Fish Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients
Previous studies have shown that n-3 polyunsaturated fatty acids n-3 (n-3 PUFA) have several anticancer effects, especially attributed to their ability to modulate a variety of genomic and immune responses. In this context, this randomized, prospective, controlled clinical trial was conducted in ord...
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| Veröffentlicht in: | Lipids 2013-09, Vol.48 (9), p.879-888 |
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| creator | Mocellin, Michel Carlos Pastore e Silva, Juliana de Aguiar Camargo, Carolina de Quadros Fabre, Maria Emília de Souza Gevaerd, Scheila Naliwaiko, Katya Moreno, Yara Maria Franco Nunes, Everson Araújo Trindade, Erasmo Benicio Santos de Moraes |
| description | Previous studies have shown that n-3 polyunsaturated fatty acids n-3 (n-3 PUFA) have several anticancer effects, especially attributed to their ability to modulate a variety of genomic and immune responses. In this context, this randomized, prospective, controlled clinical trial was conducted in order to check whether supplementation of 2 g/day of fish oil for 9 weeks alters the production of inflammatory markers, the plasma fatty acid profile and the nutritional status in patients with colorectal cancer (CRC). Eleven adults with CRC in chemotherapy were randomized into two groups: (a) supplemented (SG) daily with 2 g/day of encapsulated fish oil [providing 600 mg/day of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA)] for 9 weeks (
n
= 6), and (b) control (CG) (
n
= 5). All outcomes were evaluated on the day before the first chemotherapy session and 9 weeks later. Plasma TNF-α, IL-1β, IL-10 and IL-17A, the pro/anti-inflammatory balance (ratio TNF-α/IL-10 and IL-1β/IL10) and serum albumin, showed no significant changes between times and study groups (
p
> 0.05). C-reactive protein (CRP) and the CRP/albumin ratio showed opposite behavior in groups, significantly reducing their values in SG (
p
|
| doi_str_mv | 10.1007/s11745-013-3816-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1458537570</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3050043621</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4539-c4289f256914271319de1aa43a1a1dd8f68ff6308ff3bf089c7be927201043963</originalsourceid><addsrcrecordid>eNqFkcFu1DAQhi0EokvhAbggS1y4hHpiJ7aPq5SFlVZ0VcHZ8iaTxVXiFDtptU_RV66jFISQEJexbH__r5n5CXkL7CMwJi8igBRFxoBnXEGZsWdkBUWhMs2ZfE5WjOUiEzmDM_Iqxpt0BaGLl-Qs50opDnJFHjYu_qBXrqOXWAe0ESOtsmu09ejukO7DMKLzF-vuMPXO02s7uoFu-9sw3Dl_pF-nMbj05G03s0c_RBep9Q3ddzb2lm7sOJ7ounbN_N-6DmmyqYZuCFiPSVVZX2Og-2SMfoyvyYvWdhHfPJ3n5Pvm07fqS7a7-ryt1rusFgXXqeZKt3lRahC5BA66QbBWcAsWmka1pWrbkrNU-aFlStfygDqXaRdMcF3yc_Jh8U2T_JwwjqZ3scausx6HKRoQhSq4LCRL6Pu_0JthCmnimcpLobniPFGwUHUYYgzYmtvgehtOBpiZ0zJLWialZea0zOz87sl5OvTY_Fb8iicBcgHu0-JO_3c0u-3-kimpkzJflDGJ_BHDH03_s59HOV-vhA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1426493833</pqid></control><display><type>article</type><title>Fish Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>SpringerLink Journals - AutoHoldings</source><creator>Mocellin, Michel Carlos ; Pastore e Silva, Juliana de Aguiar ; Camargo, Carolina de Quadros ; Fabre, Maria Emília de Souza ; Gevaerd, Scheila ; Naliwaiko, Katya ; Moreno, Yara Maria Franco ; Nunes, Everson Araújo ; Trindade, Erasmo Benicio Santos de Moraes</creator><creatorcontrib>Mocellin, Michel Carlos ; Pastore e Silva, Juliana de Aguiar ; Camargo, Carolina de Quadros ; Fabre, Maria Emília de Souza ; Gevaerd, Scheila ; Naliwaiko, Katya ; Moreno, Yara Maria Franco ; Nunes, Everson Araújo ; Trindade, Erasmo Benicio Santos de Moraes</creatorcontrib><description>Previous studies have shown that n-3 polyunsaturated fatty acids n-3 (n-3 PUFA) have several anticancer effects, especially attributed to their ability to modulate a variety of genomic and immune responses. In this context, this randomized, prospective, controlled clinical trial was conducted in order to check whether supplementation of 2 g/day of fish oil for 9 weeks alters the production of inflammatory markers, the plasma fatty acid profile and the nutritional status in patients with colorectal cancer (CRC). Eleven adults with CRC in chemotherapy were randomized into two groups: (a) supplemented (SG) daily with 2 g/day of encapsulated fish oil [providing 600 mg/day of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA)] for 9 weeks (
