Interleukin 6 Stimulates Endothelial Binding and Transport of High-Density Lipoprotein Through Induction of Endothelial Lipase

OBJECTIVE—In the reverse cholesterol transport pathway, high-density lipoprotein (HDL) passes the endothelial cell barrier by mechanisms involving the scavenger receptor class B type I and the ATP-binding cassette G1. However, little is known on how inflammation influences this transendothelial tran...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2013-12, Vol.33 (12), p.2699-2706
Hauptverfasser:	Robert, Jérôme, Lehner, Marc, Frank, Saša, Perisa, Damir, von Eckardstein, Arnold, Rohrer, Lucia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Animals ATP Binding Cassette Transporter, Sub-Family G, Member 1 ATP-Binding Cassette Transporters - metabolism Biological Transport Cattle Cells, Cultured Endothelial Cells - drug effects Endothelial Cells - enzymology Endothelial Cells - immunology Enzyme Induction Enzyme Inhibitors - pharmacology Genetic Vectors Humans Inflammation Mediators - metabolism Interleukin-6 - metabolism Lipase - antagonists & inhibitors Lipase - biosynthesis Lipase - genetics Lipoproteins, HDL - metabolism Particle Size RNA Interference Scavenger Receptors, Class B - metabolism Transfection
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