects</subject><subject>Environmental impact</subject><subject>Environmental Monitoring</subject><subject>Environmental pollutants toxicology</subject><subject>Evaluation</subject><subject>Exact sciences and technology</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>General purification processes</subject><subject>Genotoxicity</subject><subject>Hydrogen peroxide</subject><subject>Hydrogen Peroxide - chemistry</subject><subject>Hydrologic cycle</subject><subject>Hydrological cycle</subject><subject>Medical sciences</subject><subject>Metoprolol</subject><subject>Organic contaminants</subject><subject>Oxidation</subject><subject>Oxidation-Reduction</subject><subject>Ozonation</subject><subject>Ozone - chemistry</subject><subject>Ozonization</subject><subject>Pharmaceutical Preparations - analysis</subject><subject>Pharmaceutical Preparations - metabolism</subject><subject>Pharmaceuticals</subject><subject>Pollution</subject><subject>Products</subject><subject>Sewage</subject><subject>Sewage treatment</subject><subject>Sewage treatment plants</subject><subject>Sulfamethoxazole</subject><subject>Tonalide</subject><subject>Toxicity Tests</subject><subject>Toxicology</subject><subject>Trace levels</subject><subject>Ultraviolet radiation</subject><subject>Waste Disposal, Fluid - methods</subject><subject>Waste Water - analysis</subject><subject>Waste Water - chemistry</subject><subject>Wastewater</subject><subject>Wastewater treatment</subject><subject>Wastewater treatment plants</subject><subject>Wastewaters</subject><subject>Water</subject><subject>Water Pollutants, Chemical - 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chemistry</topic><topic>Hydrologic cycle</topic><topic>Hydrological cycle</topic><topic>Medical sciences</topic><topic>Metoprolol</topic><topic>Organic contaminants</topic><topic>Oxidation</topic><topic>Oxidation-Reduction</topic><topic>Ozonation</topic><topic>Ozone - chemistry</topic><topic>Ozonization</topic><topic>Pharmaceutical Preparations - analysis</topic><topic>Pharmaceutical Preparations - metabolism</topic><topic>Pharmaceuticals</topic><topic>Pollution</topic><topic>Products</topic><topic>Sewage</topic><topic>Sewage treatment</topic><topic>Sewage treatment plants</topic><topic>Sulfamethoxazole</topic><topic>Tonalide</topic><topic>Toxicity Tests</topic><topic>Toxicology</topic><topic>Trace levels</topic><topic>Ultraviolet radiation</topic><topic>Waste Disposal, Fluid - methods</topic><topic>Waste Water - analysis</topic><topic>Waste Water - chemistry</topic><topic>Wastewater</topic><topic>Wastewater treatment</topic><topic>Wastewater treatment plants</topic><topic>Wastewaters</topic><topic>Water</topic><topic>Water Pollutants, Chemical - 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Academic</collection><jtitle>Water science and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VOM EYSER, C</au><au>BÖRGERS, A</au><au>RICHARD, J</au><au>DOPP, E</au><au>JANZEN, N</au><au>BESTER, K</au><au>TUERK, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical and toxicological evaluation of transformation products during advanced oxidation processes</atitle><jtitle>Water science and technology</jtitle><addtitle>Water Sci Technol</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>68</volume><issue>9</issue><spage>1976</spage><epage>1983</epage><pages>1976-1983</pages><issn>0273-1223</issn><eissn>1996-9732</eissn><coden>WSTED4</coden><abstract>The entry of pharmaceuticals into the water cycle from sewage treatment plants is of growing concern because environmental effects are evident at trace levels. Ozonation, UV- and UV/H(2)O(2)-treatment were tested as an additional step in waste water treatment because they have been proven to be effective in eliminating aqueous organic contaminants. The pharmaceuticals carbamazepine, ciprofloxacin, diclofenac, metoprolol and sulfamethoxazole as well as the personal care products galaxolide and tonalide were investigated in terms of degradation efficiency and by-product formation in consideration of toxic effects. The substances were largely removed from treatment plant effluent by ozonation, UV- and UV/H(2)O(2)-treatment. Transformation products were detected in all tested treatment processes. Accompanying analysis showed no genotoxic, cytotoxic or estrogenic potential for the investigated compounds after oxidative treatment of real waste waters. The results indicate that by-product formation from ozonation and advanced oxidation processes does not have any negative environmental impact.</abstract><cop>London</cop><pub>International Water Association</pub><pmid>24225097</pmid><doi>10.2166/wst.2013.452</doi><tpages>8</tpages></addata></record> |
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subjects | Animals Applied sciences Biodegradation Biological and medical sciences Byproducts Carbamazepine Chemical wastewater Chromatography, High Pressure Liquid Ciprofloxacin Consumer products Contaminants Cytotoxicity Diclofenac Drugs Environmental effects Environmental impact Environmental Monitoring Environmental pollutants toxicology Evaluation Exact sciences and technology Gas Chromatography-Mass Spectrometry General purification processes Genotoxicity Hydrogen peroxide Hydrogen Peroxide - chemistry Hydrologic cycle Hydrological cycle Medical sciences Metoprolol Organic contaminants Oxidation Oxidation-Reduction Ozonation Ozone - chemistry Ozonization Pharmaceutical Preparations - analysis Pharmaceutical Preparations - metabolism Pharmaceuticals Pollution Products Sewage Sewage treatment Sewage treatment plants Sulfamethoxazole Tonalide Toxicity Tests Toxicology Trace levels Ultraviolet radiation Waste Disposal, Fluid - methods Waste Water - analysis Waste Water - chemistry Wastewater Wastewater treatment Wastewater treatment plants Wastewaters Water Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity Water treatment Water treatment and pollution Xenoestrogens |
title | Chemical and toxicological evaluation of transformation products during advanced oxidation processes |
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