n
= 6), and (b) control (CG) (
n
= 5). All outcomes were evaluated on the day before the first chemotherapy session and 9 weeks later. Plasma TNF-α, IL-1β, IL-10 and IL-17A, the pro/anti-inflammatory balance (ratio TNF-α/IL-10 and IL-1β/IL10) and serum albumin, showed no significant changes between times and study groups (
p
> 0.05). C-reactive protein (CRP) and the CRP/albumin ratio showed opposite behavior in groups, significantly reducing their values in SG (
p
< 0.05). Plasma proportions of EPA and DHA increased 1.8 and 1.4 times, respectively, while the ARA reduced approximately 0.6 times with the supplementation (9 weeks vs baseline,
p
< 0.05). Patients from SG gained 1.2 kg (median) while the CG lost −0.5 kg (median) during the 9 weeks of chemotherapy (
p
= 0.72). These results demonstrate that 2 g/day of fish oil for 9 weeks of chemotherapy improves CRP values, CRP/albumin status, plasma fatty acid profile and potentially prevents weight loss during treatment.</description><identifier>ISSN: 0024-4201</identifier><identifier>EISSN: 1558-9307</identifier><identifier>DOI: 10.1007/s11745-013-3816-0</identifier><identifier>PMID: 23888317</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Animals ; Biomedical and Life Sciences ; Body Mass Index ; C-Reactive Protein - metabolism ; Chemotherapy ; Colorectal cancer ; Colorectal carcinoma ; Colorectal Neoplasms - blood ; Colorectal Neoplasms - drug therapy ; Cytokines ; Dietary Supplements ; Docosahexaenoic Acids - administration & dosage ; Docosahexaenoic Acids - blood ; Docosahexaenoic Acids - therapeutic use ; Drug Administration Schedule ; Eicosapentaenoic Acid - administration & dosage ; Eicosapentaenoic Acid - blood ; Eicosapentaenoic Acid - therapeutic use ; Fatty acid profile ; Fatty Acids - blood ; Female ; Fish oil ; Fish oils ; Fish Oils - administration & dosage ; Fish Oils - blood ; Fish Oils - therapeutic use ; Humans ; Interleukin-10 - blood ; Interleukin-17 - blood ; Interleukin-1beta - blood ; Life Sciences ; Lipidology ; Male ; Medical Biochemistry ; Medicinal Chemistry ; Microbial Genetics and Genomics ; Middle Aged ; Neurochemistry ; Nutrition ; Nutritional Status ; n‐3 Polyunsaturated fatty acids ; Original Article ; Polyunsaturated fatty acids ; Prognosis ; Prospective Studies ; Serum Albumin - metabolism ; Treatment Outcome ; Tumor Necrosis Factor-alpha - blood</subject><ispartof>Lipids, 2013-09, Vol.48 (9), p.879-888</ispartof><rights>AOCS 2013</rights><rights>2013 American Oil Chemists' Society (AOCS)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4539-c4289f256914271319de1aa43a1a1dd8f68ff6308ff3bf089c7be927201043963</citedby><cites>FETCH-LOGICAL-c4539-c4289f256914271319de1aa43a1a1dd8f68ff6308ff3bf089c7be927201043963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11745-013-3816-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11745-013-3816-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,41464,42533,45550,45551,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23888317$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mocellin, Michel Carlos</creatorcontrib><creatorcontrib>Pastore e Silva, Juliana de Aguiar</creatorcontrib><creatorcontrib>Camargo, Carolina de Quadros</creatorcontrib><creatorcontrib>Fabre, Maria Emília de Souza</creatorcontrib><creatorcontrib>Gevaerd, Scheila</creatorcontrib><creatorcontrib>Naliwaiko, Katya</creatorcontrib><creatorcontrib>Moreno, Yara Maria Franco</creatorcontrib><creatorcontrib>Nunes, Everson Araújo</creatorcontrib><creatorcontrib>Trindade, Erasmo