Polymorphisms in the IRF-4 gene, asthma and recurrent bronchitis in children

Summary Background Interferon‐regulatory factors (IRFs) play a crucial role in immunity, not only influencing interferon expression but also T cell differentiation. IRF‐4 was only recently recognized as a further major player in T cell differentiation. Objective As IRF‐1 polymorphisms were shown to...

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Veröffentlicht in:	Clinical and experimental allergy 2013-10, Vol.43 (10), p.1152-1159
Hauptverfasser:	Pinto, L. A., Michel, S., Klopp, N., Vogelberg, C., von Berg, A., Bufe, A., Heinzmann, A., Laub, O., Simma, B., Frischer, T., Genuneit, J., Gorski, M., Illig, T., Kabesch, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Alleles asthma Asthma - genetics bronchitis Bronchitis - genetics Child children Cross-Sectional Studies Exons Gene Frequency Genetic Predisposition to Disease Genotype Humans Interferon Regulatory Factors - genetics Odds Ratio Polymorphism, Genetic Polymorphism, Single Nucleotide polymorphisms Recurrence wheezing
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