Benicio Santos de Moraes</creatorcontrib><title>Fish Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients</title><title>Lipids</title><addtitle>Lipids</addtitle><addtitle>Lipids</addtitle><description>Previous studies have shown that n-3 polyunsaturated fatty acids n-3 (n-3 PUFA) have several anticancer effects, especially attributed to their ability to modulate a variety of genomic and immune responses. In this context, this randomized, prospective, controlled clinical trial was conducted in order to check whether supplementation of 2 g/day of fish oil for 9 weeks alters the production of inflammatory markers, the plasma fatty acid profile and the nutritional status in patients with colorectal cancer (CRC). Eleven adults with CRC in chemotherapy were randomized into two groups: (a) supplemented (SG) daily with 2 g/day of encapsulated fish oil [providing 600 mg/day of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA)] for 9 weeks (
n
= 6), and (b) control (CG) (
n
= 5). All outcomes were evaluated on the day before the first chemotherapy session and 9 weeks later. Plasma TNF-α, IL-1β, IL-10 and IL-17A, the pro/anti-inflammatory balance (ratio TNF-α/IL-10 and IL-1β/IL10) and serum albumin, showed no significant changes between times and study groups (
p
> 0.05). C-reactive protein (CRP) and the CRP/albumin ratio showed opposite behavior in groups, significantly reducing their values in SG (
p
< 0.05). Plasma proportions of EPA and DHA increased 1.8 and 1.4 times, respectively, while the ARA reduced approximately 0.6 times with the supplementation (9 weeks vs baseline,
p
< 0.05). Patients from SG gained 1.2 kg (median) while the CG lost −0.5 kg (median) during the 9 weeks of chemotherapy (
p
= 0.72). These results demonstrate that 2 g/day of fish oil for 9 weeks of chemotherapy improves CRP values, CRP/albumin status, plasma fatty acid profile and potentially prevents weight loss during treatment.</description><subject>Adult</subject><subject>Aged</subject><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Body Mass Index</subject><subject>C-Reactive Protein - metabolism</subject><subject>Chemotherapy</subject><subject>Colorectal cancer</subject><subject>Colorectal carcinoma</subject><subject>Colorectal Neoplasms - blood</subject><subject>Colorectal Neoplasms - drug therapy</subject><subject>Cytokines</subject><subject>Dietary Supplements</subject><subject>Docosahexaenoic Acids - administration & dosage</subject><subject>Docosahexaenoic Acids - blood</subject><subject>Docosahexaenoic Acids - therapeutic use</subject><subject>Drug Administration Schedule</subject><subject>Eicosapentaenoic Acid - administration & dosage</subject><subject>Eicosapentaenoic Acid - blood</subject><subject>Eicosapentaenoic Acid - therapeutic use</subject><subject>Fatty acid profile</subject><subject>Fatty Acids - blood</subject><subject>Female</subject><subject>Fish oil</subject><subject>Fish oils</subject><subject>Fish Oils - administration & dosage</subject><subject>Fish Oils - blood</subject><subject>Fish Oils - therapeutic use</subject><subject>Humans</subject><subject>Interleukin-10 - blood</subject><subject>Interleukin-17 - blood</subject><subject>Interleukin-1beta - blood</subject><subject>Life Sciences</subject><subject>Lipidology</subject><subject>Male</subject><subject>Medical Biochemistry</subject><subject>Medicinal Chemistry</subject><subject>Microbial Genetics and Genomics</subject><subject>Middle Aged</subject><subject>Neurochemistry</subject><subject>Nutrition</subject><subject>Nutritional Status</subject><subject>n‐3 Polyunsaturated fatty acids</subject><subject>Original Article</subject><subject>Polyunsaturated fatty acids</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Serum Albumin - metabolism</subject><subject>Treatment Outcome</subject><subject>Tumor Necrosis Factor-alpha - blood</subject><issn>0024-4201</issn><issn>1558-9307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkcFu1DAQhi0EokvhAbggS1y4hHpiJ7aPq5SFlVZ0VcHZ8iaTxVXiFDtptU_RV66jFISQEJexbH__r5n5CXkL7CMwJi8igBRFxoBnXEGZsWdkBUWhMs2ZfE5WjOUiEzmDM_Iqxpt0BaGLl-Qs50opDnJFHjYu_qBXrqOXWAe0ESOtsmu09ejukO7DMKLzF-vuMPXO02s7uoFu-9sw3Dl_pF-nMbj05G03s0c_RBep9Q3ddzb2lm7sOJ7ounbN_N-6DmmyqYZuCFiPSVVZX2Og-2SMfoyvyYvWdhHfPJ3n5Pvm07fqS7a7-ryt1rusFgXXqeZKt3lRahC5BA66QbBWcAsWmka1pWrbkrNU-aFlStfygDqXaRdMcF3yc_Jh8U2T_JwwjqZ3scausx6HKRoQhSq4LCRL6Pu_0JthCmnimcpLobniPFGwUHUYYgzYmtvgehtOBpiZ0zJLWialZea0zOz87sl5OvTY_Fb8iicBcgHu0-JO_3c0u-3-kimpkzJflDGJ_BHDH03_s59HOV-vhA</recordid><startdate>201309</startdate><enddate>201309</enddate><creator>Mocellin, Michel Carlos</creator><creator>Pastore e Silva, Juliana de Aguiar</creator><creator>Camargo, Carolina de Quadros</creator><creator>Fabre, 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Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients</title><author>Mocellin, Michel Carlos ; Pastore e Silva, Juliana de Aguiar ; Camargo, Carolina de Quadros ; Fabre, Maria Emília de Souza ; Gevaerd, Scheila ; Naliwaiko, Katya ; Moreno, Yara Maria Franco ; Nunes, Everson Araújo ; Trindade, Erasmo Benicio Santos de Moraes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4539-c4289f256914271319de1aa43a1a1dd8f68ff6308ff3bf089c7be927201043963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Body Mass Index</topic><topic>C-Reactive Protein - metabolism</topic><topic>Chemotherapy</topic><topic>Colorectal cancer</topic><topic>Colorectal carcinoma</topic><topic>Colorectal Neoplasms - blood</topic><topic>Colorectal Neoplasms - drug therapy</topic><topic>Cytokines</topic><topic>Dietary Supplements</topic><topic>Docosahexaenoic Acids - administration & dosage</topic><topic>Docosahexaenoic Acids - blood</topic><topic>Docosahexaenoic Acids - therapeutic use</topic><topic>Drug Administration Schedule</topic><topic>Eicosapentaenoic Acid - administration & dosage</topic><topic>Eicosapentaenoic Acid - blood</topic><topic>Eicosapentaenoic Acid - therapeutic use</topic><topic>Fatty acid profile</topic><topic>Fatty Acids - blood</topic><topic>Female</topic><topic>Fish oil</topic><topic>Fish oils</topic><topic>Fish Oils - administration & dosage</topic><topic>Fish Oils - blood</topic><topic>Fish Oils - therapeutic use</topic><topic>Humans</topic><topic>Interleukin-10 - blood</topic><topic>Interleukin-17 - blood</topic><topic>Interleukin-1beta - blood</topic><topic>Life Sciences</topic><topic>Lipidology</topic><topic>Male</topic><topic>Medical Biochemistry</topic><topic>Medicinal Chemistry</topic><topic>Microbial Genetics and Genomics</topic><topic>Middle Aged</topic><topic>Neurochemistry</topic><topic>Nutrition</topic><topic>Nutritional Status</topic><topic>n‐3 Polyunsaturated fatty acids</topic><topic>Original Article</topic><topic>Polyunsaturated fatty acids</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Serum Albumin - metabolism</topic><topic>Treatment Outcome</topic><topic>Tumor Necrosis Factor-alpha - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mocellin, Michel Carlos</creatorcontrib><creatorcontrib>Pastore e Silva, Juliana de Aguiar</creatorcontrib><creatorcontrib>Camargo, Carolina de Quadros</creatorcontrib><creatorcontrib>Fabre, Maria Emília de Souza</creatorcontrib><creatorcontrib>Gevaerd, Scheila</creatorcontrib><creatorcontrib>Naliwaiko, Katya</creatorcontrib><creatorcontrib>Moreno, Yara Maria 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Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mocellin, Michel Carlos</au><au>Pastore e Silva, Juliana de Aguiar</au><au>Camargo, Carolina de Quadros</au><au>Fabre, Maria Emília de Souza</au><au>Gevaerd, Scheila</au><au>Naliwaiko, Katya</au><au>Moreno, Yara Maria Franco</au><au>Nunes, Everson Araújo</au><au>Trindade, Erasmo Benicio Santos de Moraes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fish Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients</atitle><jtitle>Lipids</jtitle><stitle>Lipids</stitle><addtitle>Lipids</addtitle><date>2013-09</date><risdate>2013</risdate><volume>48</volume><issue>9</issue><spage>879</spage><epage>888</epage><pages>879-888</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>Previous studies have shown that n-3 polyunsaturated fatty acids n-3 (n-3 PUFA) have several anticancer effects, especially attributed to their ability to modulate a variety of genomic and immune responses. In this context, this randomized, prospective, controlled clinical trial was conducted in order to check whether supplementation of 2 g/day of fish oil for 9 weeks alters the production of inflammatory markers, the plasma fatty acid profile and the nutritional status in patients with colorectal cancer (CRC). Eleven adults with CRC in chemotherapy were randomized into two groups: (a) supplemented (SG) daily with 2 g/day of encapsulated fish oil [providing 600 mg/day of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA)] for 9 weeks (
n
= 6), and (b) control (CG) (
n
= 5). All outcomes were evaluated on the day before the first chemotherapy session and 9 weeks later. Plasma TNF-α, IL-1β, IL-10 and IL-17A, the pro/anti-inflammatory balance (ratio TNF-α/IL-10 and IL-1β/IL10) and serum albumin, showed no significant changes between times and study groups (
p
> 0.05). C-reactive protein (CRP) and the CRP/albumin ratio showed opposite behavior in groups, significantly reducing their values in SG (
p
< 0.05). Plasma proportions of EPA and DHA increased 1.8 and 1.4 times, respectively, while the ARA reduced approximately 0.6 times with the supplementation (9 weeks vs baseline,
p
< 0.05). Patients from SG gained 1.2 kg (median) while the CG lost −0.5 kg (median) during the 9 weeks of chemotherapy (
p
= 0.72). These results demonstrate that 2 g/day of fish oil for 9 weeks of chemotherapy improves CRP values, CRP/albumin status, plasma fatty acid profile and potentially prevents weight loss during treatment.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23888317</pmid><doi>10.1007/s11745-013-3816-0</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0024-4201 |
| ispartof | Lipids, 2013-09, Vol.48 (9), p.879-888 |
| issn | 0024-4201 1558-9307 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1458537570 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Animals Biomedical and Life Sciences Body Mass Index C-Reactive Protein - metabolism Chemotherapy Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - blood Colorectal Neoplasms - drug therapy Cytokines Dietary Supplements Docosahexaenoic Acids - administration & dosage Docosahexaenoic Acids - blood Docosahexaenoic Acids - therapeutic use Drug Administration Schedule Eicosapentaenoic Acid - administration & dosage Eicosapentaenoic Acid - blood Eicosapentaenoic Acid - therapeutic use Fatty acid profile Fatty Acids - blood Female Fish oil Fish oils Fish Oils - administration & dosage Fish Oils - blood Fish Oils - therapeutic use Humans Interleukin-10 - blood Interleukin-17 - blood Interleukin-1beta - blood Life Sciences Lipidology Male Medical Biochemistry Medicinal Chemistry Microbial Genetics and Genomics Middle Aged Neurochemistry Nutrition Nutritional Status n‐3 Polyunsaturated fatty acids Original Article Polyunsaturated fatty acids Prognosis Prospective Studies Serum Albumin - metabolism Treatment Outcome Tumor Necrosis Factor-alpha - blood |
| title | Fish Oil Decreases C-Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T22%3A22%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fish%20Oil%20Decreases%20C-Reactive%20Protein/Albumin%20Ratio%20Improving%20Nutritional%20Prognosis%20and%20Plasma%20Fatty%20Acid%20Profile%20in%20Colorectal%20Cancer%20Patients&rft.jtitle=Lipids&rft.au=Mocellin,%20Michel%20Carlos&rft.date=2013-09&rft.volume=48&rft.issue=9&rft.spage=879&rft.epage=888&rft.pages=879-888&rft.issn=0024-4201&rft.eissn=1558-9307&rft_id=info:doi/10.1007/s11745-013-3816-0&rft_dat=%3Cproquest_cross%3E3050043621%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1426493833&rft_id=info:pmid/23888317&rfr_iscdi=true |